Constitutively active AKT depletes hematopoietic stem cells and induces leukemia in mice.
Kharas MG, Okabe R, Ganis JJ, Gozo M, Khandan T, Paktinat M, Gilliland DG, Gritsman K
Blood. 2010 Feb 18;115(7):1406-15. doi: 10.1182/blood-2009-06-229443. Epub 2009 Dec 14.
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Plasmids from Article
| ID | Plasmid | Purpose |
|---|---|---|
| 65063 | pMSCV-flag-myr-Akt1-IRES-GFP | mammalian retroviral expression plasmid |