Tet proteins can convert 5-methylcytosine to 5-formylcytosine and 5-carboxylcytosine.
Ito S, Shen L, Dai Q, Wu SC, Collins LB, Swenberg JA, He C, Zhang Y
Science. 2011 Sep 2;333(6047):1300-3. doi: 10.1126/science.1210597. Epub 2011 Jul 21.
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Plasmids from Article
| ID | Plasmid | Purpose |
|---|---|---|
| 70129 | pcDNA3-Flag-Tet1 CD | Express flag-tagged mouse Tet1 catalytic domain. |
| 72218 | pcDNA3-Flag-Tet1 CD Mut | Express flag-tagged mouse Tet1 catalytic domain - catalytic dead mutant. |
| 72219 | pcDNA3-Flag-Tet2 CD | Express flag-tagged mouse Tet2 catalytic domain. |
| 72220 | pcDNA3-Flag-Tet2 CD Mut | Express flag-tagged mouse Tet2 catalytic domain - catalytic dead mutant. |
| 72222 | pcDNA3-Flag-Tet3 CD Mut | Express flag-tagged mouse Tet3 catalytic domain - catalytic dead mutant. |