1013 pcDNA3 T7 Akt1 T308A S473A Citations (4)
Originally described in: Regulation of G1 progression by the PTEN tumor suppressor protein is linked to inhibition of the phosphatidylinositol 3-kinase/Akt pathway.Ramaswamy S, Nakamura N, Vazquez F, Batt DB, Perera S, Roberts TM, Sellers WR Proc Natl Acad Sci U S A. 1999 Mar 2. 96(5):2110-5. PubMed Journal
Articles Citing 1013 pcDNA3 T7 Akt1 T308A S473A
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t-Darpp promotes cancer cell survival by up-regulation of Bcl2 through Akt-dependent mechanism. Belkhiri A, Dar AA, Zaika A, Kelley M, El-Rifai W. Cancer Res. 2008 Jan 15;68(2):395-403. doi: 10.1158/0008-5472.CAN-07-1580. PubMed |
The endogenous inhibitor of Akt, CTMP, is critical to ischemia-induced neuronal death. Miyawaki T, Ofengeim D, Noh KM, Latuszek-Barrantes A, Hemmings BA, Follenzi A, Zukin RS. Nat Neurosci. 2009 May;12(5):618-26. doi: 10.1038/nn.2299. Epub 2009 Apr 6. PubMed |
Oncogenic cooperation between PI3K/Akt signaling and transcription factor Runx2 promotes the invasive properties of metastatic breast cancer cells. Pande S, Browne G, Padmanabhan S, Zaidi SK, Lian JB, van Wijnen AJ, Stein JL, Stein GS. J Cell Physiol. 2013 Aug;228(8):1784-92. doi: 10.1002/jcp.24339. PubMed |
TCTP protein degradation by targeting mTORC1 and signaling through S6K, Akt, and Plk1 sensitizes lung cancer cells to DNA-damaging drugs. Jeong M, Jeong MH, Kim JE, Cho S, Lee KJ, Park S, Sohn J, Park YG. Sci Rep. 2021 Oct 21;11(1):20812. doi: 10.1038/s41598-021-00247-0. PubMed |
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