STAT3-driven transcription depends upon the dimethylation of K49 by EZH2.

Dasgupta M, Dermawan JK, Willard B, Stark GR
Proc Natl Acad Sci U S A. 2015 Mar 31;112(13):3985-90. doi: 10.1073/pnas.1503152112. Epub 2015 Mar 12. (Link opens in a new window) PubMed (Link opens in a new window) Article

Plasmids from Article

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ID	Plasmid	Purpose
71449	pLEGFP-K685R-STAT3	Retroviral expression of K685R-STAT3. Please note that this plasmid contains K685R-STAT3 tagged with FLAG, not GFP.
71448	pLEGFP-K140R-STAT3	Retroviral expression of K140R-STAT3. Please note that this plasmid contains K140R-STAT3 tagged with FLAG, not GFP.
71447	pLEGFP-K49R-STAT3	Retroviral expression of K49R-STAT3. Please note that this plasmid contains K49R-STAT3 tagged with FLAG, not GFP.
71446	pLEGFP-S727A-STAT3	Retroviral expression of S727A-STAT3. Please note that this plasmid contains S727A-STAT3 tagged with FLAG, not GFP.