lenti-EF1a-dCas9-KRAB-Puro Citations (10)
Originally described in: Evaluating Synthetic Activation and Repression of Neuropsychiatric-Related Genes in hiPSC-Derived NPCs, Neurons, and Astrocytes.Ho SM, Hartley BJ, Flaherty E, Rajarajan P, Abdelaal R, Obiorah I, Barretto N, Muhammad H, Phatnani HP, Akbarian S, Brennand KJ Stem Cell Reports. 2017 Aug 8;9(2):615-628. doi: 10.1016/j.stemcr.2017.06.012. Epub 2017 Jul 27. PubMed Journal
Articles Citing lenti-EF1a-dCas9-KRAB-Puro
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| Three-dimensional analysis of single molecule FISH in human colon organoids. Omerzu M, Fenderico N, de Barbanson B, Sprangers J, de Ridder J, Maurice MM. Biol Open. 2019 Aug 9;8(8). pii: bio.042812. doi: 10.1242/bio.042812. PubMed |
| A rare variant of African ancestry activates 8q24 lncRNA hub by modulating cancer associated enhancer. Walavalkar K, Saravanan B, Singh AK, Jayani RS, Nair A, Farooq U, Islam Z, Soota D, Mann R, Shivaprasad PV, Freedman ML, Sabarinathan R, Haiman CA, Notani D. Nat Commun. 2020 Jul 17;11(1):3598. doi: 10.1038/s41467-020-17325-y. PubMed |
| Transformative Network Modeling of Multi-omics Data Reveals Detailed Circuits, Key Regulators, and Potential Therapeutics for Alzheimer's Disease. Wang M, Li A, Sekiya M, Beckmann ND, Quan X, Schrode N, Fernando MB, Yu A, Zhu L, Cao J, Lyu L, Horgusluoglu E, Wang Q, Guo L, Wang YS, Neff R, Song WM, Wang E, Shen Q, Zhou X, Ming C, Ho SM, Vatansever S, Kaniskan HU, Jin J, Zhou MM, Ando K, Ho L, Slesinger PA, Yue Z, Zhu J, Katsel P, Gandy S, Ehrlich ME, Fossati V, Noggle S, Cai D, Haroutunian V, Iijima KM, Schadt E, Brennand KJ, Zhang B. Neuron. 2021 Jan 20;109(2):257-272.e14. doi: 10.1016/j.neuron.2020.11.002. Epub 2020 Nov 24. PubMed |
Neurodevelopmental defects and neurodegenerative phenotypes in human brain organoids carrying Parkinson's disease-linked DNAJC6 mutations.
Wulansari N, Darsono WHW, Woo HJ, Chang MY, Kim J, Bae EJ, Sun W, Lee JH, Cho IJ, Shin H, Lee SJ, Lee SH.
Sci Adv. 2021 Feb 17;7(8). pii: 7/8/eabb1540. doi: 10.1126/sciadv.abb1540. Print 2021 Feb.
PubMed
Associated Plasmids |
| Using the dCas9-KRAB system to repress gene expression in hiPSC-derived NGN2 neurons. Li A, Cartwright S, Yu A, Ho SM, Schrode N, Deans PJM, Matos MR, Garcia MF, Townsley KG, Zhang B, Brennand KJ. STAR Protoc. 2021 Jun 3;2(2):100580. doi: 10.1016/j.xpro.2021.100580. eCollection 2021 Jun 18. PubMed |
| Transforming growth factor-beta challenge alters the N-, O-, and glycosphingolipid glycomes in PaTu-S pancreatic adenocarcinoma cells. Zhang J, Zhang Z, Holst S, Blochl C, Madunic K, Wuhrer M, Ten Dijke P, Zhang T. J Biol Chem. 2022 Mar;298(3):101717. doi: 10.1016/j.jbc.2022.101717. Epub 2022 Feb 11. PubMed |
| Active enhancers strengthen insulation by RNA-mediated CTCF binding at chromatin domain boundaries. Islam Z, Saravanan B, Walavalkar K, Farooq U, Singh AK, Radhakrishnan S, Thakur J, Pandit A, Henikoff S, Notani D. Genome Res. 2023 Jan;33(1):1-17. doi: 10.1101/gr.276643.122. Epub 2023 Jan 17. PubMed |
| Development of a CRISPRi Human Retinal Pigmented Epithelium Model for Functional Study of Age-Related Macular Degeneration Genes. Wang JH, Urrutia-Cabrera D, Lees JG, Mesa Mora S, Nguyen T, Hung SSC, Hewitt AW, Lim SY, Edwards TL, Wong RCB. Int J Mol Sci. 2023 Feb 8;24(4):3417. doi: 10.3390/ijms24043417. PubMed |
| A biallelic multiple nucleotide length polymorphism explains functional causality at 5p15.33 prostate cancer risk locus. Spisak S, Tisza V, Nuzzo PV, Seo JH, Pataki B, Ribli D, Sztupinszki Z, Bell C, Rohanizadegan M, Stillman DR, Alaiwi SA, Bartels AH, Papp M, Shetty A, Abbasi F, Lin X, Lawrenson K, Gayther SA, Pomerantz M, Baca S, Solymosi N, Csabai I, Szallasi Z, Gusev A, Freedman ML. Nat Commun. 2023 Aug 23;14(1):5118. doi: 10.1038/s41467-023-40616-z. PubMed |
| Germline cis variant determines epigenetic regulation of the anti-cancer drug metabolism gene dihydropyrimidine dehydrogenase (DPYD). Zhang T, Ambrodji A, Huang H, Bouchonville KJ, Etheridge AS, Schmidt RE, Bembenek BM, Temesgen ZB, Wang Z, Innocenti F, Stroka D, Diasio RB, Largiader CR, Offer SM. Elife. 2024 Apr 30;13:RP94075. doi: 10.7554/eLife.94075. PubMed |
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