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A cell-based assay to screen stimulators of the Hippo pathway reveals the inhibitory effect of dobutamine on the YAP-dependent gene transcription.

Bao Y, Nakagawa K, Yang Z, Ikeda M, Withanage K, Ishigami-Yuasa M, Okuno Y, Hata S, Nishina H, Hata Y
J Biochem. 2011 Aug;150(2):199-208. doi: 10.1093/jb/mvr063. Epub 2011 May 17. (Link opens in a new window) PubMed (Link opens in a new window) Article

Plasmids from Article

ID Plasmid Purpose
66850pLL3.7 EGFPC2 TAZExpress GFP-fused TAZ by lentivirus
66851pClneoMyc-LATS1Express Myc-tagged LATS1 in mammalian cells
66852pClneoMyc-LATS2Express Myc-tagged LATS2 in mammalian cells
66853pFLAG-YAP1Express FLAG-tagged YAP1 in mammalian cells

Antibodies from Article