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GATA3 transcription factor abrogates Smad4 transcription factor-mediated fascin overexpression, invadopodium formation, and breast cancer cell invasion.

Sun J, He H, Pillai S, Xiong Y, Challa S, Xu L, Chellappan S, Yang S
J Biol Chem. 2013 Dec 27;288(52):36971-82. doi: 10.1074/jbc.M113.506535. Epub 2013 Nov 14. (Link opens in a new window) PubMed (Link opens in a new window) Article

Plasmids from Article

ID Plasmid Purpose
89823pGL3-Basic-Fascin-Promoter (-402-0)Promoter luciferase assay
89825pGL3-Basic-Fascin-Promoter 402 mutationFascin promoter for luciferase assay
89826pGL3-Basic-Fascin-Promoter (-210-0)Fascin promoter for luciferase assay
89830pLPCX2-HA-GATA3 N1(1-259)Express GATA3 N1 in mammalian cells
89831pLPCX2-HA-GATA3 N2(1-294)Express GATA3 N2 in mammalian cells
89832pLPCX2-HA-GATA3 C1(259-443)Express GATA3 C1 in mammalian cells
89834pLPCX2-FLAG-Smad4Express Smad4 in mammalian cells
89835pLPCX2-HA-GATA3 FLExpress GATA3 in mammalian cells
90316pLPCX2-HA-GATA3 C1(295-443)Express GATA3 C2 in mammalian cells

Antibodies from Article