Junying Yuan Lab Materials

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Title	Authors	Publication
Caspase-11 regulates cell migration by promoting Aip1-Cofilin-mediated actin depolymerization.	Li J, Brieher WM, Scimone ML, Kang SJ, Zhu H, Yin H, von Andrian UH, Mitchison T, Yuan J	Nat Cell Biol. 2007 Mar . 9(3):276-86.
Caspase-12 mediates endoplasmic-reticulum-specific apoptosis and cytotoxicity by amyloid-beta.	Nakagawa T, Zhu H, Morishima N, Li E, Xu J, Yankner BA, Yuan J	Nature. 2000 Jan 6. 403(6765):98-103.
Cleavage of BID by caspase 8 mediates the mitochondrial damage in the Fas pathway of apoptosis.	Li H, Zhu H, Xu CJ, Yuan J	Cell. 1998 Aug 21. 94(4):491-501.
Dual role of sumoylation in the nuclear localization and transcriptional activation of NFAT1.	Terui Y, Saad N, Jia S, McKeon F, Yuan J	J Biol Chem. 2004 Jul 2. 279(27):28257-65.
Flightless-I regulates proinflammatory caspases by selectively modulating intracellular localization and caspase activity.	Li J, Yin HL, Yuan J	J Cell Biol. 2008 Apr 21. 181(2):321-33.
Induction of apoptosis in fibroblasts by IL-1 beta-converting enzyme, a mammalian homolog of the C. elegans cell death gene ced-3.	Miura M, Zhu H, Rotello R, Hartwieg EA, Yuan J	Cell. 1993 Nov 19. 75(4):653-60.
Pivotal role of oligomerization in expanded polyglutamine neurodegenerative disorders.	Sanchez I, Mahlke C, Yuan J	Nature. 2003 Jan 23. 421(6921):373-9.
Regulation of intracellular accumulation of mutant Huntingtin by Beclin 1.	Shibata M, Lu T, Furuya T, Degterev A, Mizushima N, Yoshimori T, MacDonald M, Yankner B, Yuan J	J Biol Chem. 2006 May 19. 281(20):14474-85.
Regulation of RIPK1 activation by TAK1-mediated phosphorylation dictates apoptosis and necroptosis.	Geng J, Ito Y, Shi L, Amin P, Chu J, Ouchida AT, Mookhtiar AK, Zhao H, Xu D, Shan B, Najafov A, Gao G, Akira S, Yuan J	Nat Commun. 2017 Aug 25;8(1):359. doi: 10.1038/s41467-017-00406-w.
The Peutz-Jegher gene product LKB1 is a mediator of p53-dependent cell death.	Karuman P, Gozani O, Odze RD, Zhou XC, Zhu H, Shaw R, Brien TP, Bozzuto CD, Ooi D, Cantley LC, Yuan J	Mol Cell. 2001 Jun . 7(6):1307-19.

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	ID	Plasmid	Gene/Insert	Vector Type	Publication
100.128.395483.21154	21154	pcDNA3-HA-Sumo1	pcDNA3-HA-Sumo1 (SUMO1 Human)	Mammalian Expression	Dual role of sumoylation in the nuclear localization and transcriptional activation of NFAT1. J Biol Chem. 2004 Jul 2. 279(27):28257-65.
100.57.336912.21142	21142	pCMV-Caspase1-flag	caspase-1 (Casp1 Mouse)	Mammalian Expression	Flightless-I regulates proinflammatory caspases by selectively modulating intracellular localization and caspase activity. J Cell Biol. 2008 Apr 21. 181(2):321-33.
100.5.487010.21147	21147	GFP-LKB1	GFP-LKB1 (Stk11 Mouse)	Mammalian Expression	The Peutz-Jegher gene product LKB1 is a mediator of p53-dependent cell death. Mol Cell. 2001 Jun . 7(6):1307-19.
100.2.515173.21150	21150	pcDNA3-Beclin1	PcDNA3-Beclin1 (BECN1 Human)	Mammalian Expression	Regulation of intracellular accumulation of mutant Huntingtin by Beclin 1. J Biol Chem. 2006 May 19. 281(20):14474-85.
100.1.781533.21145	21145	PCMV-flag-Caspase11	Caspase11 (Casp4 Mouse)	Mammalian Expression	Caspase-11 regulates cell migration by promoting Aip1-Cofilin-mediated actin depolymerization. Nat Cell Biol. 2007 Mar . 9(3):276-86.
50.4.564650.21589	21589	GFP-ING2(pHD)	GFP-ING2(pHD) (Ing2 Mouse)	Mammalian Expression	The PHD finger of the chromatin-associated protein ING2 functions as a nuclear phosphoinositide receptor. Cell. 2003 Jul 11. 114(1):99-111.
50.2.726231.21148	21148	GFP-LKB1-KM	GFP-LKB1-KM (Stk11 Mouse)	Mammalian Expression	The Peutz-Jegher gene product LKB1 is a mediator of p53-dependent cell death. Mol Cell. 2001 Jun . 7(6):1307-19.
20.1.295215.21149	21149	pCMV-tBID	pCMV-tBID	Mammalian Expression	Cleavage of BID by caspase 8 mediates the mitochondrial damage in the Fas pathway of apoptosis. Cell. 1998 Aug 21. 94(4):491-501.
20.0.992428.21144	21144	pBabePuro-bcl2	pBabePuro-bcl 2	Mammalian Expression, Retroviral	Induction of apoptosis in fibroblasts by IL-1 beta-converting enzyme, a mammalian homolog of the C. elegans cell death gene ced-3. Cell. 1993 Nov 19. 75(4):653-60.
20.0.890922.21131	21131	pCMV-BID	flag-tagged mouse Bid	Mammalian Expression	Cleavage of BID by caspase 8 mediates the mitochondrial damage in the Fas pathway of apoptosis. Cell. 1998 Aug 21. 94(4):491-501.