Veerle Baekelandt Lab Materials

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Title	Authors	Publication
ATP13A2 deficiency disrupts lysosomal polyamine export.	van Veen S, Martin S, Van den Haute C, Benoy V, Lyons J, Vanhoutte R, Kahler JP, Decuypere JP, Gelders G, Lambie E, Zielich J, Swinnen JV, Annaert W, Agostinis P, Ghesquiere B, Verhelst S, Baekelandt V, Eggermont J, Vangheluwe P	Nature. 2020 Feb;578(7795):419-424. doi: 10.1038/s41586-020-1968-7. Epub 2020 Jan 29.
Development of an Alpha-synuclein Based Rat Model for Parkinson's Disease via Stereotactic Injection of a Recombinant Adeno-associated Viral Vector.	Van der Perren A, Casteels C, Van Laere K, Gijsbers R, Van den Haute C, Baekelandt V	J Vis Exp. 2016 Feb 28;(108):53670. doi: 10.3791/53670.
Kufor-Rakeb syndrome-associated psychosis: a novel loss-of-function ATP13A2 variant and response to antipsychotic therapy.	Colijn MA, Vrijsen S, Au PYB, Abou El Asrar R, Houdou M, Van den Haute C, Sarna J, Montgomery G, Vangheluwe P	Neurogenetics. 2024 Jul 18. doi: 10.1007/s10048-024-00767-7.
Mutated ATP10B increases Parkinson's disease risk by compromising lysosomal glucosylceramide export.	Martin S, Smolders S, Van den Haute C, Heeman B, van Veen S, Crosiers D, Beletchi I, Verstraeten A, Gossye H, Gelders G, Pals P, Hamouda NN, Engelborghs S, Martin JJ, Eggermont J, De Deyn PP, Cras P, Baekelandt V, Vangheluwe P, Van Broeckhoven C	Acta Neuropathol. 2020 Jun;139(6):1001-1024. doi: 10.1007/s00401-020-02145-7. Epub 2020 Mar 14.
Novel Green Fluorescent Polyamines to Analyze ATP13A2 and ATP13A3 Activity in the Mammalian Polyamine Transport System.	Houdou M, Jacobs N, Coene J, Azfar M, Vanhoutte R, Van den Haute C, Eggermont J, Daniels V, Verhelst SHL, Vangheluwe P	Biomolecules. 2023 Feb 9;13(2):337. doi: 10.3390/biom13020337.
The lipid flippase ATP10B enables cellular lipid uptake under stress conditions.	Wouters R, Beletchi I, Van den Haute C, Baekelandt V, Martin S, Eggermont J, Vangheluwe P	Biochim Biophys Acta Mol Cell Res. 2024 Feb;1871(2):119652. doi: 10.1016/j.bbamcr.2023.119652. Epub 2023 Dec 11.
transfer plasmid for lentiviral vector production expressing Hs ATP10B and Hs TMEM30A	(unpublished)

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	ID	Plasmid	Gene/Insert	Vector Type	Publication
	171485	pLenti HsATP13A2 WT	human ATP13A2 (ATP13A2 Human)	Lentiviral	ATP13A2 deficiency disrupts lysosomal polyamine export. Nature. 2020 Feb;578(7795):419-424. doi: 10.1038/s41586-020-1968-7. Epub 2020 Jan 29.
	171770	pLenti HsATP10B WT	ATP10B (ATP10B Human)	Lentiviral	Mutated ATP10B increases Parkinson's disease risk by compromising lysosomal glucosylceramide export. Acta Neuropathol. 2020 Jun;139(6):1001-1024. doi: 10.1007/s00401-020-02145-7. Epub 2020 Mar 14.
	171771	miR3 Mm ATP13A2	ATP13A2 (Atp13a2 Mouse)	Lentiviral	ATP13A2 deficiency disrupts lysosomal polyamine export. Nature. 2020 Feb;578(7795):419-424. doi: 10.1038/s41586-020-1968-7. Epub 2020 Jan 29.
	171789	pLenti TMEM30A	TMEM30A (TMEM30A Human)	Lentiviral	Mutated ATP10B increases Parkinson's disease risk by compromising lysosomal glucosylceramide export. Acta Neuropathol. 2020 Jun;139(6):1001-1024. doi: 10.1007/s00401-020-02145-7. Epub 2020 Mar 14.
	171790	miR2 HsATP10B	ATP10B (ATP10B Human)	Lentiviral	Mutated ATP10B increases Parkinson's disease risk by compromising lysosomal glucosylceramide export. Acta Neuropathol. 2020 Jun;139(6):1001-1024. doi: 10.1007/s00401-020-02145-7. Epub 2020 Mar 14.
	171791	miR5 MmATP10B	ATP10B (Atp10b Mouse)	Lentiviral	Mutated ATP10B increases Parkinson's disease risk by compromising lysosomal glucosylceramide export. Acta Neuropathol. 2020 Jun;139(6):1001-1024. doi: 10.1007/s00401-020-02145-7. Epub 2020 Mar 14.
	171820	pLenti HsATP13A2 D508N	human ATP13A2 (ATP13A2 Human)	Lentiviral	ATP13A2 deficiency disrupts lysosomal polyamine export. Nature. 2020 Feb;578(7795):419-424. doi: 10.1038/s41586-020-1968-7. Epub 2020 Jan 29.
	171821	pLenti HsATP13A2 D962N	human ATP13A2 (ATP13A2 Human)	Lentiviral	ATP13A2 deficiency disrupts lysosomal polyamine export. Nature. 2020 Feb;578(7795):419-424. doi: 10.1038/s41586-020-1968-7. Epub 2020 Jan 29.
	171822	miR5 Mm ATP13A2	ATP13A2 (Atp13a2 Mouse)	Lentiviral	ATP13A2 deficiency disrupts lysosomal polyamine export. Nature. 2020 Feb;578(7795):419-424. doi: 10.1038/s41586-020-1968-7. Epub 2020 Jan 29.
	171823	pLenti HsATP10B D433N	ATP10B (ATP10B Human)	Lentiviral	Mutated ATP10B increases Parkinson's disease risk by compromising lysosomal glucosylceramide export. Acta Neuropathol. 2020 Jun;139(6):1001-1024. doi: 10.1007/s00401-020-02145-7. Epub 2020 Mar 14.