Klaus Rajewsky Lab Materials

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Title	Authors	Publication
Ability of the hydrophobic FGF and basic TAT peptides to promote cellular uptake of recombinant Cre recombinase: a tool for efficient genetic engineering of mammalian genomes.	Peitz M, Pfannkuche K, Rajewsky K, Edenhofer F	Proc Natl Acad Sci U S A. 2002 Apr 2. 99(7):4489-94.
Canonical NF-kappaB activity, dispensable for B cell development, replaces BAFF-receptor signals and promotes B cell proliferation upon activation.	Sasaki Y, Derudder E, Hobeika E, Pelanda R, Reth M, Rajewsky K, Schmidt-Supprian M	Immunity. 2006 Jun . 24(6):729-39.
DNA polymerase kappa deficiency does not affect somatic hypermutation in mice.	Schenten D, Gerlach VL, Guo C, Velasco-Miguel S, Hladik CL, White CL, Friedberg EC, Rajewsky K, Esposito G	Eur J Immunol. 2002 Nov . 32(11):3152-60.
Efficiency of RNA interference in the mouse hematopoietic system varies between cell types and developmental stages.	Oberdoerffer P, Kanellopoulou C, Heissmeyer V, Paeper C, Borowski C, Aifantis I, Rao A, Rajewsky K	Mol Cell Biol. 2005 May . 25(10):3896-905.
Independent control of immunoglobulin switch recombination at individual switch regions evidenced through Cre-loxP-mediated gene targeting.	Gu H, Zou YR, Rajewsky K	Cell. 1993 Jun 18. 73(6):1155-64.
LMP1 and EBNA2 constitute a minimal set of EBV genes for transformation of human B cells.	Zhang J, Sommermann T, Li X, Gieselmann L, de la Rosa K, Stecklum M, Klein F, Kocks C, Rajewsky K	Front Immunol. 2023 Dec 19;14:1331730. doi: 10.3389/fimmu.2023.1331730. eCollection 2023.
Lymphoproliferative disease and autoimmunity in mice with increased miR-17-92 expression in lymphocytes.	Xiao C, Srinivasan L, Calado DP, Patterson HC, Zhang B, Wang J, Henderson JM, Kutok JL, Rajewsky K	Nat Immunol. 2008 Apr . 9(4):405-14.
pEZ-Frt-lox-DT	(unpublished)
Precise CRISPR-Cas9 gene repair in autologous memory T cells to treat familial hemophagocytic lymphohistiocytosis.	Li X, Wirtz T, Weber T, Lebedin M, Lowenstein ED, Sommermann T, Zach A, Yasuda T, de la Rosa K, Chu VT, Schulte JH, Muller I, Kocks C, Rajewsky K	Sci Immunol. 2024 Feb 2;9(92):eadi0042. doi: 10.1126/sciimmunol.adi0042. Epub 2024 Feb 2.
Rajewsky pPGK-Cre-bpA	(unpublished)

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	ID	Plasmid	Gene/Insert	Vector Type	Publication
100.12.956573.13763	13763	pTriEx-HTNC	TAT-NLS-Cre	Bacterial Expression	Ability of the hydrophobic FGF and basic TAT peptides to promote cellular uptake of recombinant Cre recombinase: a tool for efficient genetic engineering of mammalian genomes. Proc Natl Acad Sci U S A. 2002 Apr 2. 99(7):4489-94.
100.4.441811.15912	15912	CTV	CAG-STOP-eGFP-ROSA26TV	Cre/Lox	Regulation of the germinal center response by microRNA-155. Science. 2007 Apr 27. 316(5824):604-8.
100.2.676437.11543	11543	pPGK-Cre-bpA	Phosphoglycerate kinase 1 promoter	Mammalian Expression, Cre/Lox	Rajewsky pPGK-Cre-bpA (unpublished)
100.1.079588.11739	11739	STOP-eGFP-ROSA26TV	STOP-eGFP-ROSA26TV	Cre/Lox	Canonical NF-kappaB activity, dispensable for B cell development, replaces BAFF-receptor signals and promotes B cell proliferation upon activation. Immunity. 2006 Jun . 24(6):729-39.
100.0.454208.11736	11736	pEZ-Frt-lox-DT	pEZ-Frt-lox-DT	Cre/Lox	pEZ-Frt-lox-DT (unpublished)
20.0.486397.19131	19131	pIC-Cre	Cre recombinase (cre Bacteriophage P1)	Bacterial Expression	Independent control of immunoglobulin switch recombination at individual switch regions evidenced through Cre-loxP-mediated gene targeting. Cell. 1993 Jun 18. 73(6):1155-64.
20.0.133314.11725	11725	pEasy Flox	pEasyFlox	Cre/Lox	DNA polymerase kappa deficiency does not affect somatic hypermutation in mice. Eur J Immunol. 2002 Nov . 32(11):3152-60.
	14422	pU6-STOP-shA1	modified U6 promoter (U6lox), U6 STOP cassette, shA1 gene	Mammalian Expression, RNAi, Cre/Lox	Efficiency of RNA interference in the mouse hematopoietic system varies between cell types and developmental stages. Mol Cell Biol. 2005 May . 25(10):3896-905.
	21952	pSiP1	Pten (Pten Mouse)	Mammalian Expression	Lymphoproliferative disease and autoimmunity in mice with increased miR-17-92 expression in lymphocytes. Nat Immunol. 2008 Apr . 9(4):405-14.
	21957	pSiP3	Pten (Pten Mouse)	Mammalian Expression, Luciferase	Lymphoproliferative disease and autoimmunity in mice with increased miR-17-92 expression in lymphocytes. Nat Immunol. 2008 Apr . 9(4):405-14.