Inducible dimerization and inducible cleavage reveal a requirement for both processes in caspase-8 activation.
Oberst A, Pop C, Tremblay AG, Blais V, Denault JB, Salvesen GS, Green DR
J Biol Chem. 2010 May 28;285(22):16632-42. doi: 10.1074/jbc.M109.095083. Epub 2010 Mar 22.
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Plasmids from Article
| ID | Plasmid | Purpose |
|---|---|---|
| 65800 | pcDNA3.1-V5-hTEV | expresses human codon-optimised TEV protease |
| 82712 | Fv-hCaspase 8-2A-GFP | express human caspase 8 in mammalian cells |
| 82713 | Fv-hCaspase 8 (C/A)-2A-GFP | express human caspase 8 in mammalian cells |