The activity of a human endoplasmic reticulum-associated degradation E3, gp78, requires its Cue domain, RING finger, and an E2-binding site.

Chen B, Mariano J, Tsai YC, Chan AH, Cohen M, Weissman AM
Proc Natl Acad Sci U S A. 2006 Jan 10. 103(2):341-6. (Link opens in a new window) PubMed (Link opens in a new window) Article

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