pHL-sec Citations (24)
Originally described in: A time- and cost-efficient system for high-level protein production in mammalian cells.Aricescu AR, Lu W, Jones EY Acta Crystallogr D Biol Crystallogr. 2006 Oct;62(Pt 10):1243-50. Epub 2006 Sep 19. PubMed Journal
Articles Citing pHL-sec
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| Mapping of Adenovirus of serotype 3 fibre interaction to desmoglein 2 revealed a novel 'non-classical' mechanism of viral receptor engagement. Vassal-Stermann E, Mottet M, Ducournau C, Iseni F, Vragniau C, Wang H, Zubieta C, Lieber A, Fender P. Sci Rep. 2018 May 30;8(1):8381. doi: 10.1038/s41598-018-26871-x. PubMed |
| Antigenicity and Immunogenicity of Differentially Glycosylated Hepatitis C Virus E2 Envelope Proteins Expressed in Mammalian and Insect Cells. Urbanowicz RA, Wang R, Schiel JE, Keck ZY, Kerzic MC, Lau P, Rangarajan S, Garagusi KJ, Tan L, Guest JD, Ball JK, Pierce BG, Mariuzza RA, Foung SKH, Fuerst TR. J Virol. 2019 Mar 21;93(7). pii: JVI.01403-18. doi: 10.1128/JVI.01403-18. Print 2019 Apr 1. PubMed |
| Boosting subdominant neutralizing antibody responses with a computationally designed epitope-focused immunogen. Sesterhenn F, Galloux M, Vollers SS, Csepregi L, Yang C, Descamps D, Bonet J, Friedensohn S, Gainza P, Corthesy P, Chen M, Rosset S, Rameix-Welti MA, Eleouet JF, Reddy ST, Graham BS, Riffault S, Correia BE. PLoS Biol. 2019 Feb 21;17(2):e3000164. doi: 10.1371/journal.pbio.3000164. eCollection 2019 Feb. PubMed |
| A glycan shield on chimpanzee CD4 protects against infection by primate lentiviruses (HIV/SIV). Warren CJ, Meyerson NR, Stabell AC, Fattor WT, Wilkerson GK, Sawyer SL. Proc Natl Acad Sci U S A. 2019 Jun 4;116(23):11460-11469. doi: 10.1073/pnas.1813909116. Epub 2019 May 21. PubMed |
| Selective use of primate CD4 receptors by HIV-1. Warren CJ, Meyerson NR, Dirasantha O, Feldman ER, Wilkerson GK, Sawyer SL. PLoS Biol. 2019 Jun 10;17(6):e3000304. doi: 10.1371/journal.pbio.3000304. eCollection 2019 Jun. PubMed |
| Conformational Plasticity in the HIV-1 Fusion Peptide Facilitates Recognition by Broadly Neutralizing Antibodies. Yuan M, Cottrell CA, Ozorowski G, van Gils MJ, Kumar S, Wu NC, Sarkar A, Torres JL, de Val N, Copps J, Moore JP, Sanders RW, Ward AB, Wilson IA. Cell Host Microbe. 2019 Jun 12;25(6):873-883.e5. doi: 10.1016/j.chom.2019.04.011. PubMed |
| Binding Mechanism Elucidation of the Acute Respiratory Disease Causing Agent Adenovirus of Serotype 7 to Desmoglein-2. Hograindleur MA, Effantin G, Fenel D, Mas C, Lieber A, Schoehn G, Fender P, Vassal-Stermann E. Viruses. 2020 Sep 25;12(10). pii: v12101075. doi: 10.3390/v12101075. PubMed |
Bottom-up de novo design of functional proteins with complex structural features.
Yang C, Sesterhenn F, Bonet J, van Aalen EA, Scheller L, Abriata LA, Cramer JT, Wen X, Rosset S, Georgeon S, Jardetzky T, Krey T, Fussenegger M, Merkx M, Correia BE.
Nat Chem Biol. 2021 Apr;17(4):492-500. doi: 10.1038/s41589-020-00699-x. Epub 2021 Jan 4.
PubMed
Associated Plasmids |
| SARS-CoV-2 S protein:ACE2 interaction reveals novel allosteric targets. Raghuvamsi PV, Tulsian NK, Samsudin F, Qian X, Purushotorman K, Yue G, Kozma MM, Hwa WY, Lescar J, Bond PJ, MacAry PA, Anand GS. Elife. 2021 Feb 8;10. pii: 63646. doi: 10.7554/eLife.63646. PubMed |
| Antibody affinity as a driver of signal generation in a paper-based immunoassay for Ebola virus surveillance. Murray LP, Govindan R, Mora AC, Munro JB, Mace CR. Anal Bioanal Chem. 2021 Jun;413(14):3695-3706. doi: 10.1007/s00216-021-03317-4. Epub 2021 Apr 14. PubMed |
| Design of the SARS-CoV-2 RBD vaccine antigen improves neutralizing antibody response. Dickey TH, Tang WK, Butler B, Ouahes T, Orr-Gonzalez S, Salinas ND, Lambert LE, Tolia NH. bioRxiv. 2021 May 10. doi: 10.1101/2021.05.09.443238. PubMed |
| Selection and structural characterization of anti-TREM2 scFvs that reduce levels of shed ectodomain. Szykowska A, Chen Y, Smith TB, Preger C, Yang J, Qian D, Mukhopadhyay SM, Wigren E, Neame SJ, Graslund S, Persson H, Atkinson PJ, Di Daniel E, Mead E, Wang J, Davis JB, Burgess-Brown NA, Bullock AN. Structure. 2021 Nov 4;29(11):1241-1252.e5. doi: 10.1016/j.str.2021.06.010. Epub 2021 Jul 6. PubMed |
| AMPA receptor anchoring at CA1 synapses is determined by N-terminal domain and TARP gamma8 interactions. Watson JF, Pinggera A, Ho H, Greger IH. Nat Commun. 2021 Aug 23;12(1):5083. doi: 10.1038/s41467-021-25281-4. PubMed |
| RosettaSurf-A surface-centric computational design approach. Scheck A, Rosset S, Defferrard M, Loukas A, Bonet J, Vandergheynst P, Correia BE. PLoS Comput Biol. 2022 Mar 16;18(3):e1009178. doi: 10.1371/journal.pcbi.1009178. eCollection 2022 Mar. PubMed |
| Design of the SARS-CoV-2 RBD vaccine antigen improves neutralizing antibody response. Dickey TH, Tang WK, Butler B, Ouahes T, Orr-Gonzalez S, Salinas ND, Lambert LE, Tolia NH. Sci Adv. 2022 Sep 16;8(37):eabq8276. doi: 10.1126/sciadv.abq8276. Epub 2022 Sep 14. PubMed |
| Human immunoglobulin repertoire analysis guides design of vaccine priming immunogens targeting HIV V2-apex broadly neutralizing antibody precursors. Willis JR, Berndsen ZT, Ma KM, Steichen JM, Schiffner T, Landais E, Liguori A, Kalyuzhniy O, Allen JD, Baboo S, Omorodion O, Diedrich JK, Hu X, Georgeson E, Phelps N, Eskandarzadeh S, Groschel B, Kubitz M, Adachi Y, Mullin TM, Alavi NB, Falcone S, Himansu S, Carfi A, Wilson IA, Yates JR 3rd, Paulson JC, Crispin M, Ward AB, Schief WR. Immunity. 2022 Nov 8;55(11):2149-2167.e9. doi: 10.1016/j.immuni.2022.09.001. Epub 2022 Sep 29. PubMed |
| Biparatopic nanobodies targeting the receptor binding domain efficiently neutralize SARS-CoV-2. Pymm P, Redmond SJ, Dolezal O, Mordant F, Lopez E, Cooney JP, Davidson KC, Haycroft ER, Tan CW, Seneviratna R, Grimley SL, Purcell DFJ, Kent SJ, Wheatley AK, Wang LF, Leis A, Glukhova A, Pellegrini M, Chung AW, Subbarao K, Uldrich AP, Tham WH, Godfrey DI, Gherardin NA. iScience. 2022 Nov 18;25(11):105259. doi: 10.1016/j.isci.2022.105259. Epub 2022 Oct 4. PubMed |
| GPC3-Unc5 receptor complex structure and role in cell migration. Akkermans O, Delloye-Bourgeois C, Peregrina C, Carrasquero-Ordaz M, Kokolaki M, Berbeira-Santana M, Chavent M, Reynaud F, Raj R, Agirre J, Aksu M, White ES, Lowe E, Ben Amar D, Zaballa S, Huo J, Pakos I, McCubbin PTN, Comoletti D, Owens RJ, Robinson CV, Castellani V, Del Toro D, Seiradake E. Cell. 2022 Oct 13;185(21):3931-3949.e26. doi: 10.1016/j.cell.2022.09.025. PubMed |
| A brown fat-enriched adipokine Adissp controls adipose thermogenesis and glucose homeostasis. Chen Q, Huang L, Pan D, Hu K, Li R, Friedline RH, Kim JK, Zhu LJ, Guertin DA, Wang YX. Nat Commun. 2022 Dec 10;13(1):7633. doi: 10.1038/s41467-022-35335-w. PubMed |
| Design of a stabilized non-glycosylated Pfs48/45 antigen enables a potent malaria transmission-blocking nanoparticle vaccine. Dickey TH, Gupta R, McAleese H, Ouahes T, Orr-Gonzalez S, Ma R, Muratova O, Salinas ND, Hume JCC, Lambert LE, Duffy PE, Tolia NH. NPJ Vaccines. 2023 Feb 18;8(1):20. doi: 10.1038/s41541-023-00619-9. PubMed |
| Design of a stabilized RBD enables potently neutralizing SARS-CoV-2 single-component nanoparticle vaccines. Dickey TH, Ma R, Orr-Gonzalez S, Ouahes T, Patel P, McAleese H, Butler B, Eudy E, Eaton B, Murphy M, Kwan JL, Salinas ND, Holbrook MR, Lambert LE, Tolia NH. Cell Rep. 2023 Mar 28;42(3):112266. doi: 10.1016/j.celrep.2023.112266. Epub 2023 Mar 6. PubMed |
| Structure-based design of a strain transcending AMA1-RON2L malaria vaccine. Patel PN, Dickey TH, Diouf A, Salinas ND, McAleese H, Ouahes T, Long CA, Miura K, Lambert LE, Tolia NH. Nat Commun. 2023 Sep 2;14(1):5345. doi: 10.1038/s41467-023-40878-7. PubMed |
| Toward the understanding of DSG2 and CD46 interaction with HAdV-11 fiber, a super-complex analysis. Effantin G, Hograindleur M-A, Fenel D, Fender P, Vassal-Stermann E. J Virol. 2023 Nov 30;97(11):e0091023. doi: 10.1128/jvi.00910-23. Epub 2023 Nov 3. PubMed |
| Ebola Virus Glycoprotein Strongly Binds to Membranes in the Absence of Receptor Engagement. Vaknin A, Grossman A, Durham ND, Lupovitz I, Goren S, Golani G, Roichman Y, Munro JB, Sorkin R. ACS Infect Dis. 2024 May 10;10(5):1590-1601. doi: 10.1021/acsinfecdis.3c00622. Epub 2024 Apr 29. PubMed |
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