pLEX_305-C-dTAG Citations (9)
Originally described in: The dTAG system for immediate and target-specific protein degradation.Nabet B, Roberts JM, Buckley DL, Paulk J, Dastjerdi S, Yang A, Leggett AL, Erb MA, Lawlor MA, Souza A, Scott TG, Vittori S, Perry JA, Qi J, Winter GE, Wong KK, Gray NS, Bradner JE Nat Chem Biol. 2018 May;14(5):431-441. doi: 10.1038/s41589-018-0021-8. Epub 2018 Mar 26. PubMed Journal
Articles Citing pLEX_305-C-dTAG
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| Selective Modulation of a Pan-Essential Protein as a Therapeutic Strategy in Cancer. Malone CF, Dharia NV, Kugener G, Forman AB, Rothberg MV, Abdusamad M, Gonzalez A, Kuljanin M, Robichaud AL, Conway AS, Dempster JM, Paolella BR, Dumont N, Hovestadt V, Mancias JD, Younger ST, Root DE, Golub TR, Vazquez F, Stegmaier K. Cancer Discov. 2021 Sep;11(9):2282-2299. doi: 10.1158/2159-8290.CD-20-1213. Epub 2021 Apr 21. PubMed |
VRK1 as a synthetic lethal target in VRK2 promoter-methylated cancers of the nervous system.
So J, Mabe NW, Englinger B, Chow KH, Moyer SM, Yerrum S, Trissal MC, Marques JG, Kwon JJ, Shim B, Pal S, Panditharatna E, Quinn T, Schaefer DA, Jeong D, Mayhew DL, Hwang J, Beroukhim R, Ligon KL, Stegmaier K, Filbin MG, Hahn WC.
JCI Insight. 2022 Oct 10;7(19):e158755. doi: 10.1172/jci.insight.158755.
PubMed
Associated Plasmids |
| The ETS transcription factor ETV6 constrains the transcriptional activity of EWS-FLI to promote Ewing sarcoma. Lu DY, Ellegast JM, Ross KN, Malone CF, Lin S, Mabe NW, Dharia NV, Meyer A, Conway A, Su AH, Selich-Anderson J, Taslim C, Byrum AK, Seong BKA, Adane B, Gray NS, Rivera MN, Lessnick SL, Stegmaier K. Nat Cell Biol. 2023 Feb;25(2):285-297. doi: 10.1038/s41556-022-01059-8. Epub 2023 Jan 19. PubMed |
Recovery of protein synthesis to assay DNA repair activity in transcribed genes in living cells and tissues.
van der Woude M, Davo-Martinez C, Thijssen KL, Vermeulen W, Lans H.
Nucleic Acids Res. 2023 Oct 13;51(18):e93. doi: 10.1093/nar/gkad642.
PubMed
Associated Plasmids |
| The SMN complex drives structural changes in human snRNAs to enable snRNP assembly. Panek J, Roithova A, Radivojevic N, Sykora M, Prusty AB, Huston N, Wan H, Pyle AM, Fischer U, Stanek D. Nat Commun. 2023 Oct 18;14(1):6580. doi: 10.1038/s41467-023-42324-0. PubMed |
| Harnessing PROTAC technology to combat stress hormone receptor activation. Gazorpak M, Hugentobler KM, Paul D, Germain PL, Kretschmer M, Ivanova I, Frei S, Mathis K, Rudolf R, Mompart Barrenechea S, Fischer V, Xue X, Ptaszek AL, Holzinger J, Privitera M, Hierlemann A, Meijer OC, Konrat R, Carreira EM, Bohacek J, Gapp K. Nat Commun. 2023 Dec 9;14(1):8177. doi: 10.1038/s41467-023-44031-2. PubMed |
| CXCL16-dependent scavenging of oxidized lipids by islet macrophages promotes differentiation of pathogenic CD8(+) T cells in diabetic autoimmunity. Srivastava N, Hu H, Peterson OJ, Vomund AN, Stremska M, Zaman M, Giri S, Li T, Lichti CF, Zakharov PN, Zhang B, Abumrad NA, Chen YG, Ravichandran KS, Unanue ER, Wan X. Immunity. 2024 Jul 9;57(7):1629-1647.e8. doi: 10.1016/j.immuni.2024.04.017. Epub 2024 May 15. PubMed |
| The KAT module of the SAGA complex maintains the oncogenic gene expression program in MYCN-amplified neuroblastoma. Malone CF, Mabe NW, Forman AB, Alexe G, Engel KL, Chen YC, Soeung M, Salhotra S, Basanthakumar A, Liu B, Dent SYR, Stegmaier K. Sci Adv. 2024 May 31;10(22):eadm9449. doi: 10.1126/sciadv.adm9449. Epub 2024 May 31. PubMed |
| Transcriptional synergy in human aortic endothelial cells is vulnerable to combination p300/CBP and BET bromodomain inhibition. Bracken RC, Davison LM, Buehler DP, Fulton ME, Carson EE, Sheng Q, Stolze LK, Guillermier C, Steinhauser ML, Brown JD. iScience. 2024 May 16;27(6):110011. doi: 10.1016/j.isci.2024.110011. eCollection 2024 Jun 21. PubMed |
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