lentiCRISPRv2 hygro Citations (39)
Originally described in: A reference collection of patient-derived cell line and xenograft models of proneural, classical and mesenchymal glioblastoma.Stringer BW, Day BW, D'Souza RCJ, Jamieson PR, Ensbey KS, Bruce ZC, Lim YC, Goasdoue K, Offenhauser C, Akgul S, Allan S, Robertson T, Lucas P, Tollesson G, Campbell S, Winter C, Do H, Dobrovic A, Inglis PL, Jeffree RL, Johns TG, Boyd AW Sci Rep. 2019 Mar 20;9(1):4902. doi: 10.1038/s41598-019-41277-z. PubMed Journal
Articles Citing lentiCRISPRv2 hygro
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| Discovery of a small molecule targeting autophagy via ATG4B inhibition and cell death of colorectal cancer cells in vitro and in vivo. Fu Y, Hong L, Xu J, Zhong G, Gu Q, Gu Q, Guan Y, Zheng X, Dai Q, Luo X, Liu C, Huang Z, Yin XM, Liu P, Li M. Autophagy. 2019 Feb;15(2):295-311. doi: 10.1080/15548627.2018.1517073. Epub 2018 Sep 20. PubMed |
| METTL13 Methylation of eEF1A Increases Translational Output to Promote Tumorigenesis. Liu S, Hausmann S, Carlson SM, Fuentes ME, Francis JW, Pillai R, Lofgren SM, Hulea L, Tandoc K, Lu J, Li A, Nguyen ND, Caporicci M, Kim MP, Maitra A, Wang H, Wistuba II, Porco JA Jr, Bassik MC, Elias JE, Song J, Topisirovic I, Van Rechem C, Mazur PK, Gozani O. Cell. 2019 Jan 24;176(3):491-504.e21. doi: 10.1016/j.cell.2018.11.038. Epub 2019 Jan 3. PubMed |
Depletion of TRRAP induces p53-independent senescence in liver cancer by downregulating mitotic genes.
Kwan SY, Sheel A, Song CQ, Zhang XO, Jiang T, Dang H, Cao Y, Ozata DM, Mou H, Yin H, Weng Z, Wang XW, Xue W.
Hepatology. 2019 Jun 12. doi: 10.1002/hep.30807.
PubMed
Associated Plasmids |
| BCAA catabolism in brown fat controls energy homeostasis through SLC25A44. Yoneshiro T, Wang Q, Tajima K, Matsushita M, Maki H, Igarashi K, Dai Z, White PJ, McGarrah RW, Ilkayeva OR, Deleye Y, Oguri Y, Kuroda M, Ikeda K, Li H, Ueno A, Ohishi M, Ishikawa T, Kim K, Chen Y, Sponton CH, Pradhan RN, Majd H, Greiner VJ, Yoneshiro M, Brown Z, Chondronikola M, Takahashi H, Goto T, Kawada T, Sidossis L, Szoka FC, McManus MT, Saito M, Soga T, Kajimura S. Nature. 2019 Aug;572(7771):614-619. doi: 10.1038/s41586-019-1503-x. Epub 2019 Aug 21. PubMed |
| The CoQ oxidoreductase FSP1 acts parallel to GPX4 to inhibit ferroptosis. Bersuker K, Hendricks JM, Li Z, Magtanong L, Ford B, Tang PH, Roberts MA, Tong B, Maimone TJ, Zoncu R, Bassik MC, Nomura DK, Dixon SJ, Olzmann JA. Nature. 2019 Nov;575(7784):688-692. doi: 10.1038/s41586-019-1705-2. Epub 2019 Oct 21. PubMed |
| Three-dimensional bioprinted glioblastoma microenvironments model cellular dependencies and immune interactions. Tang M, Xie Q, Gimple RC, Zhong Z, Tam T, Tian J, Kidwell RL, Wu Q, Prager BC, Qiu Z, Yu A, Zhu Z, Mesci P, Jing H, Schimelman J, Wang P, Lee D, Lorenzini MH, Dixit D, Zhao L, Bhargava S, Miller TE, Wan X, Tang J, Sun B, Cravatt BF, Muotri AR, Chen S, Rich JN. Cell Res. 2020 Jun 4. pii: 10.1038/s41422-020-0338-1. doi: 10.1038/s41422-020-0338-1. PubMed |
| Trinucleotide Repeat-Targeting dCas9 as a Therapeutic Strategy for Fuchs' Endothelial Corneal Dystrophy. Rong Z, Gong X, Hulleman JD, Corey DR, Mootha VV. Transl Vis Sci Technol. 2020 Aug 31;9(9):47. doi: 10.1167/tvst.9.9.47. eCollection 2020 Aug. PubMed |
| Peroxisomal-derived ether phospholipids link nucleotides to respirasome assembly. Bennett CF, O'Malley KE, Perry EA, Balsa E, Latorre-Muro P, Riley CL, Luo C, Jedrychowski M, Gygi SP, Puigserver P. Nat Chem Biol. 2021 Jun;17(6):703-710. doi: 10.1038/s41589-021-00772-z. Epub 2021 Mar 15. PubMed |
| The inhibitory receptor TIM-3 limits activation of the cGAS-STING pathway in intra-tumoral dendritic cells by suppressing extracellular DNA uptake. de Mingo Pulido A, Hanggi K, Celias DP, Gardner A, Li J, Batista-Bittencourt B, Mohamed E, Trillo-Tinoco J, Osunmakinde O, Pena R, Onimus A, Kaisho T, Kaufmann J, McEachern K, Soliman H, Luca VC, Rodriguez PC, Yu X, Ruffell B. Immunity. 2021 Jun 8;54(6):1154-1167.e7. doi: 10.1016/j.immuni.2021.04.019. Epub 2021 May 11. PubMed |
| Tumor-Associated Macrophage Promotes the Survival of Cancer Cells upon Docetaxel Chemotherapy via the CSF1/CSF1R-CXCL12/CXCR4 Axis in Castration-Resistant Prostate Cancer. Guan W, Li F, Zhao Z, Zhang Z, Hu J, Zhang Y. Genes (Basel). 2021 May 19;12(5). pii: genes12050773. doi: 10.3390/genes12050773. PubMed |
| Gain-of-function p53(R172H) mutation drives accumulation of neutrophils in pancreatic tumors, promoting resistance to immunotherapy. Siolas D, Vucic E, Kurz E, Hajdu C, Bar-Sagi D. Cell Rep. 2021 Aug 24;36(8):109578. doi: 10.1016/j.celrep.2021.109578. PubMed |
| INK4 Tumor Suppressor Proteins Mediate Resistance to CDK4/6 Kinase Inhibitors. Li Q, Jiang B, Guo J, Shao H, Del Priore IS, Chang Q, Kudo R, Li Z, Razavi P, Liu B, Boghossian AS, Rees MG, Ronan MM, Roth JA, Donovan KA, Palafox M, Reis-Filho JS, de Stanchina E, Fischer ES, Rosen N, Serra V, Koff A, Chodera JD, Gray NS, Chandarlapaty S. Cancer Discov. 2022 Feb;12(2):356-371. doi: 10.1158/2159-8290.CD-20-1726. Epub 2021 Sep 20. PubMed |
| Herpes simplex virus 1 evades cellular antiviral response by inducing microRNA-24, which attenuates STING synthesis. Sharma N, Wang C, Kessler P, Sen GC. PLoS Pathog. 2021 Sep 30;17(9):e1009950. doi: 10.1371/journal.ppat.1009950. eCollection 2021 Sep. PubMed |
| Labeling and measuring stressed mitochondria using a PINK1-based ratiometric fluorescent sensor. Uesugi R, Ishii S, Matsuura A, Itakura E. J Biol Chem. 2021 Nov;297(5):101279. doi: 10.1016/j.jbc.2021.101279. Epub 2021 Oct 5. PubMed |
| Activation of the NRF2 antioxidant program sensitizes tumors to G6PD inhibition. Ding H, Chen Z, Wu K, Huang SM, Wu WL, LeBoeuf SE, Pillai RG, Rabinowitz JD, Papagiannakopoulos T. Sci Adv. 2021 Nov 19;7(47):eabk1023. doi: 10.1126/sciadv.abk1023. Epub 2021 Nov 17. PubMed |
| STAG2 regulates interferon signaling in melanoma via enhancer loop reprogramming. Chu Z, Gu L, Hu Y, Zhang X, Li M, Chen J, Teng D, Huang M, Shen CH, Cai L, Yoshida T, Qi Y, Niu Z, Feng A, Geng S, Frederick DT, Specht E, Piris A, Sullivan RJ, Flaherty KT, Boland GM, Georgopoulos K, Liu D, Shi Y, Zheng B. Nat Commun. 2022 Apr 6;13(1):1859. doi: 10.1038/s41467-022-29541-9. PubMed |
| The nuclear receptor ERR cooperates with the cardiogenic factor GATA4 to orchestrate cardiomyocyte maturation. Sakamoto T, Batmanov K, Wan S, Guo Y, Lai L, Vega RB, Kelly DP. Nat Commun. 2022 Apr 13;13(1):1991. doi: 10.1038/s41467-022-29733-3. PubMed |
| ADAM10 and ADAM17 promote SARS-CoV-2 cell entry and spike protein-mediated lung cell fusion. Jocher G, Grass V, Tschirner SK, Riepler L, Breimann S, Kaya T, Oelsner M, Hamad MS, Hofmann LI, Blobel CP, Schmidt-Weber CB, Gokce O, Jakwerth CA, Trimpert J, Kimpel J, Pichlmair A, Lichtenthaler SF. EMBO Rep. 2022 Jun 7;23(6):e54305. doi: 10.15252/embr.202154305. Epub 2022 May 8. PubMed |
| Androgen and oestrogen receptor co-expression determines the efficacy of hormone receptor-mediated radiosensitisation in breast cancer. Michmerhuizen AR, Lerner LM, Ward C, Pesch AM, Zhang A, Schwartz R, Wilder-Romans K, Eisner JR, Rae JM, Pierce LJ, Speers CW. Br J Cancer. 2022 Sep;127(5):927-936. doi: 10.1038/s41416-022-01849-9. Epub 2022 May 26. PubMed |
| Ribosome stalling during selenoprotein translation exposes a ferroptosis vulnerability. Li Z, Ferguson L, Deol KK, Roberts MA, Magtanong L, Hendricks JM, Mousa GA, Kilinc S, Schaefer K, Wells JA, Bassik MC, Goga A, Dixon SJ, Ingolia NT, Olzmann JA. Nat Chem Biol. 2022 Jul;18(7):751-761. doi: 10.1038/s41589-022-01033-3. Epub 2022 May 30. PubMed |
| ORAI1-Regulated Gene Expression in Breast Cancer Cells: Roles for STIM1 Binding, Calcium Influx and Transcription Factor Translocation. Robitaille M, Chan SM, Peters AA, Dai L, So CL, Bong AHL, Sadras F, Roberts-Thomson SJ, Monteith GR. Int J Mol Sci. 2022 May 24;23(11). pii: ijms23115867. doi: 10.3390/ijms23115867. PubMed |
| Cancer-associated fibroblasts employ NUFIP1-dependent autophagy to secrete nucleosides and support pancreatic tumor growth. Yuan M, Tu B, Li H, Pang H, Zhang N, Fan M, Bai J, Wang W, Shu Z, DuFort CC, Huo S, Zhai J, Yao K, Wang L, Ying H, Zhu WG, Fu D, Hu Z, Zhao Y. Nat Cancer. 2022 Aug;3(8):945-960. doi: 10.1038/s43018-022-00426-6. Epub 2022 Aug 18. PubMed |
| Liquid-liquid phase separation facilitates the biogenesis of secretory storage granules. Parchure A, Tian M, Stalder D, Boyer CK, Bearrows SC, Rohli KE, Zhang J, Rivera-Molina F, Ramazanov BR, Mahata SK, Wang Y, Stephens SB, Gershlick DC, von Blume J. J Cell Biol. 2022 Dec 5;221(12):e202206132. doi: 10.1083/jcb.202206132. Epub 2022 Sep 29. PubMed |
| Bcl-xL inhibition radiosensitizes PIK3CA/PTEN wild-type triple negative breast cancers with low Mcl-1 expression. Pesch AM, Chandler BC, Michmerhuizen AR, Carter HM, Hirsh NH, Wilder-Romans K, Liu M, Ward T, Ritter CL, Nino CA, Jungles KM, Pierce LJ, Rae JM, Speers CW. Cancer Res Commun. 2022 Jul;2(7):679-693. doi: 10.1158/2767-9764.crc-22-0024. Epub 2022 Jul 20. PubMed |
| Cullin-5 deficiency orchestrates the tumor microenvironment to promote mammary tumor development through CREB1-CCL2 signaling. Chen S, Shao F, Zeng J, Guo S, Wang L, Sun H, Lei JH, Lyu X, Gao S, Chen Q, Miao K, Xu X, Deng CX. Sci Adv. 2023 Jan 20;9(3):eabq1395. doi: 10.1126/sciadv.abq1395. Epub 2023 Jan 20. PubMed |
| CCPG1 recognizes endoplasmic reticulum luminal proteins for selective ER-phagy. Ishii S, Chino H, Ode KL, Kurikawa Y, Ueda HR, Matsuura A, Mizushima N, Itakura E. Mol Biol Cell. 2023 Apr 1;34(4):ar29. doi: 10.1091/mbc.E22-09-0432. Epub 2023 Feb 3. PubMed |
| Antagonism between Prdm16 and Smad4 specifies the trajectory and progression of pancreatic cancer. Hurwitz E, Parajuli P, Ozkan S, Prunier C, Nguyen TL, Campbell D, Friend C, Bryan AA, Lu TX, Smith SC, Razzaque MS, Xu K, Atfi A. J Cell Biol. 2023 Apr 3;222(4):e202203036. doi: 10.1083/jcb.202203036. Epub 2023 Feb 24. PubMed |
Hominoid SVA-lncRNA AK057321 targets human-specific SVA retrotransposons in SCN8A and CDK5RAP2 to initiate neuronal maturation.
Nadler MJS, Chang W, Ozkaynak E, Huo Y, Nong Y, Boillot M, Johnson M, Moreno A, Matthew P Anderson.
Commun Biol. 2023 Mar 30;6(1):347. doi: 10.1038/s42003-023-04683-8.
PubMed
Associated Plasmids |
| Identification of structurally diverse FSP1 inhibitors that sensitize cancer cells to ferroptosis. Hendricks JM, Doubravsky CE, Wehri E, Li Z, Roberts MA, Deol KK, Lange M, Lasheras-Otero I, Momper JD, Dixon SJ, Bersuker K, Schaletzky J, Olzmann JA. Cell Chem Biol. 2023 May 4:S2451-9456(23)00114-9. doi: 10.1016/j.chembiol.2023.04.007. PubMed |
| Pluripotency-independent induction of human trophoblast stem cells from fibroblasts. Naama M, Rahamim M, Zayat V, Sebban S, Radwan A, Orzech D, Lasry R, Ifrah A, Jaber M, Sabag O, Yassen H, Khatib A, Epsztejn-Litman S, Novoselsky-Persky M, Makedonski K, Deri N, Goldman-Wohl D, Cedar H, Yagel S, Eiges R, Buganim Y. Nat Commun. 2023 Jun 8;14(1):3359. doi: 10.1038/s41467-023-39104-1. PubMed |
| Break-induced replication orchestrates resection-dependent template switching. Zhang T, Rawal Y, Jiang H, Kwon Y, Sung P, Greenberg RA. Nature. 2023 Jul;619(7968):201-208. doi: 10.1038/s41586-023-06177-3. Epub 2023 Jun 14. PubMed |
| Fanconi anemia DNA crosslink repair factors protect against LINE-1 retrotransposition during mouse development. Bona N, Crossan GP. Nat Struct Mol Biol. 2023 Oct;30(10):1434-1445. doi: 10.1038/s41594-023-01067-8. Epub 2023 Aug 14. PubMed |
| Desmoplastic stroma restricts T cell extravasation and mediates immune exclusion and immunosuppression in solid tumors. Xiao Z, Todd L, Huang L, Noguera-Ortega E, Lu Z, Huang L, Kopp M, Li Y, Pattada N, Zhong W, Guo W, Scholler J, Liousia M, Assenmacher CA, June CH, Albelda SM, Pure E. Nat Commun. 2023 Aug 22;14(1):5110. doi: 10.1038/s41467-023-40850-5. PubMed |
| Cell fusion upregulates PD-L1 expression for evasion from immunosurveillance. Tajima Y, Shibasaki F, Masai H. Cancer Gene Ther. 2024 Jan;31(1):158-173. doi: 10.1038/s41417-023-00693-0. Epub 2023 Nov 21. PubMed |
| FAM86A methylation of eEF2 links mRNA translation elongation to tumorigenesis. Francis JW, Hausmann S, Ikram S, Yin K, Mealey-Farr R, Flores NM, Trinh AT, Chasan T, Thompson J, Mazur PK, Gozani O. Mol Cell. 2024 May 2;84(9):1753-1763.e7. doi: 10.1016/j.molcel.2024.02.037. Epub 2024 Mar 19. PubMed |
| The SPATA5-SPATA5L1 ATPase complex directs replisome proteostasis to ensure genome integrity. Krishnamoorthy V, Foglizzo M, Dilley RL, Wu A, Datta A, Dutta P, Campbell LJ, Degtjarik O, Musgrove LJ, Calabrese AN, Zeqiraj E, Greenberg RA. Cell. 2024 Apr 25;187(9):2250-2268.e31. doi: 10.1016/j.cell.2024.03.002. Epub 2024 Mar 29. PubMed |
| Cellular geometry and epithelial-mesenchymal plasticity intersect with PIEZO1 in breast cancer cells. So CL, Robitaille M, Sadras F, McCullough MH, Milevskiy MJG, Goodhill GJ, Roberts-Thomson SJ, Monteith GR. Commun Biol. 2024 Apr 17;7(1):467. doi: 10.1038/s42003-024-06163-z. PubMed |
| Hippo-YAP/TAZ signalling coordinates adipose plasticity and energy balance by uncoupling leptin expression from fat mass. Choi S, Kang JG, Tran YTH, Jeong SH, Park KY, Shin H, Kim YH, Park M, Nahmgoong H, Seol T, Jeon H, Kim Y, Park S, Kim HJ, Kim MS, Li X, Bou Sleiman M, Lee E, Choi J, Eisenbarth D, Lee SH, Cho S, Moore DD, Auwerx J, Kim IY, Kim JB, Park JE, Lim DS, Suh JM. Nat Metab. 2024 May;6(5):847-860. doi: 10.1038/s42255-024-01045-4. Epub 2024 May 29. PubMed |
| Gain-of-function human UNC93B1 variants cause systemic lupus erythematosus and chilblain lupus. David C, Arango-Franco CA, Badonyi M, Fouchet J, Rice GI, Didry-Barca B, Maisonneuve L, Seabra L, Kechiche R, Masson C, Cobat A, Abel L, Talouarn E, Beziat V, Deswarte C, Livingstone K, Paul C, Malik G, Ross A, Adam J, Walsh J, Kumar S, Bonnet D, Bodemer C, Bader-Meunier B, Marsh JA, Casanova JL, Crow YJ, Manoury B, Fremond ML, Bohlen J, Lepelley A. J Exp Med. 2024 Aug 5;221(8):e20232066. doi: 10.1084/jem.20232066. Epub 2024 Jun 13. PubMed |
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