A Ubl/ubiquitin switch in the activation of Parkin. | Sauve V, Lilov A, Seirafi M, Vranas M, Rasool S, Kozlov G, Sprules T, Wang J, Trempe JF, Gehring K | EMBO J. 2015 Oct 14;34(20):2492-505. doi: 10.15252/embj.201592237. Epub 2015 Aug 7. |
Burst kinetics and CNNM binding are evolutionarily conserved properties of phosphatases of regenerating liver. | Fakih R, Goldstein RH, Kozlov G, Gehring K | J Biol Chem. 2023 Apr;299(4):103055. doi: 10.1016/j.jbc.2023.103055. Epub 2023 Feb 22. |
Comparative peptide binding studies of the PABC domains from the ubiquitin-protein isopeptide ligase HYD and poly(A)-binding protein. Implications for HYD function. | Lim NS, Kozlov G, Chang TC, Groover O, Siddiqui N, Volpon L, De Crescenzo G, Shyu AB, Gehring K | J Biol Chem. 2006 May 19;281(20):14376-82. doi: 10.1074/jbc.M600307200. Epub 2006 Mar 22. |
Evolution of PRL | (unpublished) | |
Mechanism of parkin activation by phosphorylation. | Sauve V, Sung G, Soya N, Kozlov G, Blaimschein N, Miotto LS, Trempe JF, Lukacs GL, Gehring K | Nat Struct Mol Biol. 2018 Jul;25(7):623-630. doi: 10.1038/s41594-018-0088-7. Epub 2018 Jul 2. |
Naturally occurring hyperactive variants of human parkin. | Huq TS, Luo J, Fakih R, Sauve V, Gehring K | Commun Biol. 2024 Aug 8;7(1):961. doi: 10.1038/s42003-024-06656-x. |
PRL3 pseudophosphatase activity is necessary and sufficient to promote metastatic growth. | Kozlov G, Funato Y, Chen YS, Zhang Z, Illes K, Miki H, Gehring K | J Biol Chem. 2020 Aug 14;295(33):11682-11692. doi: 10.1074/jbc.RA120.014464. Epub 2020 Jun 22. |
Sacsin | SIRPT1 | (unpublished) | |
Structural and Functional Study of the Phylogeny of Phosphatases of Regenerating Liver (PRL) | (unpublished) | |
Structural basis of 3'-end poly(A) RNA recognition by LARP1. | Kozlov G, Mattijssen S, Jiang J, Nyandwi S, Sprules T, Iben JR, Coon SL, Gaidamakov S, Noronha AM, Wilds CJ, Maraia RJ, Gehring K | Nucleic Acids Res. 2022 Sep 9;50(16):9534-9547. doi: 10.1093/nar/gkac696. |