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Kivanc Birsoy Lab Materials
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Log in to manage alertsTitle | Authors | Publication |
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CHP1 Regulates Compartmentalized Glycerolipid Synthesis by Activating GPAT4. | Zhu XG, Nicholson Puthenveedu S, Shen Y, La K, Ozlu C, Wang T, Klompstra D, Gultekin Y, Chi J, Fidelin J, Peng T, Molina H, Hang HC, Min W, Birsoy K | Mol Cell. 2019 Apr 4;74(1):45-58.e7. doi: 10.1016/j.molcel.2019.01.037. Epub 2019 Mar 4. |
Functional Genomics In Vivo Reveal Metabolic Dependencies of Pancreatic Cancer Cells. | Zhu XG, Chudnovskiy A, Baudrier L, Prizer B, Liu Y, Ostendorf BN, Yamaguchi N, Arab A, Tavora B, Timson R, Heissel S, de Stanchina E, Molina H, Victora GD, Goodarzi H, Birsoy K | Cell Metab. 2020 Oct 28. pii: S1550-4131(20)30550-7. doi: 10.1016/j.cmet.2020.10.017. |
Glycosphingolipid synthesis mediates immune evasion in KRAS-driven cancer. | Soula M, Unlu G, Welch R, Chudnovskiy A, Uygur B, Shah V, Alwaseem H, Bunk P, Subramanyam V, Yeh HW, Khan A, Heissel S, Goodarzi H, Victora GD, Beyaz S, Birsoy K | Nature. 2024 Aug 7. doi: 10.1038/s41586-024-07787-1. |
Integrative genetic analysis identifies FLVCR1 as a plasma-membrane choline transporter in mammals. | Kenny TC, Khan A, Son Y, Yue L, Heissel S, Sharma A, Pasolli HA, Liu Y, Gamazon ER, Alwaseem H, Hite RK, Birsoy K | Cell Metab. 2023 Jun 6;35(6):1057-1071.e12. doi: 10.1016/j.cmet.2023.04.003. Epub 2023 Apr 25. |
Metabolic-scale gene activation screens identify SLCO2B1 as a heme transporter that enhances cellular iron availability. | Unlu G, Prizer B, Erdal R, Yeh HW, Bayraktar EC, Birsoy K | Mol Cell. 2022 Aug 4;82(15):2832-2843.e7. doi: 10.1016/j.molcel.2022.05.024. Epub 2022 Jun 16. |
SLC25A39 is necessary for mitochondrial glutathione import in mammalian cells. | Wang Y, Yen FS, Zhu XG, Timson RC, Weber R, Xing C, Liu Y, Allwein B, Luo H, Yeh HW, Heissel S, Unlu G, Gamazon ER, Kharas MG, Hite R, Birsoy K | Nature. 2021 Nov;599(7883):136-140. doi: 10.1038/s41586-021-04025-w. Epub 2021 Oct 27. |
ZBTB1 Regulates Asparagine Synthesis and Leukemia Cell Response to L-Asparaginase. | Williams RT, Guarecuco R, Gates LA, Barrows D, Passarelli MC, Carey B, Baudrier L, Jeewajee S, La K, Prizer B, Malik S, Garcia-Bermudez J, Zhu XG, Cantor J, Molina H, Carroll T, Roeder RG, Abdel-Wahab O, Allis CD, Birsoy K | Cell Metab. 2020 Apr 7;31(4):852-861.e6. doi: 10.1016/j.cmet.2020.03.008. |