1014 pcDNA3 T7 Akt1 K179M T308A S473A Citations (10)

Originally described in: Regulation of G1 progression by the PTEN tumor suppressor protein is linked to inhibition of the phosphatidylinositol 3-kinase/Akt pathway.
Ramaswamy S, Nakamura N, Vazquez F, Batt DB, Perera S, Roberts TM, Sellers WR Proc Natl Acad Sci U S A. 1999 Mar 2. 96(5):2110-5. PubMed Journal

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Articles Citing 1014 pcDNA3 T7 Akt1 K179M T308A S473A

Articles
Rapamycin-mediated FOXO1 inactivation reduces the anticancer efficacy of rapamycin. Abdelnour-Berchtold E, Cerantola Y, Roulin D, Dormond-Meuwly A, Demartines N, Dormond O. Anticancer Res. 2010 Mar;30(3):799-804. PubMed
Essential role of PI3-kinase pathway in p53-mediated transcription: Implications in cancer chemotherapy. Suvasini R, Somasundaram K. Oncogene. 2010 Jun 24;29(25):3605-18. doi: 10.1038/onc.2010.123. Epub 2010 Apr 26. PubMed
Loss of IGFBP7 expression and persistent AKT activation contribute to SMARCB1/Snf5-mediated tumorigenesis. Darr J, Klochendler A, Isaac S, Eden A. Oncogene. 2014 Jun 5;33(23):3024-32. doi: 10.1038/onc.2013.261. Epub 2013 Jul 15. PubMed
Selective regulation of axonal growth from developing hippocampal neurons by tumor necrosis factor superfamily member APRIL. Osorio C, Chacon PJ, White M, Kisiswa L, Wyatt S, Rodriguez-Tebar A, Davies AM. Mol Cell Neurosci. 2014 Mar;59:24-36. doi: 10.1016/j.mcn.2014.01.002. Epub 2014 Jan 18. PubMed
Enhanced myeloid differentiation factor 88 promotes tumor metastasis via induction of epithelial-mesenchymal transition in human hepatocellular carcinoma. Jia RJ, Cao L, Zhang L, Jing W, Chen R, Zhu MH, Guo SW, Wu GB, Fan XY, Wang H, Zhang YY, Zhou XY, Zhao J, Guo YJ. Cell Death Dis. 2014 Mar 6;5:e1103. doi: 10.1038/cddis.2014.71. PubMed
PI3K/mTORC2 regulates TGF-beta/Activin signalling by modulating Smad2/3 activity via linker phosphorylation. Yu JS, Ramasamy TS, Murphy N, Holt MK, Czapiewski R, Wei SK, Cui W. Nat Commun. 2015 May 22;6:7212. doi: 10.1038/ncomms8212. PubMed
Nuclear Localization of DNAJB6 Is Associated With Survival of Patients With Esophageal Cancer and Reduces AKT Signaling and Proliferation of Cancer Cells. Yu VZ, Wong VC, Dai W, Ko JM, Lam AK, Chan KW, Samant RS, Lung HL, Shuen WH, Law S, Chan YP, Lee NP, Tong DK, Law TT, Lee VH, Lung ML. Gastroenterology. 2015 Dec;149(7):1825-1836.e5. doi: 10.1053/j.gastro.2015.08.025. Epub 2015 Aug 22. PubMed
BECN1/Beclin 1 sorts cell-surface APP/amyloid beta precursor protein for lysosomal degradation. Swaminathan G, Zhu W, Plowey ED. Autophagy. 2016 Dec;12(12):2404-2419. Epub 2016 Oct 7. PubMed
Akt phosphorylation regulated by IKKepsilon in response to low shear stress leads to endothelial inflammation via activating IRF3. Zhu L, Yang H, Chao Y, Gu Y, Zhang J, Wang F, Yu W, Ye P, Chu P, Kong X, Chen S. Cell Signal. 2021 Apr;80:109900. doi: 10.1016/j.cellsig.2020.109900. Epub 2020 Dec 25. PubMed
A growth-factor-activated lysosomal K(+) channel regulates Parkinson's pathology. Wie J, Liu Z, Song H, Tropea TF, Yang L, Wang H, Liang Y, Cang C, Aranda K, Lohmann J, Yang J, Lu B, Chen-Plotkin AS, Luk KC, Ren D. Nature. 2021 Mar;591(7850):431-437. doi: 10.1038/s41586-021-03185-z. Epub 2021 Jan 27. PubMed

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