896 pcDNA3 T7 Akt1 Citations (9)
Originally described in: Regulation of G1 progression by the PTEN tumor suppressor protein is linked to inhibition of the phosphatidylinositol 3-kinase/Akt pathway.Ramaswamy S, Nakamura N, Vazquez F, Batt DB, Perera S, Roberts TM, Sellers WR Proc Natl Acad Sci U S A. 1999 Mar 2. 96(5):2110-5. PubMed Journal
Articles Citing 896 pcDNA3 T7 Akt1
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The endogenous inhibitor of Akt, CTMP, is critical to ischemia-induced neuronal death. Miyawaki T, Ofengeim D, Noh KM, Latuszek-Barrantes A, Hemmings BA, Follenzi A, Zukin RS. Nat Neurosci. 2009 May;12(5):618-26. doi: 10.1038/nn.2299. Epub 2009 Apr 6. PubMed |
Molecular targeting of Akt by thymoquinone promotes G(1) arrest through translation inhibition of cyclin D1 and induces apoptosis in breast cancer cells. Rajput S, Kumar BN, Dey KK, Pal I, Parekh A, Mandal M. Life Sci. 2013 Nov 13;93(21):783-90. doi: 10.1016/j.lfs.2013.09.009. Epub 2013 Sep 15. PubMed |
Phospholipase D2 mediates survival signaling through direct regulation of Akt in glioblastoma cells. Bruntz RC, Taylor HE, Lindsley CW, Brown HA. J Biol Chem. 2014 Jan 10;289(2):600-16. doi: 10.1074/jbc.M113.532978. Epub 2013 Nov 20. PubMed |
Overcoming Akt Induced Therapeutic Resistance in Breast Cancer through siRNA and Thymoquinone Encapsulated Multilamellar Gold Niosomes. Rajput S, Puvvada N, Kumar BN, Sarkar S, Konar S, Bharti R, Dey G, Mazumdar A, Pathak A, Fisher PB, Mandal M. Mol Pharm. 2015 Dec 7;12(12):4214-25. doi: 10.1021/acs.molpharmaceut.5b00692. Epub 2015 Nov 10. PubMed |
Chronic exposure to hexachlorobenzene results in down-regulation of connexin43 in the breast. Delisle A, Ferraris E, Plante I. Environ Res. 2015 Nov;143(Pt A):229-40. doi: 10.1016/j.envres.2015.10.020. Epub 2015 Oct 28. PubMed |
Extensive nuclear sphere generation in the human Alzheimer's brain. Kolbe K, Bukhari H, Loosse C, Leonhardt G, Glotzbach A, Pawlas M, Hess K, Theiss C, Muller T. Neurobiol Aging. 2016 Dec;48:103-113. doi: 10.1016/j.neurobiolaging.2016.08.016. Epub 2016 Aug 26. PubMed |
AKT/mTOR signaling pathway is involved in salvianolic acid B-induced autophagy and apoptosis in hepatocellular carcinoma cells. Gong L, Di C, Xia X, Wang J, Chen G, Shi J, Chen P, Xu H, Zhang W. Int J Oncol. 2016 Dec;49(6):2538-2548. doi: 10.3892/ijo.2016.3748. Epub 2016 Oct 24. PubMed |
MK-2206, an allosteric inhibitor of AKT, stimulates LDLR expression and LDL uptake: A potential hypocholesterolemic agent. Bjune K, Sundvold H, Leren TP, Naderi S. Atherosclerosis. 2018 Sep;276:28-38. doi: 10.1016/j.atherosclerosis.2018.07.009. Epub 2018 Jul 7. PubMed |
TCTP protein degradation by targeting mTORC1 and signaling through S6K, Akt, and Plk1 sensitizes lung cancer cells to DNA-damaging drugs. Jeong M, Jeong MH, Kim JE, Cho S, Lee KJ, Park S, Sohn J, Park YG. Sci Rep. 2021 Oct 21;11(1):20812. doi: 10.1038/s41598-021-00247-0. PubMed |
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