Jonathan Chernoff Lab Materials

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Title	Authors	Publication
A Facile Method to Engineer Mutant Kras Alleles in an Isogenic Cell Background.	Budagyan K, Chernoff J	Methods Mol Biol. 2021;2262:323-334. doi: 10.1007/978-1-0716-1190-6_20.
H-ras Inhibits the Hippo Pathway by Promoting Mst1/Mst2 Heterodimerization.	Rawat SJ, Araiza-Olivera D, Arias-Romero LE, Villamar-Cruz O, Prudnikova TY, Roder H, Chernoff J	Curr Biol. 2016 Jun 20;26(12):1556-63. doi: 10.1016/j.cub.2016.04.027. Epub 2016 May 26.
Human p21-activated kinase (Pak1) regulates actin organization in mammalian cells.	Sells MA, Knaus UG, Bagrodia S, Ambrose DM, Bokoch GM, Chernoff J	Curr Biol. 1997 Mar 1. 7(3):202-10.
Identification of a mouse p21Cdc42/Rac activated kinase.	Bagrodia S, Taylor SJ, Creasy CL, Chernoff J, Cerione RA	J Biol Chem. 1995 Sep 29. 270(39):22731-7.
Other Pak1 plasmids	(unpublished)
p21-Activated kinase 5 (Pak5) localizes to mitochondria and inhibits apoptosis by phosphorylating BAD.	Cotteret S, Jaffer ZM, Beeser A, Chernoff J	Mol Cell Biol. 2003 Aug . 23(16):5526-39.
p21-activated kinase links Rac/Cdc42 signaling to merlin.	Xiao GH, Beeser A, Chernoff J, Testa JR	J Biol Chem. 2002 Jan 11. 277(2):883-6.
Regulation of protein tyrosine phosphatase 1B by sumoylation.	Dadke S, Cotteret S, Yip SC, Jaffer ZM, Haj F, Ivanov A, Rauscher F, Shuai K, Ng T, Neel BG, Chernoff J	Nat Cell Biol. 2007 Jan . 9(1):80-85.
The adaptor protein Nck links receptor tyrosine kinases with the serine-threonine kinase Pak1.	Galisteo ML, Chernoff J, Su YC, Skolnik EY, Schlessinger J	J Biol Chem. 1996 Aug 30. 271(35):20997-1000.
The Ste20-like protein kinase, Mst1, dimerizes and contains an inhibitory domain.	Creasy CL, Ambrose DM, Chernoff J	J Biol Chem. 1996 Aug 30. 271(35):21049-53.

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	ID	Plasmid	Gene/Insert	Vector Type	Publication
100.23.385278.12203	12203	pJ3H-Mst1	Mst1 (STK4 Human)	Mammalian Expression	The Ste20-like protein kinase, Mst1, dimerizes and contains an inhibitory domain. J Biol Chem. 1996 Aug 30. 271(35):21049-53.
100.6.128997.12208	12208	pCMV6M-PAK1 T423E	Pak1 (PAK1 Human)	Mammalian Expression	Human p21-activated kinase (Pak1) regulates actin organization in mammalian cells. Curr Biol. 1997 Mar 1. 7(3):202-10.
100.4.899068.12209	12209	pCMV6M-Pak1	Pak1 (PAK1 Human)	Mammalian Expression	Human p21-activated kinase (Pak1) regulates actin organization in mammalian cells. Curr Biol. 1997 Mar 1. 7(3):202-10.
100.4.022692.12217	12217	pGEXTK-Pak1 70-117	Pak1 (PAK1 Human)	Bacterial Expression	Other Pak1 plasmids (unpublished)
100.1.721729.12212	12212	pCMV6M-Pak1 L107F	Pak1 (PAK1 Human)	Mammalian Expression	p21-activated kinase links Rac/Cdc42 signaling to merlin. J Biol Chem. 2002 Jan 11. 277(2):883-6.
100.1.604125.12210	12210	pCMV6M-Pak1 K299R	Pak1 (PAK1 Human)	Mammalian Expression	Human p21-activated kinase (Pak1) regulates actin organization in mammalian cells. Curr Biol. 1997 Mar 1. 7(3):202-10.
50.5.862106.84293	84293	pEGFP-Merlin	Merlin (NF2) (NF2 Human)	Mammalian Expression	p21-activated kinase links Rac/Cdc42 signaling to merlin. J Biol Chem. 2002 Jan 11. 277(2):883-6.
50.1.634535.12214	12214	pEBG-Pak1 83-149	Pak1 (PAK1 Human)	Mammalian Expression	p21-activated kinase links Rac/Cdc42 signaling to merlin. J Biol Chem. 2002 Jan 11. 277(2):883-6.
50.1.312360.12204	12204	pJ3M-Mst1 K59R	Mst1 (STK4, MST1 Human)	Mammalian Expression	The Ste20-like protein kinase, Mst1, dimerizes and contains an inhibitory domain. J Biol Chem. 1996 Aug 30. 271(35):21049-53.
50.0.560181.12205	12205	pJ3M-Mst2	Mst2 (STK3 Human)	Mammalian Expression	The Ste20-like protein kinase, Mst1, dimerizes and contains an inhibitory domain. J Biol Chem. 1996 Aug 30. 271(35):21049-53.