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Tight control of hypoxia-inducible factor-alpha transient dynamics is essential for cell survival in hypoxia.

Bagnall J, Leedale J, Taylor SE, Spiller DG, White MR, Sharkey KJ, Bearon RN, See V
J Biol Chem. 2014 Feb 28;289(9):5549-64. doi: 10.1074/jbc.M113.500405. Epub 2014 Jan 6. (Link opens in a new window) PubMed (Link opens in a new window) Article

Plasmids from Article

ID Plasmid Purpose
87204pg-HIF-1alpha-EGFPC-terminally EGFP-tagged human HIF-1a
87207pg-EGFP-HIF-2alphaN-terminally EGFP-tagged human HIF-2a/EPAS
87210pg-proPHD2-PHD2-EGFPPHD2-EGFP expressed under the control of the PHD2 promoter
87211pg-ODD-EGFPHIF-1a's ODD domain fused to EGFP
87218pHIV-ODD-EGFP-IRES-dTomatolentiviral expression of ODD-EGFP

Antibodies from Article