3541 pMIG Bcl-XL Citations (9)
Originally described in: BCL-2, BCL-X(L) sequester BH3 domain-only molecules preventing BAX- and BAK-mediated mitochondrial apoptosis.Cheng EH, Wei MC, Weiler S, Flavell RA, Mak TW, Lindsten T, Korsmeyer SJ Mol Cell 2001 Sep;8(3):705-11. PubMed Journal
Articles Citing 3541 pMIG Bcl-XL
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Chemotherapy overcomes TRAIL-R4-mediated TRAIL resistance at the DISC level. Morizot A, Merino D, Lalaoui N, Jacquemin G, Granci V, Iessi E, Lanneau D, Bouyer F, Solary E, Chauffert B, Saas P, Garrido C, Micheau O. Cell Death Differ. 2011 Apr;18(4):700-11. doi: 10.1038/cdd.2010.144. Epub 2010 Nov 12. PubMed |
Matrix rigidity regulates a switch between TGF-beta1-induced apoptosis and epithelial-mesenchymal transition. Leight JL, Wozniak MA, Chen S, Lynch ML, Chen CS. Mol Biol Cell. 2012 Mar;23(5):781-91. doi: 10.1091/mbc.E11-06-0537. Epub 2012 Jan 11. PubMed |
dsRNA induces apoptosis through an atypical death complex associating TLR3 to caspase-8. Estornes Y, Toscano F, Virard F, Jacquemin G, Pierrot A, Vanbervliet B, Bonnin M, Lalaoui N, Mercier-Gouy P, Pacheco Y, Salaun B, Renno T, Micheau O, Lebecque S. Cell Death Differ. 2012 Sep;19(9):1482-94. doi: 10.1038/cdd.2012.22. Epub 2012 Mar 16. PubMed |
Bcl11a is essential for lymphoid development and negatively regulates p53. Yu Y, Wang J, Khaled W, Burke S, Li P, Chen X, Yang W, Jenkins NA, Copeland NG, Zhang S, Liu P. J Exp Med. 2012 Dec 17;209(13):2467-83. doi: 10.1084/jem.20121846. Epub 2012 Dec 10. PubMed |
MLL2, Not MLL1, Plays a Major Role in Sustaining MLL-Rearranged Acute Myeloid Leukemia. Chen Y, Anastassiadis K, Kranz A, Stewart AF, Arndt K, Waskow C, Yokoyama A, Jones K, Neff T, Lee Y, Ernst P. Cancer Cell. 2017 Jun 12;31(6):755-770.e6. doi: 10.1016/j.ccell.2017.05.002. PubMed |
Cytoplasmic p53 couples oncogene-driven glucose metabolism to apoptosis and is a therapeutic target in glioblastoma. Mai WX, Gosa L, Daniels VW, Ta L, Tsang JE, Higgins B, Gilmore WB, Bayley NA, Harati MD, Lee JT, Yong WH, Kornblum HI, Bensinger SJ, Mischel PS, Rao PN, Clark PM, Cloughesy TF, Letai A, Nathanson DA. Nat Med. 2017 Nov;23(11):1342-1351. doi: 10.1038/nm.4418. Epub 2017 Oct 9. PubMed |
Mechanisms for mTORC1 activation and synergistic induction of apoptosis by ruxolitinib and BH3 mimetics or autophagy inhibitors in JAK2-V617F-expressing leukemic cells including newly established PVTL-2. Ishida S, Akiyama H, Umezawa Y, Okada K, Nogami A, Oshikawa G, Nagao T, Miura O. Oncotarget. 2018 Jun 1;9(42):26834-26851. doi: 10.18632/oncotarget.25515. eCollection 2018 Jun 1. PubMed |
Selective BH3 mimetics synergize with BET inhibition to induce mitochondrial apoptosis in rhabdomyosarcoma cells. Erdogdu U, Dolgikh N, Laszig S, Sarchen V, Meister MT, Wanior M, Knapp S, Boedicker C. Neoplasia. 2022 Feb;24(2):109-119. doi: 10.1016/j.neo.2021.11.012. Epub 2021 Dec 24. PubMed |
Early Alzheimer's disease pathology in human cortex is associated with a transient phase of distinct cell states. Gazestani V, Kamath T, Nadaf NM, Burris SJ, Rooney B, Junkkari A, Vanderburg C, Rauramaa T, Therrien M, Tegtmeyer M, Herukka SK, Abdulraouf A, Marsh S, Malm T, Hiltunen M, Nehme R, Stevens B, Leinonen V, Macosko EZ. bioRxiv. 2023 Jun 5:2023.06.03.543569. doi: 10.1101/2023.06.03.543569. Preprint. PubMed |
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