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pCsy_complex Citations (6)

Originally described in: Structure Reveals Mechanisms of Viral Suppressors that Intercept a CRISPR RNA-Guided Surveillance Complex.
Chowdhury S, Carter J, Rollins MF, Golden SM, Jackson RN, Hoffmann C, Nosaka L, Bondy-Denomy J, Maxwell KL, Davidson AR, Fischer ER, Lander GC, Wiedenheft B Cell. 2017 Mar 23;169(1):47-57.e11. doi: 10.1016/j.cell.2017.03.012. PubMed Journal

Articles Citing pCsy_complex

Articles
Cas1 and the Csy complex are opposing regulators of Cas2/3 nuclease activity. Rollins MF, Chowdhury S, Carter J, Golden SM, Wilkinson RA, Bondy-Denomy J, Lander GC, Wiedenheft B. Proc Natl Acad Sci U S A. 2017 Apr 24. pii: 201616395. doi: 10.1073/pnas.1616395114. PubMed

Associated Plasmids
Inhibition mechanisms of AcrF9, AcrF8, and AcrF6 against type I-F CRISPR-Cas complex revealed by cryo-EM. Zhang K, Wang S, Li S, Zhu Y, Pintilie GD, Mou TC, Schmid MF, Huang Z, Chiu W. Proc Natl Acad Sci U S A. 2020 Mar 31;117(13):7176-7182. doi: 10.1073/pnas.1922638117. Epub 2020 Mar 13. PubMed
Repurposing type I-F CRISPR-Cas system as a transcriptional activation tool in human cells. Chen Y, Liu J, Zhi S, Zheng Q, Ma W, Huang J, Liu Y, Liu D, Liang P, Songyang Z. Nat Commun. 2020 Jun 19;11(1):3136. doi: 10.1038/s41467-020-16880-8. PubMed

Associated Plasmids
Structural basis for inhibition of the type I-F CRISPR-Cas surveillance complex by AcrIF4, AcrIF7 and AcrIF14. Gabel C, Li Z, Zhang H, Chang L. Nucleic Acids Res. 2021 Jan 11;49(1):584-594. doi: 10.1093/nar/gkaa1199. PubMed
Anti-CRISPR proteins function through thermodynamic tuning and allosteric regulation of CRISPR RNA-guided surveillance complex. Patterson A, White A, Waymire E, Fleck S, Golden S, Wilkinson RA, Wiedenheft B, Bothner B. Nucleic Acids Res. 2022 Oct 28;50(19):11243-11254. doi: 10.1093/nar/gkac841. PubMed
Molecular basis of dual anti-CRISPR and auto-regulatory functions of AcrIF24. Kim GE, Lee SY, Birkholz N, Kamata K, Jeong JH, Kim YG, Fineran PC, Park HH. Nucleic Acids Res. 2022 Oct 28;50(19):11344-11358. doi: 10.1093/nar/gkac880. PubMed

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