pBABE puro K-Ras V12 Citations (25)
Originally described in: Viral vectors.Unpublished
Articles Citing pBABE puro K-Ras V12
| Articles |
|---|
| Regulation of u-PAR gene expression by H2A.Z is modulated by the MEK-ERK/AP-1 pathway. Chauhan S, Boyd DD. Nucleic Acids Res. 2012 Jan;40(2):600-13. doi: 10.1093/nar/gkr725. Epub 2011 Sep 21. PubMed |
| Elevated expression of Fn14 in non-small cell lung cancer correlates with activated EGFR and promotes tumor cell migration and invasion. Whitsett TG, Cheng E, Inge L, Asrani K, Jameson NM, Hostetter G, Weiss GJ, Kingsley CB, Loftus JC, Bremner R, Tran NL, Winkles JA. Am J Pathol. 2012 Jul;181(1):111-20. doi: 10.1016/j.ajpath.2012.03.026. Epub 2012 May 23. PubMed |
| K-Ras and B-Raf oncogenes inhibit colon epithelial polarity establishment through up-regulation of c-myc. Magudia K, Lahoz A, Hall A. J Cell Biol. 2012 Jul 23;198(2):185-94. doi: 10.1083/jcb.201202108. PubMed |
| Atorvastatin overcomes gefitinib resistance in KRAS mutant human non-small cell lung carcinoma cells. Chen J, Bi H, Hou J, Zhang X, Zhang C, Yue L, Wen X, Liu D, Shi H, Yuan J, Liu J, Liu B. Cell Death Dis. 2013 Sep 26;4:e814. doi: 10.1038/cddis.2013.312. PubMed |
| ARF triggers senescence in Brca2-deficient cells by altering the spectrum of p53 transcriptional targets. Carlos AR, Escandell JM, Kotsantis P, Suwaki N, Bouwman P, Badie S, Folio C, Benitez J, Gomez-Lopez G, Pisano DG, Jonkers J, Tarsounas M. Nat Commun. 2013;4:2697. doi: 10.1038/ncomms3697. PubMed |
| CD52 is a molecular target in advanced systemic mastocytosis. Hoermann G, Blatt K, Greiner G, Putz EM, Berger A, Herrmann H, Cerny-Reiterer S, Gleixner KV, Walz C, Hoetzenecker K, Mullauer L, Reiter A, Sotlar K, Sexl V, Valent P, Mayerhofer M. FASEB J. 2014 Aug;28(8):3540-51. doi: 10.1096/fj.14-250894. Epub 2014 Apr 23. PubMed |
MutT Homolog 1 (MTH1) maintains multiple KRAS-driven pro-malignant pathways.
Patel A, Burton DG, Halvorsen K, Balkan W, Reiner T, Perez-Stable C, Cohen A, Munoz A, Giribaldi MG, Singh S, Robbins DJ, Nguyen DM, Rai P.
Oncogene. 2015 May 14;34(20):2586-96. doi: 10.1038/onc.2014.195. Epub 2014 Jul 14.
PubMed
Associated Plasmids |
| AKT regulates NPM dependent ARF localization and p53mut stability in tumors. Hamilton G, Abraham AG, Morton J, Sampson O, Pefani DE, Khoronenkova S, Grawenda A, Papaspyropoulos A, Jamieson N, McKay C, Sansom O, Dianov GL, O'Neill E. Oncotarget. 2014 Aug 15;5(15):6142-67. PubMed |
| Oncogenic PI3K and K-Ras stimulate de novo lipid synthesis through mTORC1 and SREBP. Ricoult SJ, Yecies JL, Ben-Sahra I, Manning BD. Oncogene. 2015 Jun 1. doi: 10.1038/onc.2015.179. PubMed |
| Synergistic induction of apoptosis by salinomycin and gefitinib through lysosomal and mitochondrial dependent pathway overcomes gefitinib resistance in colorectal cancer. Zou ZZ, Nie PP, Li YW, Hou BX, Rui-Li, Shi XP, Ma ZK, Han BW, Luo XY. Oncotarget. 2017 Apr 4;8(14):22414-22432. doi: 10.18632/oncotarget.5628. PubMed |
| The mucin MUC4 is a transcriptional and post-transcriptional target of K-ras oncogene in pancreatic cancer. Implication of MAPK/AP-1, NF-kappaB and RalB signaling pathways. Vasseur R, Skrypek N, Duchene B, Renaud F, Martinez-Maqueda D, Vincent A, Porchet N, Van Seuningen I, Jonckheere N. Biochim Biophys Acta. 2015 Dec;1849(12):1375-84. doi: 10.1016/j.bbagrm.2015.10.014. Epub 2015 Oct 22. PubMed |
| Catabolic pathways regulated by mTORC1 are pivotal for survival and growth of cancer cells expressing mutant Ras. Sung S, Choi J, Cheong H. Oncotarget. 2015 Dec 1;6(38):40405-17. doi: 10.18632/oncotarget.6334. PubMed |
| Autophagy is required for PDAC glutamine metabolism. Seo JW, Choi J, Lee SY, Sung S, Yoo HJ, Kang MJ, Cheong H, Son J. Sci Rep. 2016 Nov 28;6:37594. doi: 10.1038/srep37594. PubMed |
| Context-Dependent Epigenetic Regulation of Nuclear Factor of Activated T Cells 1 in Pancreatic Plasticity. Chen NM, Neesse A, Dyck ML, Steuber B, Koenig AO, Lubeseder-Martellato C, Winter T, Forster T, Bohnenberger H, Kitz J, Reuter-Jessen K, Griesmann H, Gaedcke J, Grade M, Zhang JS, Tsai WC, Siveke J, Schildhaus HU, Strobel P, Johnsen SA, Ellenrieder V, Hessmann E. Gastroenterology. 2017 May;152(6):1507-1520.e15. doi: 10.1053/j.gastro.2017.01.043. Epub 2017 Feb 8. PubMed |
| Multivalent Small-Molecule Pan-RAS Inhibitors. Welsch ME, Kaplan A, Chambers JM, Stokes ME, Bos PH, Zask A, Zhang Y, Sanchez-Martin M, Badgley MA, Huang CS, Tran TH, Akkiraju H, Brown LM, Nandakumar R, Cremers S, Yang WS, Tong L, Olive KP, Ferrando A, Stockwell BR. Cell. 2017 Feb 23;168(5):878-889.e29. doi: 10.1016/j.cell.2017.02.006. PubMed |
| Reconstituting development of pancreatic intraepithelial neoplasia from primary human pancreas duct cells. Lee J, Snyder ER, Liu Y, Gu X, Wang J, Flowers BM, Kim YJ, Park S, Szot GL, Hruban RH, Longacre TA, Kim SK. Nat Commun. 2017 Mar 8;8:14686. doi: 10.1038/ncomms14686. PubMed |
| PKM1 Confers Metabolic Advantages and Promotes Cell-Autonomous Tumor Cell Growth. Morita M, Sato T, Nomura M, Sakamoto Y, Inoue Y, Tanaka R, Ito S, Kurosawa K, Yamaguchi K, Sugiura Y, Takizaki H, Yamashita Y, Katakura R, Sato I, Kawai M, Okada Y, Watanabe H, Kondoh G, Matsumoto S, Kishimoto A, Obata M, Matsumoto M, Fukuhara T, Motohashi H, Suematsu M, Komatsu M, Nakayama KI, Watanabe T, Soga T, Shima H, Maemondo M, Tanuma N. Cancer Cell. 2018 Mar 12;33(3):355-367.e7. doi: 10.1016/j.ccell.2018.02.004. PubMed |
| Endogenous IQGAP1 and IQGAP3 do not functionally interact with Ras. Morgan CJ, Hedman AC, Li Z, Sacks DB. Sci Rep. 2019 Jul 30;9(1):11057. doi: 10.1038/s41598-019-46677-9. PubMed |
| Synergistic effect of fasting-mimicking diet and vitamin C against KRAS mutated cancers. Di Tano M, Raucci F, Vernieri C, Caffa I, Buono R, Fanti M, Brandhorst S, Curigliano G, Nencioni A, de Braud F, Longo VD. Nat Commun. 2020 May 11;11(1):2332. doi: 10.1038/s41467-020-16243-3. PubMed |
| Targeting sphingosine kinase 1 (SK1) enhances oncogene-induced senescence through ceramide synthase 2 (CerS2)-mediated generation of very-long-chain ceramides. Trayssac M, Clarke CJ, Stith JL, Snider JM, Newen N, Gault CR, Hannun YA, Obeid LM. Cell Death Dis. 2021 Jan 4;12(1):27. doi: 10.1038/s41419-020-03281-4. PubMed |
| p21 produces a bioactive secretome that places stressed cells under immunosurveillance. Sturmlechner I, Zhang C, Sine CC, van Deursen EJ, Jeganathan KB, Hamada N, Grasic J, Friedman D, Stutchman JT, Can I, Hamada M, Lim DY, Lee JH, Ordog T, Laberge RM, Shapiro V, Baker DJ, Li H, van Deursen JM. Science. 2021 Oct 29;374(6567):eabb3420. doi: 10.1126/science.abb3420. Epub 2021 Oct 29. PubMed |
| Domain-specific p53 mutants activate EGFR by distinct mechanisms exposing tissue-independent therapeutic vulnerabilities. Ho TLF, Lee MY, Goh HC, Ng GYN, Lee JJH, Kannan S, Lim YT, Zhao T, Lim EKH, Phua CZJ, Lee YF, Lim RYX, Ng PJH, Yuan J, Chan DKH, Lieske B, Chong CS, Lee KC, Lum J, Cheong WK, Yeoh KG, Tan KK, Sobota RM, Verma CS, Lane DP, Tam WL, Venkitaraman AR. Nat Commun. 2023 Mar 28;14(1):1726. doi: 10.1038/s41467-023-37223-3. PubMed |
| Optogenetic modulation of guanine nucleotide exchange factors of Ras superfamily proteins directly controls cell shape and movement. Pal DS, Lin Y, Zhan H, Banerjee T, Kuhn J, Providence S, Devreotes PN. Front Cell Dev Biol. 2023 Jul 10;11:1195806. doi: 10.3389/fcell.2023.1195806. eCollection 2023. PubMed |
| Akt enhances the vulnerability of cancer cells to VCP/p97 inhibition-mediated paraptosis. Lee DM, Kim IY, Lee HJ, Seo MJ, Cho MY, Lee HI, Yoon G, Ji JH, Park SS, Jeong SY, Choi EK, Choi YH, Yun CO, Yeo M, Kim E, Choi KS. Cell Death Dis. 2024 Jan 13;15(1):48. doi: 10.1038/s41419-024-06434-x. PubMed |
| Oncogenic K-Ras(G12V) cannot overcome proliferation failure caused by loss of Ppp6c in mouse embryonic fibroblasts. Ito M, Tanuma N, Kotani Y, Murai K, Kondo A, Sumiyoshi M, Shima H, Matsuda S, Watanabe T. FEBS Open Bio. 2024 Apr;14(4):545-554. doi: 10.1002/2211-5463.13775. Epub 2024 Feb 6. PubMed |
If you have published an article using this material, please email us at [email protected] to have your article added to this page.