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Constant rate of p53 tetramerization in response to DNA damage controls the p53 response.

Gaglia G, Lahav G
Mol Syst Biol. 2014 Oct 24;10:753. doi: 10.15252/msb.20145168. (Link opens in a new window) PubMed

Plasmids from Article

ID Plasmid Purpose
69582pRRLNeo-pEF1a-p53ash-mKate2-splitmVenusNExpresses p53 tagged with mKate2 and split N-term mVenus
69583pRRLHygro-pEF1a-p53ash-mKate2-splitmVenusCExpresses p53 tagged with mKate2 and split C-term mVenus
69584pRRLNeo-pEF1a-p53ashL344A-mKate2-splitmVenusNExpresses mutated p53-L344A tagged with mKate2 and split N-term mVenus
69585pRRLHygro-pEF1a-p53ashL344A-mKate2-splitmVenusCExpresses mutated p53-L344A tagged with mKate2 and split C-term mVenus
69586pRRLNeo-pEF1a-p53ashL344P-mKate2-splitmVenusNExpresses mutated p53-L344P tagged with mKate2 and split N-term mVenus
69587pRRLHygro-pEF1a-p53ashL344P-mKate2-splitmVenusCExpresses mutated p53-L344P tagged with mKate2 and split C-term mVenus

Antibodies from Article