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The L-VP35 and L-L interaction domains reside in the amino terminus of the Ebola virus L protein and are potential targets for antivirals.

Trunschke M, Conrad D, Enterlein S, Olejnik J, Brauburger K, Muhlberger E
Virology. 2013 Jul 5;441(2):135-45. doi: 10.1016/j.virol.2013.03.013. Epub 2013 Apr 11. (Link opens in a new window) PubMed (Link opens in a new window) Article

Plasmids from Article

ID Plasmid Purpose
68121pTM1_VP35_ZEBOVEncodes for Ebola Virus Zaire VP35 under control of a T7 RNA polymerase promoter.
69119pTM1_VP30_ZEBOVEncodes for Ebola Virus Zaire VP30 under control of a T7 RNA polymerase promoter
69120pTM1_L_ZEBOVEncodes for Ebola Virus Zaire L under control of a T7 RNA polymerase promoter
69121pTM1_NP_ZEBOVEncodes for Ebola Virus Zaire NP under control of a T7 RNA polymerase promoter
69358p2,0_3E5E_luciferaseEncodes for Ebola Minigenome with luciferase reporter gene under control of a T7 RNA polymerase promoter

Antibodies from Article