Tumor suppressor activity of the ERK/MAPK pathway by promoting selective protein degradation.
Deschenes-Simard X, Gaumont-Leclerc MF, Bourdeau V, Lessard F, Moiseeva O, Forest V, Igelmann S, Mallette FA, Saba-El-Leil MK, Meloche S, Saad F, Mes-Masson AM, Ferbeyre G
Genes Dev. 2013 Apr 15;27(8):900-15. doi: 10.1101/gad.203984.112. Epub 2013 Apr 18.
(Link opens in a new window)
PubMed
(Link opens in a new window)
Article
Plasmids from Article
| ID | Plasmid | Purpose |
|---|---|---|
| 65228 | shERK1a-mlpx-puro | encodes a shRNA against ERK1 |
| 65229 | shERK2a-mlpx-puro | encodes a shRNA against ERK2 |
| 65230 | shERK2b-mlpx-puro | encodes a shRNA against ERK2 |
| 65231 | shERK2b-mlpx-neo | encodes a shRNA against ERK2 |
| 65232 | shCTL-mlpx-puro | encodes a non-targeting control shRNA |
| 65233 | shCTL-mlpx-neo | encodes a non-targeting control shRNA |