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Lin-28B transactivation is necessary for Myc-mediated let-7 repression and proliferation.

Chang TC, Zeitels LR, Hwang HW, Chivukula RR, Wentzel EA, Dews M, Jung J, Gao P, Dang CV, Beer MA, Thomas-Tikhonenko A, Mendell JT
Proc Natl Acad Sci U S A. 2009 Mar 3;106(9):3384-9. doi: 10.1073/pnas.0808300106. Epub 2009 Feb 11. (Link opens in a new window) PubMed (Link opens in a new window) Article

Plasmids from Article

ID Plasmid Purpose
64794pGL3-IRES-Lin28b-P3Luciferase expression driven by Lin28b promoter P3
64795pMSCV-PIG-Lin28bExpresses human Lin28b in mammalian cells

Antibodies from Article