MBP-FUS_FL_WT Citations (17)
Originally described in: Residue-by-Residue View of In Vitro FUS Granules that Bind the C-Terminal Domain of RNA Polymerase II.Burke KA, Janke AM, Rhine CL, Fawzi NL Mol Cell. 2015 Oct 15;60(2):231-41. doi: 10.1016/j.molcel.2015.09.006. Epub 2015 Oct 8. PubMed Journal
Articles Citing MBP-FUS_FL_WT
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| SARS-CoV-2 nucleocapsid protein undergoes liquid-liquid phase separation stimulated by RNA and partitions into phases of human ribonucleoproteins. Perdikari TM, Murthy AC, Ryan VH, Watters S, Naik MT, Fawzi NL. bioRxiv. 2020 Jun 10. doi: 10.1101/2020.06.09.141101. PubMed |
| The prion-like domain of Fused in Sarcoma is phosphorylated by multiple kinases affecting liquid- and solid-phase transitions. Owen I, Rhoads S, Yee D, Wyne H, Gery K, Hannula I, Sundrum M, Shewmaker F. Mol Biol Cell. 2020 Nov 1;31(23):2522-2536. doi: 10.1091/mbc.E20-05-0290. Epub 2020 Sep 2. PubMed |
| Small molecules as potent biphasic modulators of protein liquid-liquid phase separation. Babinchak WM, Dumm BK, Venus S, Boyko S, Putnam AA, Jankowsky E, Surewicz WK. Nat Commun. 2020 Nov 4;11(1):5574. doi: 10.1038/s41467-020-19211-z. PubMed |
SARS-CoV-2 nucleocapsid protein phase-separates with RNA and with human hnRNPs.
Perdikari TM, Murthy AC, Ryan VH, Watters S, Naik MT, Fawzi NL.
EMBO J. 2020 Nov 17:e106478. doi: 10.15252/embj.2020106478.
PubMed
Associated Plasmids |
| High-fidelity reconstitution of stress granules and nucleoli in mammalian cellular lysate. Freibaum BD, Messing J, Yang P, Kim HJ, Taylor JP. J Cell Biol. 2021 Mar 1;220(3). pii: 211726. doi: 10.1083/jcb.202009079. PubMed |
| A modular tool to query and inducibly disrupt biomolecular condensates. Hernandez-Candia CN, Pearce S, Tucker CL. Nat Commun. 2021 Mar 22;12(1):1809. doi: 10.1038/s41467-021-22096-1. PubMed |
| Characterization of design grammar of peptides for regulating liquid droplets and aggregates of FUS. Kamagata K, Chiba R, Kawahata I, Iwaki N, Kanbayashi S, Maeda K, Takahashi H, Hirano A, Fukunaga K, Ikeda K, Kameda T. Sci Rep. 2021 Mar 23;11(1):6643. doi: 10.1038/s41598-021-86098-1. PubMed |
| Interactions between ALS-linked FUS and nucleoporins are associated with defects in the nucleocytoplasmic transport pathway. Lin YC, Kumar MS, Ramesh N, Anderson EN, Nguyen AT, Kim B, Cheung S, McDonough JA, Skarnes WC, Lopez-Gonzalez R, Landers JE, Fawzi NL, Mackenzie IRA, Lee EB, Nickerson JA, Grunwald D, Pandey UB, Bosco DA. Nat Neurosci. 2021 Aug;24(8):1077-1088. doi: 10.1038/s41593-021-00859-9. Epub 2021 May 31. PubMed |
| FUS-ALS mutants alter FMRP phase separation equilibrium and impair protein translation. Birsa N, Ule AM, Garone MG, Tsang B, Mattedi F, Chong PA, Humphrey J, Jarvis S, Pisiren M, Wilkins OG, Nosella ML, Devoy A, Bodo C, de la Fuente RF, Fisher EMC, Rosa A, Viero G, Forman-Kay JD, Schiavo G, Fratta P. Sci Adv. 2021 Jul 21;7(30):eabf8660. doi: 10.1126/sciadv.abf8660. Print 2021 Jul. PubMed |
| The oncogenic transcription factor FUS-CHOP can undergo nuclear liquid-liquid phase separation. Owen I, Yee D, Wyne H, Perdikari TM, Johnson V, Smyth J, Kortum R, Fawzi NL, Shewmaker F. J Cell Sci. 2021 Sep 1;134(17). pii: 272045. doi: 10.1242/jcs.258578. Epub 2021 Sep 3. PubMed |
| Molecular interactions contributing to FUS SYGQ LC-RGG phase separation and co-partitioning with RNA polymerase II heptads. Murthy AC, Tang WS, Jovic N, Janke AM, Seo DH, Perdikari TM, Mittal J, Fawzi NL. Nat Struct Mol Biol. 2021 Nov;28(11):923-935. doi: 10.1038/s41594-021-00677-4. Epub 2021 Nov 10. PubMed |
| Rational peptide design for regulating liquid-liquid phase separation on the basis of residue-residue contact energy. Kamagata K, Ariefai M, Takahashi H, Hando A, Subekti DRG, Ikeda K, Hirano A, Kameda T. Sci Rep. 2022 Aug 12;12(1):13718. doi: 10.1038/s41598-022-17829-1. PubMed |
| A spatiotemporal reconstruction of the C. elegans pharyngeal cuticle reveals a structure rich in phase-separating proteins. Kamal M, Tokmakjian L, Knox J, Mastrangelo P, Ji J, Cai H, Wojciechowski JW, Hughes MP, Takacs K, Chu X, Pei J, Grolmusz V, Kotulska M, Forman-Kay JD, Roy PJ. Elife. 2022 Oct 19;11:e79396. doi: 10.7554/eLife.79396. PubMed |
| Fused in sarcoma undergoes cold denaturation: Implications for phase separation. Felix SS, Laurents DV, Oroz J, Cabrita EJ. Protein Sci. 2023 Jan;32(1):e4521. doi: 10.1002/pro.4521. PubMed |
| Defining RNA oligonucleotides that reverse deleterious phase transitions of RNA-binding proteins with prion-like domains. Guo L, Mann JR, Mauna JC, Copley KE, Wang H, Rubien JD, Odeh HM, Lin J, Lee BL, Ganser L, Robinson E, Kim KM, Murthy AC, Paul T, Portz B, Gleixner AM, Diaz Z, Carey JL, Smirnov A, Padilla G, Lavorando E, Espy C, Shang Y, Huang EJ, Chesi A, Fawzi NL, Myong S, Donnelly CJ, Shorter J. bioRxiv [Preprint]. 2023 Sep 4:2023.09.04.555754. doi: 10.1101/2023.09.04.555754. PubMed |
A platform to induce and mature biomolecular condensates using chemicals and light.
Hernandez-Candia CN, Brady BR, Harrison E, Tucker CL.
Nat Chem Biol. 2024 Jan 8. doi: 10.1038/s41589-023-01520-1.
PubMed
Associated Plasmids |
| Transcription Factor Condensates Mediate Clustering of MET Regulon and Enhancement in Gene Expression. Lee J, Simpson L, Li Y, Becker S, Zou F, Zhang X, Bai L. bioRxiv [Preprint]. 2024 Jul 12:2024.02.06.579062. doi: 10.1101/2024.02.06.579062. PubMed |
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