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PRAS40 regulates mTORC1 kinase activity by functioning as a direct inhibitor of substrate binding.

Wang L, Harris TE, Roth RA, Lawrence JC
J Biol Chem. 2007 Jul 6. 282(27):20036-44. (Link opens in a new window) PubMed (Link opens in a new window) Article

Plasmids from Article

ID Plasmid Purpose
15672PRAS40 (mouse) shRNA
15673HA PRAS40 F129A
15674HA PRAS40 S183A
15675HA PRAS40 P185A

Antibodies from Article