1236 pcDNA3 Myr HA Akt3 Citations (21)
Originally described in: AktUnpublished
Articles Citing 1236 pcDNA3 Myr HA Akt3
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| Role of a novel PH-kinase domain interface in PKB/Akt regulation: structural mechanism for allosteric inhibition. Calleja V, Laguerre M, Parker PJ, Larijani B. PLoS Biol. 2009 Jan 20;7(1):e17. doi: 10.1371/journal.pbio.1000017. PubMed |
| Synthesis and evaluation of indazole based analog sensitive Akt inhibitors. Okuzumi T, Ducker GS, Zhang C, Aizenstein B, Hoffman R, Shokat KM. Mol Biosyst. 2010 Aug;6(8):1389-402. doi: 10.1039/c003917a. Epub 2010 Jun 28. PubMed |
| Role of the C-terminal regulatory domain in the allosteric inhibition of PKB/Akt. Calleja V, Laguerre M, Larijani B. Adv Biol Regul. 2012 Jan;52(1):46-57. PubMed |
| PI(4,5)P2 5-phosphatase A regulates PI3K/Akt signalling and has a tumour suppressive role in human melanoma. Ye Y, Jin L, Wilmott JS, Hu WL, Yosufi B, Thorne RF, Liu T, Rizos H, Yan XG, Dong L, Tay KH, Tseng HY, Guo ST, de Bock CE, Jiang CC, Wang CY, Wu M, Zhang LJ, Hersey P, Scolyer RA, Zhang XD. Nat Commun. 2013;4:1508. doi: 10.1038/ncomms2489. PubMed |
| Loss of PI(4,5)P2 5-Phosphatase A Contributes to Resistance of Human Melanoma Cells to RAF/MEK Inhibitors. Ye Y, Li Q, Hu WL, Tseng HY, Jin L, Zhang XD, Zhang LJ, Yang S. Transl Oncol. 2013 Aug 1;6(4):470-81. Print 2013 Aug. PubMed |
| The adherens junction protein afadin is an AKT substrate that regulates breast cancer cell migration. Elloul S, Kedrin D, Knoblauch NW, Beck AH, Toker A. Mol Cancer Res. 2014 Mar;12(3):464-76. doi: 10.1158/1541-7786.MCR-13-0398. Epub 2013 Nov 22. PubMed |
| MDM2-mediated degradation of SIRT6 phosphorylated by AKT1 promotes tumorigenesis and trastuzumab resistance in breast cancer. Thirumurthi U, Shen J, Xia W, LaBaff AM, Wei Y, Li CW, Chang WC, Chen CH, Lin HK, Yu D, Hung MC. Sci Signal. 2014 Jul 29;7(336):ra71. doi: 10.1126/scisignal.2005076. PubMed |
| The activity of the anti-apoptotic fragment generated by the caspase-3/p120 RasGAP stress-sensing module displays strict Akt isoform specificity. Vanli G, Peltzer N, Dubuis G, Widmann C. Cell Signal. 2014 Dec;26(12):2992-7. doi: 10.1016/j.cellsig.2014.09.009. Epub 2014 Sep 22. PubMed |
| Function of the chondrocyte PI-3 kinase-Akt signaling pathway is stimulus dependent. Greene MA, Loeser RF. Osteoarthritis Cartilage. 2015 Jun;23(6):949-56. doi: 10.1016/j.joca.2015.01.014. Epub 2015 Feb 3. PubMed |
| PTEN regulates IGF-1R mediated therapy resistance in melanoma. Wang J, Sinnberg T, Niessner H, Dolker R, Sauer B, Kempf WE, Meier F, Leslie N, Schittek B. Pigment Cell Melanoma Res. 2015 Jun 26. doi: 10.1111/pcmr.12390. PubMed |
| Suppression of SHIP2 contributes to tumorigenesis and proliferation of gastric cancer cells via activation of Akt. Ye Y, Ge YM, Xiao MM, Guo LM, Li Q, Hao JQ, Da J, Hu WL, Zhang XD, Xu J, Zhang LJ. J Gastroenterol. 2015 Jul 23. PubMed |
| PI3K-Akt signaling pathway upregulates hepatitis C virus RNA translation through the activation of SREBPs. Shi Q, Hoffman B, Liu Q. Virology. 2016 Mar;490:99-108. doi: 10.1016/j.virol.2016.01.012. Epub 2016 Feb 6. PubMed |
| mTORC1 is necessary but mTORC2 and GSK3beta are inhibitory for AKT3-induced axon regeneration in the central nervous system. Miao L, Yang L, Huang H, Liang F, Ling C, Hu Y. Elife. 2016 Mar 30;5. pii: e14908. doi: 10.7554/eLife.14908. PubMed |
| Regulation of miRNA-29c and its downstream pathways in preneoplastic progression of triple-negative breast cancer. Bhardwaj A, Singh H, Rajapakshe K, Tachibana K, Ganesan N, Pan Y, Gunaratne PH, Coarfa C, Bedrosian I. Oncotarget. 2017 Mar 21;8(12):19645-19660. doi: 10.18632/oncotarget.14902. PubMed |
| Dual function of the PI3K-Akt-mTORC1 axis in myelination of the peripheral nervous system. Figlia G, Norrmen C, Pereira JA, Gerber D, Suter U. Elife. 2017 Sep 7;6. doi: 10.7554/eLife.29241. PubMed |
| HDAC inhibitors restore BRAF-inhibitor sensitivity by altering PI3K and survival signalling in a subset of melanoma. Gallagher SJ, Gunatilake D, Beaumont KA, Sharp DM, Tiffen JC, Heinemann A, Weninger W, Haass NK, Wilmott JS, Madore J, Ferguson PM, Rizos H, Hersey P. Int J Cancer. 2018 May 1;142(9):1926-1937. doi: 10.1002/ijc.31199. Epub 2017 Dec 20. PubMed |
| The Wnt Signaling Pathway Is Differentially Expressed during the Bovine Herpesvirus 1 Latency-Reactivation Cycle: Evidence That Two Protein Kinases Associated with Neuronal Survival, Akt3 and BMPR2, Are Expressed at Higher Levels during Latency. Workman A, Zhu L, Keel BN, Smith TPL, Jones C. J Virol. 2018 Mar 14;92(7). pii: JVI.01937-17. doi: 10.1128/JVI.01937-17. Print 2018 Apr 1. PubMed |
| AKT3 Gene Transfer Promotes Anabolic Reprogramming and Photoreceptor Neuroprotection in a Pre-clinical Model of Retinitis Pigmentosa. McDougald DS, Papp TE, Zezulin AU, Zhou S, Bennett J. Mol Ther. 2019 Jul 3;27(7):1313-1326. doi: 10.1016/j.ymthe.2019.04.009. Epub 2019 Apr 14. PubMed |
| Specific Akt Family Members Impair Stress-Mediated Transactivation of Viral Promoters and Enhance Neuronal Differentiation: Important Functions for Maintaining Latency. Zhao J, Zhu L, Wijesekera N, Jones C. J Virol. 2020 Oct 14;94(21). pii: JVI.00901-20. doi: 10.1128/JVI.00901-20. Print 2020 Oct 14. PubMed |
| AKT1 mediates multiple phosphorylation events that functionally promote HSF1 activation. Lu WC, Omari R, Ray H, Wang J, Williams I, Jacobs C, Hockaden N, Bochman ML, Carpenter RL. FEBS J. 2022 Jul;289(13):3876-3893. doi: 10.1111/febs.16375. Epub 2022 Feb 11. PubMed |
| Substrate preference of protein kinase B isoforms can vary depending on the cell line. Palma MS, Perez SR, Husain A, Bhandari D. PLoS One. 2024 Mar 19;19(3):e0298322. doi: 10.1371/journal.pone.0298322. eCollection 2024. PubMed |
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