Linzhao Cheng Lab Materials

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Title	Authors	Publication
A Facile Method to Establish Human Induced Pluripotent Stem Cells From Adult Blood Cells Under Feeder-Free and Xeno-Free Culture Conditions: A Clinically Compliant Approach.	Chou BK, Gu H, Gao Y, Dowey SN, Wang Y, Shi J, Li Y, Ye Z, Cheng T, Cheng L	Stem Cells Transl Med. 2015 Mar 5. pii: sctm.2014-0214.
Conditional gene knockout and reconstitution in human iPSCs with an inducible Cas9 system.	Wu M, Liu S, Gao Y, Bai H, Machairaki V, Li G, Chen T, Cheng L	Stem Cell Res. 2018 May;29:6-14. doi: 10.1016/j.scr.2018.03.003. Epub 2018 Mar 10.
Efficient human iPS cell derivation by a non-integrating plasmid from blood cells with unique epigenetic and gene expression signatures.	Chou BK, Mali P, Huang X, Ye Z, Dowey SN, Resar LM, Zou C, Zhang YA, Tong J, Cheng L	Cell Res. 2011 Jan 18. ():.
Gene targeting of a disease-related gene in human induced pluripotent stem and embryonic stem cells.	Zou J, Maeder ML, Mali P, Pruett-Miller SM, Thibodeau-Beganny S, Chou BK, Chen G, Ye Z, Park IH, Daley GQ, Porteus MH, Joung JK, Cheng L	Cell Stem Cell. 2009 Jul 2. 5(1):97-110.
HES1 inhibits cycling of hematopoietic progenitor cells via DNA binding.	Yu X, Alder JK, Chun JH, Friedman AD, Heimfeld S, Cheng L, Civin CI	Stem Cells. 2006 Apr . 24(4):876-88.
Improved efficiency and pace of generating induced pluripotent stem cells from human adult and fetal fibroblasts.	Mali P, Ye Z, Hommond HH, Yu X, Lin J, Chen G, Zou J, Cheng L	Stem Cells. 2008 Aug . 26(8):1998-2005.
Inducible and reversible transgene expression in human stem cells after efficient and stable gene transfer.	Zhou BY, Ye Z, Chen G, Gao ZP, Zhang YA, Cheng L	Stem Cells. 2007 Mar . 25(3):779-89.
Lentiviral vectors with two independent internal promoters transfer high-level expression of multiple transgenes to human hematopoietic stem-progenitor cells.	Yu X, Zhan X, D'Costa J, Tanavde VM, Ye Z, Peng T, Malehorn MT, Yang X, Civin CI, Cheng L	Mol Ther. 2003 Jun . 7(6):827-38.
Molecular imaging and stem cell research.	Jang YY, Ye Z, Cheng L	Mol Imaging. 2011 Apr;10(2):111-22.
Serial imaging of human embryonic stem-cell engraftment and teratoma formation in live mouse models.	Pomper MG, Hammond H, Yu X, Ye Z, Foss CA, Lin DD, Fox JJ, Cheng L	Cell Res. 2009 Mar;19(3):370-9.

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	ID	Plasmid	Gene/Insert	Vector Type	Publication
100.203.796007.33307	33307	Ubc.Luc.IRES.Puro	Firefly Luciferase	Mammalian Expression, Lentiviral, Luciferase	Molecular imaging and stem cell research. Mol Imaging. 2011 Apr;10(2):111-22.
100.80.923542.18922	18922	Ef1a_Large T-antigen_Ires_Puro	Large T Antigen (SV40gp6 Simian virus 40)	Mammalian Expression, Lentiviral, Cre/Lox	Improved efficiency and pace of generating induced pluripotent stem cells from human adult and fetal fibroblasts. Stem Cells. 2008 Aug . 26(8):1998-2005.
100.19.741508.24983	24983	EF.STAT3C.Ubc.GFP	STAT3 (STAT3 Human)	Mammalian Expression, Lentiviral	The high-mobility group A1a/signal transducer and activator of transcription-3 axis: an achilles heel for hematopoietic malignancies? Cancer Research 68, 10121, December 2008.
100.17.334983.17619	17619	EF.CMV.RFP		Mammalian Expression, Lentiviral	Lentiviral vectors with two independent internal promoters transfer high-level expression of multiple transgenes to human hematopoietic stem-progenitor cells. Mol Ther. 2003 Jun . 7(6):827-38.
100.14.520817.17627	17627	Duet011	UBC promoter - GFP - PGK promoter - Hygro	Mammalian Expression, Lentiviral	Inducible and reversible transgene expression in human stem cells after efficient and stable gene transfer. Stem Cells. 2007 Mar . 25(3):779-89.
100.10.208092.33308	33308	cEF.tk-GFP	HSV-TK/GFP	Mammalian Expression, Lentiviral	Serial imaging of human embryonic stem-cell engraftment and teratoma formation in live mouse models. Cell Res. 2009 Mar;19(3):370-9.
100.8.356238.17618	17618	EF.PGK.GFP		Mammalian Expression, Lentiviral	Lentiviral vectors with two independent internal promoters transfer high-level expression of multiple transgenes to human hematopoietic stem-progenitor cells. Mol Ther. 2003 Jun . 7(6):827-38.
100.4.674808.26777	26777	pEGIP	EF1a-GFP-IRES-Puro (gfp )	Mammalian Expression, Lentiviral	Gene targeting of a disease-related gene in human induced pluripotent stem and embryonic stem cells. Cell Stem Cell. 2009 Jul 2. 5(1):97-110.
100.4.515226.24984	24984	EF.STAT3DN.Ubc.GFP	STAT3 (STAT3 Human)	Mammalian Expression, Lentiviral	The high-mobility group A1a/signal transducer and activator of transcription-3 axis: an achilles heel for hematopoietic malignancies? Cancer Research 68, 10121, December 2008.
100.2.668302.28213	28213	pEB-C5	Oct4, Sox2, Klf4, c-Myc, Lin28 (Myc, Sox2, Pou5f1, Klf4, Lin28a Mouse)	Mammalian Expression	Efficient human iPS cell derivation by a non-integrating plasmid from blood cells with unique epigenetic and gene expression signatures. Cell Res. 2011 Jan 18. ():.