Yardena Samuels Lab Materials

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Title	Authors	Publication
Analysis of the disintegrin-metalloproteinases family reveals ADAM29 and ADAM7 are often mutated in melanoma.	Wei X, Moncada-Pazos A, Cal S, Soria-Valles C, Gartner J, Rudloff U, Lin JC, Rosenberg SA, Lopez-Otin C, Samuels Y	Hum Mutat. 2011 Jun;32(6):E2148-75. doi: 10.1002/humu.21477. Epub 2011 Feb 24.
Analysis of the matrix metalloproteinase family reveals that MMP8 is often mutated in melanoma.	Palavalli LH, Prickett TD, Wunderlich JR, Wei X, Burrell AS, Porter-Gill P, Davis S, Wang C, Cronin JC, Agrawal NS, Lin JC, Westbroek W, Hoogstraten-Miller S, Molinolo AA, Fetsch P, Filie AC, O'Connell MP, Banister CE, Howard JD, Buckhaults P, Weeraratna AT, Brody LC, Rosenberg SA, Samuels Y	Nat Genet. 2009 May . 41(5):518-20.
Analysis of the tyrosine kinome in melanoma reveals recurrent mutations in ERBB4.	Prickett TD, Agrawal NS, Wei X, Yates KE, Lin JC, Wunderlich JR, Cronin JC, Cruz P, Rosenberg SA, Samuels Y	Nat Genet. 2009 Oct . 41(10):1127-32.
Exon capture analysis of G protein-coupled receptors identifies activating mutations in GRM3 in melanoma.	Prickett TD, Wei X, Cardenas-Navia I, Teer JK, Lin JC, Walia V, Gartner J, Jiang J, Cherukuri PF, Molinolo A, Davies MA, Gershenwald JE, Stemke-Hale K, Rosenberg SA, Margulies EH, Samuels Y	Nat Genet. 2011 Sep 25;43(11):1119-26. doi: 10.1038/ng.950.
Frequent mutations in the MITF pathway in melanoma.	Cronin JC, Wunderlich J, Loftus SK, Prickett TD, Wei X, Ridd K, Vemula S, Burrell AS, Agrawal NS, Lin JC, Banister CE, Buckhaults P, Rosenberg SA, Bastian BC, Pavan WJ, Samuels Y	Pigment Cell Melanoma Res. 2009 Aug . 22(4):435-44.
MAP3K5 expression plasmids	(unpublished)
Mutational and functional analysis reveals ADAMTS18 metalloproteinase as a novel driver in melanoma.	Wei X, Prickett TD, Viloria CG, Molinolo A, Lin JC, Cardenas-Navia I, Cruz P, Rosenberg SA, Davies MA, Gershenwald JE, Lopez-Otin C, Samuels Y	Mol Cancer Res. 2010 Nov . 8(11):1513-25.
Recurrent inactivating RASA2 mutations in melanoma.	Arafeh R, Qutob N, Emmanuel R, Keren-Paz A, Madore J, Elkahloun A, Wilmott JS, Gartner JJ, Di Pizio A, Winograd-Katz S, Sindiri S, Rotkopf R, Dutton-Regester K, Johansson P, Pritchard AL, Waddell N, Hill VK, Lin JC, Hevroni Y, Rosenberg SA, Khan J, Ben-Dor S, Niv MY, Ulitsky I, Mann GJ, Scolyer RA, Hayward NK, Samuels Y	Nat Genet. 2015 Dec;47(12):1408-10. doi: 10.1038/ng.3427. Epub 2015 Oct 26.
RGS7 is recurrently mutated in melanoma and promotes migration and invasion of human cancer cells.	Qutob N, Masuho I, Alon M, Emmanuel R, Cohen I, Di Pizio A, Madore J, Elkahloun A, Ziv T, Levy R, Gartner JJ, Hill VK, Lin JC, Hevroni Y, Greenberg P, Brodezki A, Rosenberg SA, Kosloff M, Hayward NK, Admon A, Niv MY, Scolyer RA, Martemyanov KA, Samuels Y	Sci Rep. 2018 Jan 12;8(1):653. doi: 10.1038/s41598-017-18851-4.
TRRAP	(unpublished)

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	ID	Plasmid	Gene/Insert	Vector Type	Publication
100.3.726172.32103	32103	CbS-Flag-TRRAP	Transformation/transcription domain-associated protein (TRRAP Human)	Mammalian Expression	TRRAP (unpublished)
100.1.316938.31151	31151	pCMV-Tag4A-MITF-M (wt)	MITF-M (MITF Human)	Mammalian Expression, Bacterial Expression	Frequent mutations in the MITF pathway in melanoma. Pigment Cell Melanoma Res. 2009 Aug . 22(4):435-44.
50.3.897832.47104	47104	pcDNA3.1-MAP3K5 (WT)	MAP3K5 (MAP3K5 Human)	Mammalian Expression	MAP3K5 expression plasmids (unpublished)
50.3.656415.29527	29527	pcDNA3.1-ERBB4	ERBB4 (ERBB4 Human)	Mammalian Expression	Analysis of the tyrosine kinome in melanoma reveals recurrent mutations in ERBB4. Nat Genet. 2009 Oct . 41(10):1127-32.
20.1.028713.31798	31798	pCDF1-GRM3 WT	GRM3 (GRM3 Human)	Mammalian Expression, Lentiviral	Exon capture analysis of G protein-coupled receptors identifies activating mutations in GRM3 in melanoma. Nat Genet. 2011 Sep 25;43(11):1119-26. doi: 10.1038/ng.950.
20.0.841777.29545	29545	pCMV-Tag4A-MMP8 Wt	Metalloproteinase protein 8 (MMP8 Human)	Mammalian Expression, Bacterial Expression	Analysis of the matrix metalloproteinase family reveals that MMP8 is often mutated in melanoma. Nat Genet. 2009 May . 41(5):518-20.
20.0.476722.29536	29536	pCDF1-ERBB4 WT	ERBB4 (ERBB4 Human)	Mammalian Expression, Lentiviral	Analysis of the tyrosine kinome in melanoma reveals recurrent mutations in ERBB4. Nat Genet. 2009 Oct . 41(10):1127-32.
20.0.196650.29533	29533	pcDNA3.1-ERBB4 (kinase dead)	ERBB4 (ERBB4 Human)	Mammalian Expression	Analysis of the tyrosine kinome in melanoma reveals recurrent mutations in ERBB4. Nat Genet. 2009 Oct . 41(10):1127-32.
	29528	pcDNA3.1-ERBB4 (E317K)	ERBB4 (ERBB4 Human)	Mammalian Expression	Analysis of the tyrosine kinome in melanoma reveals recurrent mutations in ERBB4. Nat Genet. 2009 Oct . 41(10):1127-32.
	29529	pcDNA3.1-ERBB4 (E452K)	ERBB4 (ERBB4 Human)	Mammalian Expression	Analysis of the tyrosine kinome in melanoma reveals recurrent mutations in ERBB4. Nat Genet. 2009 Oct . 41(10):1127-32.