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TetO-Ascl1-puro Citations (13)

Originally described in: Generation of pure GABAergic neurons by transcription factor programming.
Yang N, Chanda S, Marro S, Ng YH, Janas JA, Haag D, Ang CE, Tang Y, Flores Q, Mall M, Wapinski O, Li M, Ahlenius H, Rubenstein JL, Chang HY, Buylla AA, Sudhof TC, Wernig M Nat Methods. 2017 May 15. doi: 10.1038/nmeth.4291.
PubMed Journal

Articles Citing TetO-Ascl1-puro

Articles
Rapid and efficient induction of functional astrocytes from human pluripotent stem cells. Canals I, Ginisty A, Quist E, Timmerman R, Fritze J, Miskinyte G, Monni E, Hansen MG, Hidalgo I, Bryder D, Bengzon J, Ahlenius H. Nat Methods. 2018 Sep;15(9):693-696. doi: 10.1038/s41592-018-0103-2. Epub 2018 Aug 20. PubMed

Associated Plasmids

Transcription factor programming of human ES cells generates functional neurons expressing both upper and deep layer cortical markers. Miskinyte G, Gronning Hansen M, Monni E, Lam M, Bengzon J, Lindvall O, Ahlenius H, Kokaia Z. PLoS One. 2018 Oct 11;13(10):e0204688. doi: 10.1371/journal.pone.0204688. eCollection 2018. PubMed
ASCL1- and DLX2-induced GABAergic neurons from hiPSC-derived NPCs. Barretto N, Zhang H, Powell SK, Fernando MB, Zhang S, Flaherty EK, Ho SM, Slesinger PA, Duan J, Brennand KJ. J Neurosci Methods. 2020 Feb 14;334:108548. doi: 10.1016/j.jneumeth.2019.108548. PubMed
Cell Type-Specific In Vitro Gene Expression Profiling of Stem Cell-Derived Neural Models. Gregory JA, Hoelzli E, Abdelaal R, Braine C, Cuevas M, Halpern M, Barretto N, Schrode N, Akbalik G, Kang K, Cheng E, Bowles K, Lotz S, Goderie S, Karch CM, Temple S, Goate A, Brennand KJ, Phatnani H. Cells. 2020 Jun 5;9(6). pii: cells9061406. doi: 10.3390/cells9061406. PubMed

Associated Plasmids

Transcription Factor Programming of Human Pluripotent Stem Cells to Functionally Mature Astrocytes for Monocultures and Cocultures with Neurons. Quist E, Ahlenius H, Canals I. Methods Mol Biol. 2021;2352:133-148. doi: 10.1007/978-1-0716-1601-7_10. PubMed
Induction of dopaminergic neurons for neuronal subtype-specific modeling of psychiatric disease risk. Powell SK, O'Shea C, Townsley K, Prytkova I, Dobrindt K, Elahi R, Iskhakova M, Lambert T, Valada A, Liao W, Ho SM, Slesinger PA, Huckins LM, Akbarian S, Brennand KJ. Mol Psychiatry. 2021 Sep 7. pii: 10.1038/s41380-021-01273-0. doi: 10.1038/s41380-021-01273-0. PubMed

Associated Plasmids

Human stem cell-derived GABAergic neurons functionally integrate into human neuronal networks. Gonzalez-Ramos A, Waloschkova E, Mikroulis A, Kokaia Z, Bengzon J, Ledri M, Andersson M, Kokaia M. Sci Rep. 2021 Nov 11;11(1):22050. doi: 10.1038/s41598-021-01270-x. PubMed
Publicly Available hiPSC Lines with Extreme Polygenic Risk Scores for Modeling Schizophrenia. Dobrindt K, Zhang H, Das D, Abdollahi S, Prorok T, Ghosh S, Weintraub S, Genovese G, Powell SK, Lund A, Akbarian S, Eggan K, McCarroll S, Duan J, Avramopoulos D, Brennand KJ. Complex Psychiatry. 2021 Feb;6(3-4):68-82. doi: 10.1159/000512716. Epub 2020 Nov 2. PubMed
Mapping cis-regulatory elements in human neurons links psychiatric disease heritability and activity-regulated transcriptional programs. Sanchez-Priego C, Hu R, Boshans LL, Lalli M, Janas JA, Williams SE, Dong Z, Yang N. Cell Rep. 2022 May 31;39(9):110877. doi: 10.1016/j.celrep.2022.110877. PubMed
Pharmacological chaperones restore proteostasis of epilepsy-associated GABA (A) receptor variants. Wang YJ, Seibert H, Ahn LY, Schaffer AE, Mu TW. bioRxiv. 2023 Apr 19:2023.04.18.537383. doi: 10.1101/2023.04.18.537383. Preprint. PubMed
Schizophrenia Risk Mapping and Functional Engineering of the 3D Genome in Three Neuronal Subtypes. Powell SK, Liao W, O'Shea C, Kammourh S, Ghorbani S, Rigat R, Elahi R, Deans PM, Le DJ, Agarwal P, Seow WQ, Wang KC, Akbarian S, Brennand KJ. bioRxiv. 2023 Jul 19:2023.07.17.549339. doi: 10.1101/2023.07.17.549339. Preprint. PubMed
Precise Therapeutic Targeting of Distinct NRXN1(+/-) Mutations. Fernando MB, Fan Y, Zhang Y, Kammourh S, Murphy AN, Ghorbani S, Onatzevitch R, Pero A, Padilla C, Flaherty EK, Prytkova IK, Cao L, Williams S, Fang G, Slesinger PA, Brennand KJ. bioRxiv [Preprint]. 2023 Dec 23:2023.10.28.564543. doi: 10.1101/2023.10.28.564543. PubMed
Defined co-cultures of glutamatergic and GABAergic neurons with a mutation in DISC1 reveal aberrant phenotypes in GABAergic neurons. Heider J, Stahl A, Sperlich D, Hartmann SM, Vogel S, Breitmeyer R, Templin M, Volkmer H. BMC Neurosci. 2024 Mar 4;25(1):12. doi: 10.1186/s12868-024-00858-z. PubMed

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