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Cardiac-specific YAP activation improves cardiac function and survival in an experimental murine MI model.

Lin Z, von Gise A, Zhou P, Gu F, Ma Q, Jiang J, Yau AL, Buck JN, Gouin KA, van Gorp PR, Zhou B, Chen J, Seidman JG, Wang DZ, Pu WT
Circ Res. 2014 Jul 18;115(3):354-63. doi: 10.1161/CIRCRESAHA.115.303632. Epub 2014 May 15. (Link opens in a new window) PubMed (Link opens in a new window) Article

Plasmids from Article

ID Plasmid Purpose
69915pAAV:cTNT::LuciferaseUsed to package AAV9:cTNT::luciferase. Specifically transduce cardiomyocytes.
86558AAV9:cTNT::3Flag-hYAP S127ATo produce cardiac specific adeno-associated virus expressing activated human YAP.

Antibodies from Article