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Transactivation of miR-34a by p53 broadly influences gene expression and promotes apoptosis.

Chang TC, Wentzel EA, Kent OA, Ramachandran K, Mullendore M, Lee KH, Feldmann G, Yamakuchi M, Ferlito M, Lowenstein CJ, Arking DE, Beer MA, Maitra A, Mendell JT
Mol Cell. 2007 Jun 8;26(5):745-52. Epub 2007 May 31. (Link opens in a new window) PubMed (Link opens in a new window) Article

Plasmids from Article

ID Plasmid Purpose
64784pGL3-Basic-IRESLuciferase reporter vector
64786pGL3-IRES-miR34a-P2Luciferase expression driven by miR-34a promoter P2
64787pGL3-IRES-miR34a-P3Luciferase expression driven by miR-34a promoter P3
64788pGL3-IRES-miR34a-P4Luciferase expression driven by miR-34a promoter P4
64789pGL3-IRES-miR34a-P5Luciferase expression driven by miR-34a promoter P5
64790pGL3-IRES-miR34a-P6Luciferase expression driven by miR-34a promoter P6

Antibodies from Article