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TRIM5 is an innate immune sensor for the retrovirus capsid lattice.

Pertel T, Hausmann S, Morger D, Zuger S, Guerra J, Lascano J, Reinhard C, Santoni FA, Uchil PD, Chatel L, Bisiaux A, Albert ML, Strambio-De-Castillia C, Mothes W, Pizzato M, Grutter MG, Luban J
Nature. 2011 Apr 21;472(7343):361-5. doi: 10.1038/nature09976. (Link opens in a new window) PubMed (Link opens in a new window) Article

Plasmids from Article

ID Plasmid Purpose
74171pAIPLentiviral vector for expression of heterologous genes
90996pALPSLentiviral vector for expression of heterologous genes

Antibodies from Article