PGC-1 alpha promoter 2kb luciferase Citations (27)

Originally described in: An autoregulatory loop controls peroxisome proliferator-activated receptor gamma coactivator 1alpha expression in muscle.
Handschin C, Rhee J, Lin J, Tarr PT, Spiegelman BM Proc Natl Acad Sci U S A. 2003 Jun 10. 100(12):7111-6. PubMed Journal

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Articles Citing PGC-1 alpha promoter 2kb luciferase

Articles
p38 Mitogen-activated protein kinase mediates free fatty acid-induced gluconeogenesis in hepatocytes. Collins QF, Xiong Y, Lupo EG, Liu HY, Cao W. J Biol Chem. 2006 Aug 25. 281(34):24336-44. PubMed
PGC-1{alpha} and PGC-1{beta} regulate mitochondrial density in neurons. Wareski P, Vaarmann A, Choubey V, Safiulina D, Liiv J, Kuum M, Kaasik A. J Biol Chem. 2009 Aug 7. 284(32):21379-85. PubMed
Pyrroloquinoline quinone stimulates mitochondrial biogenesis through cAMP response element-binding protein phosphorylation and increased PGC-1alpha expression. Chowanadisai W, Bauerly KA, Tchaparian E, Wong A, Cortopassi GA, Rucker RB. J Biol Chem. 2010 Jan 1. 285(1):142-52. PubMed
MAPK phosphatase-1 facilitates the loss of oxidative myofibers associated with obesity in mice. Roth RJ, Le AM, Zhang L, Kahn M, Samuel VT, Shulman GI, Bennett AM. J Clin Invest. 2009 Dec;119(12):3817-29. doi: 10.1172/JCI39054. Epub 2009 Nov 16. PubMed
Nitric oxide and AMPK cooperatively regulate PGC-1 in skeletal muscle cells. Lira VA, Brown DL, Lira AK, Kavazis AN, Soltow QA, Zeanah EH, Criswell DS. J Physiol. 2010 Sep 15. 588(Pt 18):3551-66. PubMed
Different effects of oleate vs. palmitate on mitochondrial function, apoptosis, and insulin signaling in L6 skeletal muscle cells: role of oxidative stress. Yuzefovych L, Wilson G, Rachek L. Am J Physiol Endocrinol Metab. 2010 Dec;299(6):E1096-105. doi: 10.1152/ajpendo.00238.2010. Epub 2010 Sep 28. PubMed
Knockdown of MMP-7 inhibits cell proliferation and enhances sensitivity to 5-Fluorouracil and X-ray irradiation in colon cancer cells. Zhang W, Li Y, Yang L, Zhou B, Chen KL, Meng WJ, Liu Y, Hu JK, Sun XF, Zhou ZG. Clin Exp Med. 2014 Feb;14(1):99-106. doi: 10.1007/s10238-012-0212-7. Epub 2012 Oct 20. PubMed
Inhibition of AMPK and Krebs cycle gene expression drives metabolic remodeling of Pten-deficient preneoplastic thyroid cells. Antico Arciuch VG, Russo MA, Kang KS, Di Cristofano A. Cancer Res. 2013 Sep 1;73(17):5459-72. doi: 10.1158/0008-5472.CAN-13-1429. Epub 2013 Jun 24. PubMed
Upregulation of PGC-1alpha expression by Alzheimer's disease-associated pathway: presenilin 1/amyloid precursor protein (APP)/intracellular domain of APP. Robinson A, Grosgen S, Mett J, Zimmer VC, Haupenthal VJ, Hundsdorfer B, Stahlmann CP, Slobodskoy Y, Muller UC, Hartmann T, Stein R, Grimm MO. Aging Cell. 2014 Apr;13(2):263-72. doi: 10.1111/acel.12183. Epub 2013 Dec 17. PubMed
Metformin induces PGC-1alpha expression and selectively affects hepatic PGC-1alpha functions. Aatsinki SM, Buler M, Salomaki H, Koulu M, Pavek P, Hakkola J. Br J Pharmacol. 2014 May;171(9):2351-63. doi: 10.1111/bph.12585. PubMed
Ethanol suppresses PGC-1alpha expression by interfering with the cAMP-CREB pathway in neuronal cells. Liu Z, Liu Y, Gao R, Li H, Dunn T, Wu P, Smith RG, Sarkar PS, Fang X. PLoS One. 2014 Aug 6;9(8):e104247. doi: 10.1371/journal.pone.0104247. eCollection 2014. PubMed
Nuclear Perilipin 5 integrates lipid droplet lipolysis with PGC-1alpha/SIRT1-dependent transcriptional regulation of mitochondrial function. Gallardo-Montejano VI, Saxena G, Kusminski CM, Yang C, McAfee JL, Hahner L, Hoch K, Dubinsky W, Narkar VA, Bickel PE. Nat Commun. 2016 Aug 24;7:12723. doi: 10.1038/ncomms12723. PubMed
IGF-II-mediated downregulation of peroxisome proliferator-activated receptor-gamma coactivator-1alpha in myoblast cells involves PI3K/Akt/FoxO1 signaling pathway. Mu X, Qi W, Liu Y, Zhou J, Li Y, Rong X, Lu L. Mol Cell Biochem. 2017 Aug;432(1-2):199-208. doi: 10.1007/s11010-017-3010-4. Epub 2017 Apr 3. PubMed
Gastrodia elata alleviates mutant huntingtin aggregation through mitochondrial function and biogenesis mediation. Huang CL, Wang KC, Yang YC, Chiou CT, Tan CH, Lin YL, Huang NK. Phytomedicine. 2018 Jan 15;39:75-84. doi: 10.1016/j.phymed.2017.12.017. Epub 2017 Dec 18. PubMed
Decreased mitochondrial respiration in aneurysmal aortas of Fibulin-4 mutant mice is linked to PGC1A regulation. van der Pluijm I, Burger J, van Heijningen PM, IJpma A, van Vliet N, Milanese C, Schoonderwoerd K, Sluiter W, Ringuette LJ, Dekkers DHW, Que I, Kaijzel EL, Te Riet L, MacFarlane EG, Das D, van der Linden R, Vermeij M, Demmers JA, Mastroberardino PG, Davis EC, Yanagisawa H, Dietz HC, Kanaar R, Essers J. Cardiovasc Res. 2018 Nov 1;114(13):1776-1793. doi: 10.1093/cvr/cvy150. PubMed
Neonatal vitamin A injection promotes cattle muscle growth and increases oxidative muscle fibers. Wang B, Nie W, Fu X, de Avila JM, Ma Y, Zhu MJ, Maquivar M, Parish SM, Busboom JR, Nelson ML, Du M. J Anim Sci Biotechnol. 2018 Nov 15;9:82. doi: 10.1186/s40104-018-0296-3. eCollection 2018. PubMed
IRX5 regulates adipocyte amyloid precursor protein and mitochondrial respiration in obesity. Bjune JI, Haugen C, Gudbrandsen O, Nordbo OP, Nielsen HJ, Vage V, Njolstad PR, Sagen JV, Dankel SN, Mellgren G. Int J Obes (Lond). 2018 Dec 11. pii: 10.1038/s41366-018-0275-y. doi: 10.1038/s41366-018-0275-y. PubMed
The Therapeutic Implications of Tea Polyphenols Against Dopamine (DA) Neuron Degeneration in Parkinson's Disease (PD). Zhou ZD, Xie SP, Saw WT, Ho PGH, Wang H, Lei Z, Yi Z, Tan EK. Cells. 2019 Aug 16;8(8). pii: cells8080911. doi: 10.3390/cells8080911. PubMed
NOX4 modulates macrophage phenotype and mitochondrial biogenesis in asbestosis. He C, Larson-Casey JL, Davis D, Hanumanthu VS, Longhini ALF, Thannickal VJ, Gu L, Carter AB. JCI Insight. 2019 Aug 22;4(16). pii: 126551. doi: 10.1172/jci.insight.126551. PubMed
Indoprofen prevents muscle wasting in aged mice through activation of PDK1/AKT pathway. Kim H, Cho SC, Jeong HJ, Lee HY, Jeong MH, Pyun JH, Ryu D, Kim M, Lee YS, Kim MS, Park SC, Lee YI, Kang JS. J Cachexia Sarcopenia Muscle. 2020 Aug;11(4):1070-1088. doi: 10.1002/jcsm.12558. Epub 2020 Feb 25. PubMed
Role of zinc transporter ZIP12 in susceptibility-weighted brain magnetic resonance imaging (MRI) phenotypes and mitochondrial function. Strong MD, Hart MD, Tang TZ, Ojo BA, Wu L, Nacke MR, Agidew WT, Hwang HJ, Hoyt PR, Bettaieb A, Clarke SL, Smith BJ, Stoecker BJ, Lucas EA, Lin D, Chowanadisai W. FASEB J. 2020 Sep;34(9):10702-12725. doi: 10.1096/fj.202000772R. Epub 2020 Jul 27. PubMed
Embryonic exposure to hyper glucocorticoids suppresses brown fat development and thermogenesis via REDD1. Chen YT, Hu Y, Yang QY, Liu XD, Son JS, de Avila JM, Zhu MJ, Du M. Sci Bull (Beijing). 2021 Mar 15;66(5):478-489. doi: 10.1016/j.scib.2020.10.015. Epub 2020 Oct 28. PubMed
Post-translational regulation of PGC-1alpha modulates fibrotic repair. Larson-Casey JL, Gu L, Davis D, Cai GQ, Ding Q, He C, Carter AB. FASEB J. 2021 Jun;35(6):e21675. doi: 10.1096/fj.202100339R. PubMed
Defective Mitochondrial Quality Control during Dengue Infection Contributes to Disease Pathogenesis. Singh B, Avula K, Sufi SA, Parwin N, Das S, Alam MF, Samantaray S, Bankapalli L, Rani A, Poornima K, Prusty B, Mallick TP, Shaw SK, Dodia H, Kabi S, Pagad TT, Mohanty S, Syed GH. J Virol. 2022 Oct 26;96(20):e0082822. doi: 10.1128/jvi.00828-22. Epub 2022 Oct 5. PubMed
Cholic and deoxycholic acids induce mitochondrial dysfunction, impaired biogenesis and autophagic flux in skeletal muscle cells. Abrigo J, Olguin H, Tacchi F, Orozco-Aguilar J, Valero-Breton M, Soto J, Castro-Sepulveda M, Elorza AA, Simon F, Cabello-Verrugio C. Biol Res. 2023 Jun 8;56(1):30. doi: 10.1186/s40659-023-00436-3. PubMed
Inonotus obliquus upregulates muscle regeneration and augments function through muscle oxidative metabolism. You CL, Lee SJ, Lee J, Vuong TA, Lee HY, Jeong SY, Alishir A, Walker AS, Bae GU, Kim KH, Kang JS. Int J Biol Sci. 2023 Sep 11;19(15):4898-4914. doi: 10.7150/ijbs.84970. eCollection 2023. PubMed
Obesity-induced PARIS (ZNF746) accumulation in adipose progenitor cells leads to attenuated mitochondrial biogenesis and impaired adipogenesis. Hachiya K, Deguchi Y, Hirata T, Arikawa T, Fukai H, Esashi T, Nagasawa K, Mizunoe Y, Nozaki Y, Kobayashi M, Higami Y. Sci Rep. 2023 Dec 27;13(1):22990. doi: 10.1038/s41598-023-49996-0. PubMed

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