Mediator kinase inhibition further activates super-enhancer-associated genes in AML.
Pelish HE, Liau BB, Nitulescu II, Tangpeerachaikul A, Poss ZC, Da Silva DH, Caruso BT, Arefolov A, Fadeyi O, Christie AL, Du K, Banka D, Schneider EV, Jestel A, Zou G, Si C, Ebmeier CC, Bronson RT, Krivtsov AV, Myers AG, Kohl NE, Kung AL, Armstrong SA, Lemieux ME, Taatjes DJ, Shair MD
Nature. 2015 Sep 28. doi: 10.1038/nature14904.
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Plasmids from Article
| ID | Plasmid | Purpose |
|---|---|---|
| 68856 | pLVX-Flag-CDK8-WT-IRES-mCherry | Expresses Human CDK8 Wild-Type |
| 68857 | pLVX-Flag-CDK8-W105M-IRES-mCherry | Expresses Human CDK8 W105M Mutant |
| 68858 | pLVX-Flag-CDK19-WT-IRES-ZsGreen | Expresses Human CDK19 Wild-Type |
| 68859 | pLVX-Flag-CDK19-W105M-IRES-ZsGreen | Expresses Human CDK19 W105M Mutant |