TLCV2 Citations (47)
Originally described in: Pan-Cancer Analyses Reveal Genomic Features of FOXM1 Overexpression in Cancer.Barger CJ, Branick C, Chee L, Karpf AR Cancers (Basel). 2019 Feb 21;11(2). pii: cancers11020251. doi: 10.3390/cancers11020251. PubMed Journal
Articles Citing TLCV2
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| Characterization of a Merkel Cell Polyomavirus-Positive Merkel Cell Carcinoma Cell Line CVG-1. Velasquez C, Amako Y, Harold A, Toptan T, Chang Y, Shuda M. Front Microbiol. 2018 Apr 11;9:713. doi: 10.3389/fmicb.2018.00713. eCollection 2018. PubMed |
| Functional Interrogation of Primary Human T Cells via CRISPR Genetic Editing. Chen X, Kozhaya L, Tastan C, Placek L, Dogan M, Horne M, Abblett R, Karhan E, Vaeth M, Feske S, Unutmaz D. J Immunol. 2018 Sep 1;201(5):1586-1598. doi: 10.4049/jimmunol.1701616. Epub 2018 Jul 18. PubMed |
| Mutations in multiple components of the nuclear pore complex cause nephrotic syndrome. Braun DA, Lovric S, Schapiro D, Schneider R, Marquez J, Asif M, Hussain MS, Daga A, Widmeier E, Rao J, Ashraf S, Tan W, Lusk CP, Kolb A, Jobst-Schwan T, Schmidt JM, Hoogstraten CA, Eddy K, Kitzler TM, Shril S, Moawia A, Schrage K, Khayyat AIA, Lawson JA, Gee HY, Warejko JK, Hermle T, Majmundar AJ, Hugo H, Budde B, Motameny S, Altmuller J, Noegel AA, Fathy HM, Gale DP, Waseem SS, Khan A, Kerecuk L, Hashmi S, Mohebbi N, Ettenger R, Serdaroglu E, Alhasan KA, Hashem M, Goncalves S, Ariceta G, Ubetagoyena M, Antonin W, Baig SM, Alkuraya FS, Shen Q, Xu H, Antignac C, Lifton RP, Mane S, Nurnberg P, Khokha MK, Hildebrandt F. J Clin Invest. 2018 Oct 1;128(10):4313-4328. doi: 10.1172/JCI98688. Epub 2018 Sep 4. PubMed |
| Double-strand breakage in the extrachromosomal double minutes triggers their aggregation in the nucleus, micronucleation, and morphological transformation. Oobatake Y, Shimizu N. Genes Chromosomes Cancer. 2020 Mar;59(3):133-143. doi: 10.1002/gcc.22810. Epub 2019 Oct 4. PubMed |
Inducible Exoc7/Exo70 knockout reveals a critical role of the exocyst in insulin-regulated GLUT4 exocytosis.
Wang S, Crisman L, Miller J, Datta I, Gulbranson DR, Tian Y, Yin Q, Yu H, Shen J.
J Biol Chem. 2019 Dec 27;294(52):19988-19996. doi: 10.1074/jbc.RA119.010821. Epub 2019 Nov 18.
PubMed
Associated Plasmids |
| A potent KRAS macromolecule degrader specifically targeting tumours with mutant KRAS. Bery N, Miller A, Rabbitts T. Nat Commun. 2020 Jun 26;11(1):3233. doi: 10.1038/s41467-020-17022-w. PubMed |
| Intrinsic ATR signaling shapes DNA end resection and suppresses toxic DNA-PKcs signaling. Dibitetto D, Sims JR, Ascencao CFR, Feng K, Kim D, Oberly S, Freire R, Smolka MB. NAR Cancer. 2020 Jun;2(2):zcaa006. doi: 10.1093/narcan/zcaa006. Epub 2020 May 1. PubMed |
| Growth of pancreatic cancers with hemizygous chromosomal 17p loss of MYBBP1A can be preferentially targeted by PARP inhibitors. Hsieh A, Pitarresi JR, Lerner J, Donahue G, Hsiehchen D, Rustgi AK, Zaret K. Sci Adv. 2020 Dec 4;6(49). pii: 6/49/eabc4517. doi: 10.1126/sciadv.abc4517. Print 2020 Dec. PubMed |
| Tipping the immunostimulatory and inhibitory DAMP balance to harness immunogenic cell death. Hayashi K, Nikolos F, Lee YC, Jain A, Tsouko E, Gao H, Kasabyan A, Leung HE, Osipov A, Jung SY, Kurtova AV, Chan KS. Nat Commun. 2020 Dec 7;11(1):6299. doi: 10.1038/s41467-020-19970-9. PubMed |
| REST Protects Dopaminergic Neurons from Mitochondrial and alpha-Synuclein Oligomer Pathology in an Alpha Synuclein Overexpressing BAC-Transgenic Mouse Model. Ryan BJ, Bengoa-Vergniory N, Williamson M, Kirkiz E, Roberts R, Corda G, Sloan M, Saqlain S, Cherubini M, Poppinga J, Bogtofte H, Cioroch M, Hester S, Wade-Martins R. J Neurosci. 2021 Apr 21;41(16):3731-3746. doi: 10.1523/JNEUROSCI.1478-20.2021. Epub 2021 Feb 9. PubMed |
| Derivation of stem cell line UMi028-A-2 containing a CRISPR/Cas9 induced Alzheimer's disease risk variant p.S1038C in the TTC3 gene. Laverde-Paz MJ, Nuytemans K, Wang L, Vance JM, Pericak-Vance MA, Dykxhoorn DM, Cukier HN. Stem Cell Res. 2021 Apr;52:102258. doi: 10.1016/j.scr.2021.102258. Epub 2021 Feb 18. PubMed |
| The bone microenvironment invigorates metastatic seeds for further dissemination. Zhang W, Bado IL, Hu J, Wan YW, Wu L, Wang H, Gao Y, Jeong HH, Xu Z, Hao X, Lege BM, Al-Ouran R, Li L, Li J, Yu L, Singh S, Lo HC, Niu M, Liu J, Jiang W, Li Y, Wong STC, Cheng C, Liu Z, Zhang XH. Cell. 2021 Apr 29;184(9):2471-2486.e20. doi: 10.1016/j.cell.2021.03.011. Epub 2021 Apr 19. PubMed |
| HOXA13 in etiology and oncogenic potential of Barrett's esophagus. Janmaat VT, Nesteruk K, Spaander MCW, Verhaar AP, Yu B, Silva RA, Phillips WA, Magierowski M, van de Winkel A, Stadler HS, Sandoval-Guzman T, van der Laan LJW, Kuipers EJ, Smits R, Bruno MJ, Fuhler GM, Clemons NJ, Peppelenbosch MP. Nat Commun. 2021 Jun 7;12(1):3354. doi: 10.1038/s41467-021-23641-8. PubMed |
| An androgen receptor switch underlies lineage infidelity in treatment-resistant prostate cancer. Davies A, Nouruzi S, Ganguli D, Namekawa T, Thaper D, Linder S, Karaoglanoglu F, Omur ME, Kim S, Kobelev M, Kumar S, Sivak O, Bostock C, Bishop J, Hoogstraat M, Talal A, Stelloo S, van der Poel H, Bergman AM, Ahmed M, Fazli L, Huang H, Tilley W, Goodrich D, Feng FY, Gleave M, He HH, Hach F, Zwart W, Beltran H, Selth L, Zoubeidi A. Nat Cell Biol. 2021 Sep;23(9):1023-1034. doi: 10.1038/s41556-021-00743-5. Epub 2021 Sep 6. PubMed |
| Sox2 Is an Oncogenic Driver of Small-Cell Lung Cancer and Promotes the Classic Neuroendocrine Subtype. Voigt E, Wallenburg M, Wollenzien H, Thompson E, Kumar K, Feiner J, McNally M, Friesen H, Mukherjee M, Afeworki Y, Kareta MS. Mol Cancer Res. 2021 Dec;19(12):2015-2025. doi: 10.1158/1541-7786.MCR-20-1006. Epub 2021 Sep 30. PubMed |
| Sub-centrosomal mapping identifies augmin-gammaTuRC as part of a centriole-stabilizing scaffold. Schweizer N, Haren L, Dutto I, Viais R, Lacasa C, Merdes A, Luders J. Nat Commun. 2021 Oct 15;12(1):6042. doi: 10.1038/s41467-021-26252-5. PubMed |
| CRISPR-based RNA-binding protein mapping in live cells. Chen B, Shi H, Zhang J, Zhou C, Han M, Jiang W, Lai Y, Tu X, Li H. Biochem Biophys Res Commun. 2021 Oct 29;583:79-85. doi: 10.1016/j.bbrc.2021.10.059. PubMed |
| Epigenetic modifier balances Mapk and Wnt signalling in differentiation of goblet and Paneth cells. Grinat J, Kosel F, Goveas N, Kranz A, Alexopoulou D, Rajewsky K, Sigal M, Stewart AF, Heuberger J. Life Sci Alliance. 2022 Jan 21;5(4). pii: 5/4/e202101187. doi: 10.26508/lsa.202101187. Print 2022 Apr. PubMed |
scDART-seq reveals distinct m(6)A signatures and mRNA methylation heterogeneity in single cells.
Tegowski M, Flamand MN, Meyer KD.
Mol Cell. 2022 Feb 17;82(4):868-878.e10. doi: 10.1016/j.molcel.2021.12.038. Epub 2022 Jan 25.
PubMed
Associated Plasmids |
| ATG7-mediated autophagy facilitates embryonic stem cell exit from naive pluripotency and marks commitment to differentiation. Zhou J, He H, Zhang JJ, Liu X, Yao W, Li C, Xu T, Yin SY, Wu DY, Dou CL, Li Q, Xiang J, Xiong WJ, Wang LY, Tang JM, Xue Z, Zhang X, Miao YL. Autophagy. 2022 Apr 10:1-23. doi: 10.1080/15548627.2022.2055285. PubMed |
| NUP133 Controls Nuclear Pore Assembly, Transcriptome Composition, and Cytoskeleton Regulation in Podocytes. Rogg M, Maier JI, Ehle M, Sammarco A, Schilling O, Werner M, Schell C. Cells. 2022 Apr 7;11(8). pii: cells11081259. doi: 10.3390/cells11081259. PubMed |
| ASCL1 activates neuronal stem cell-like lineage programming through remodeling of the chromatin landscape in prostate cancer. Nouruzi S, Ganguli D, Tabrizian N, Kobelev M, Sivak O, Namekawa T, Thaper D, Baca SC, Freedman ML, Aguda A, Davies A, Zoubeidi A. Nat Commun. 2022 Apr 27;13(1):2282. doi: 10.1038/s41467-022-29963-5. PubMed |
| PI3K drives the de novo synthesis of coenzyme A from vitamin B5. Dibble CC, Barritt SA, Perry GE, Lien EC, Geck RC, DuBois-Coyne SE, Bartee D, Zengeya TT, Cohen EB, Yuan M, Hopkins BD, Meier JL, Clohessy JG, Asara JM, Cantley LC, Toker A. Nature. 2022 Aug;608(7921):192-198. doi: 10.1038/s41586-022-04984-8. Epub 2022 Jul 27. PubMed |
| Protective role of Cav-1 in pneumolysin-induced endothelial barrier dysfunction. Batori RK, Chen F, Bordan Z, Haigh S, Su Y, Verin AD, Barman SA, Stepp DW, Chakraborty T, Lucas R, Fulton DJR. Front Immunol. 2022 Jul 27;13:945656. doi: 10.3389/fimmu.2022.945656. eCollection 2022. PubMed |
| Escape from NK cell tumor surveillance by NGFR-induced lipid remodeling in melanoma. Lehmann J, Caduff N, Krzywinska E, Stierli S, Salas-Bastos A, Loos B, Levesque MP, Dummer R, Stockmann C, Munz C, Diener J, Sommer L. Sci Adv. 2023 Jan 13;9(2):eadc8825. doi: 10.1126/sciadv.adc8825. Epub 2023 Jan 13. PubMed |
| Soluble cyclase-mediated nuclear cAMP synthesis is sufficient for cell proliferation. Pizzoni A, Zhang X, Naim N, Altschuler DL. Proc Natl Acad Sci U S A. 2023 Jan 24;120(4):e2208749120. doi: 10.1073/pnas.2208749120. Epub 2023 Jan 19. PubMed |
| A genome-wide CRISPR functional survey of the human phagocytosis molecular machinery. Essletzbichler P, Sedlyarov V, Frommelt F, Soulat D, Heinz LX, Stefanovic A, Neumayer B, Superti-Furga G. Life Sci Alliance. 2023 Feb 1;6(4):e202201715. doi: 10.26508/lsa.202201715. Print 2023 Apr. PubMed |
| The APE2 nuclease is essential for DNA double-strand break repair by microhomology-mediated end joining. Fleury H, MacEachern MK, Stiefel CM, Anand R, Sempeck C, Nebenfuehr B, Maurer-Alcala K, Ball K, Proctor B 3rd, Belan O, Taylor E, Ortega R, Dodd B, Weatherly L, Dansoko D, Leung JW, Boulton SJ, Arnoult N. Mol Cell. 2023 May 4;83(9):1429-1445.e8. doi: 10.1016/j.molcel.2023.03.017. Epub 2023 Apr 11. PubMed |
| IGFBP7 Fuels the Glycolytic Metabolism in B-Cell Precursor Acute Lymphoblastic Leukemia by Sustaining Activation of the IGF1R-Akt-GLUT1 Axis. Artico LL, Ruas JS, Teixeira Junior JR, Migita NA, Seguchi G, Shi X, Brandalise SR, Castilho RF, Yunes JA. Int J Mol Sci. 2023 Jun 2;24(11):9679. doi: 10.3390/ijms24119679. PubMed |
| Intracellular pH dynamics regulates intestinal stem cell lineage specification. Liu Y, Reyes E, Castillo-Azofeifa D, Klein OD, Nystul T, Barber DL. Nat Commun. 2023 Jun 23;14(1):3745. doi: 10.1038/s41467-023-39312-9. PubMed |
| Calcium dysregulation combined with mitochondrial failure and electrophysiological maturity converge in Parkinson's iPSC-dopamine neurons. Beccano-Kelly DA, Cherubini M, Mousba Y, Cramb KML, Giussani S, Caiazza MC, Rai P, Vingill S, Bengoa-Vergniory N, Ng B, Corda G, Banerjee A, Vowles J, Cowley S, Wade-Martins R. iScience. 2023 Jun 7;26(7):107044. doi: 10.1016/j.isci.2023.107044. eCollection 2023 Jul 21. PubMed |
| HSV-1 exploits host heterochromatin for nuclear egress. Lewis HC, Kelnhofer-Millevolte LE, Brinkley MR, Arbach HE, Arnold EA, Sanders S, Bosse JB, Ramachandran S, Avgousti DC. J Cell Biol. 2023 Sep 4;222(9):e202304106. doi: 10.1083/jcb.202304106. Epub 2023 Jul 26. PubMed |
| Efficient genome editing in erythroid cells unveils novel MYB target genes and regulatory functions. Deleuze V, Garcia L, Rouaisnel B, Salma M, Kinoo A, Andrieu-Soler C, Soler E. iScience. 2023 Aug 15;26(9):107641. doi: 10.1016/j.isci.2023.107641. eCollection 2023 Sep 15. PubMed |
| Epigenetic regulation of p63 blocks squamous-to-neuroendocrine transdifferentiation in esophageal development and malignancy. Zhang Y, Karagiannis D, Liu H, Lin M, Fang Y, Jiang M, Chen X, Suresh S, Huang H, She J, Shi F, Yang P, El-Rifai W, Zaika A, Oro AE, Rustgi AK, Wang TC, Lu C, Que J. bioRxiv [Preprint]. 2023 Sep 11:2023.09.09.556982. doi: 10.1101/2023.09.09.556982. PubMed |
| Branched-chain amino acid transaminase 1 regulates glioblastoma cell plasticity and contributes to immunosuppression. Boskovic P, Wilke N, Man KH, Lichter P, Francois L, Radlwimmer B. Neuro Oncol. 2024 Feb 2;26(2):251-265. doi: 10.1093/neuonc/noad190. PubMed |
| In situ visualization of m6A sites in cellular mRNAs. Sheehan CJ, Marayati BF, Bhatia J, Meyer KD. Nucleic Acids Res. 2023 Nov 10;51(20):e101. doi: 10.1093/nar/gkad787. PubMed |
Mitochondrial DNA breaks activate an integrated stress response to reestablish homeostasis.
Fu Y, Sacco O, DeBitetto E, Kanshin E, Ueberheide B, Sfeir A.
Mol Cell. 2023 Oct 8:S1097-2765(23)00753-0. doi: 10.1016/j.molcel.2023.09.026.
PubMed
Associated Plasmids |
A scalable and tunable platform for functional interrogation of peptide hormones in fish.
Moses E, Franek R, Harel I.
eLife. 2023 Oct 24;12:e85960. doi: 10.7554/eLife.85960.
PubMed
Associated Plasmids |
| Wild-type C-Raf gene dosage and dimerization drive prostate cancer metastasis. Ta L, Tsai BL, Deng W, Sha J, Varuzhanyan G, Tran W, Wohlschlegel JA, Carr-Ascher JR, Witte ON. iScience. 2023 Nov 17;26(12):108480. doi: 10.1016/j.isci.2023.108480. eCollection 2023 Dec 15. PubMed |
Programmable protein expression using a genetically encoded m(6)A sensor.
Marayati BF, Thompson MG, Holley CL, Horner SM, Meyer KD.
Nat Biotechnol. 2024 Jan 2. doi: 10.1038/s41587-023-01978-3.
PubMed
Associated Plasmids |
| MAPK phosphatase 1 inhibition of p38alpha within lung myofibroblasts is essential for spontaneous fibrosis resolution. Fortier SM, Walker NM, Penke LR, Baas JD, Shen Q, Speth JM, Huang SK, Zemans RL, Bennett AM, Peters-Golden M. J Clin Invest. 2024 Mar 21;134(10):e172826. doi: 10.1172/JCI172826. PubMed |
| Aberrant non-canonical NF-kappaB signalling reprograms the epigenome landscape to drive oncogenic transcriptomes in multiple myeloma. Ang DA, Carter JM, Deka K, Tan JHL, Zhou J, Chen Q, Chng WJ, Harmston N, Li Y. Nat Commun. 2024 Mar 21;15(1):2513. doi: 10.1038/s41467-024-46728-4. PubMed |
| Protocol for efficient CRISPR-Cas9-mediated fluorescent tag knockin in hard-to-transfect erythroid cell lines. Deleuze V, Soler E, Andrieu-Soler C. STAR Protoc. 2024 Jun 21;5(2):103016. doi: 10.1016/j.xpro.2024.103016. Epub 2024 Apr 17. PubMed |
| CRISPR-Cas9 screening identifies INTS3 as an anti-apoptotic RNA-binding protein and therapeutic target for colorectal cancer. Wang Z, Zhang C, Guo J, Yang Y, Li P, Wang Z, Liu S, Zhang L, Zeng X, Zhai J, Wang X, Zhao Q, Chen Z, Zhu P, He Q. iScience. 2024 Apr 6;27(5):109676. doi: 10.1016/j.isci.2024.109676. eCollection 2024 May 17. PubMed |
| Discovery of SOCS7 as a versatile E3 ligase for protein-based degraders. Cornebois A, Sorbara M, Cristol M, Vigne E, Cordelier P, Desrumeaux K, Bery N. iScience. 2024 Apr 23;27(5):109802. doi: 10.1016/j.isci.2024.109802. eCollection 2024 May 17. PubMed |
| TDP1 mutation causing SCAN1 neurodegenerative syndrome hampers the repair of transcriptional DNA double-strand breaks. Geraud M, Cristini A, Salimbeni S, Bery N, Jouffret V, Russo M, Ajello AC, Fernandez Martinez L, Marinello J, Cordelier P, Trouche D, Favre G, Nicolas E, Capranico G, Sordet O. Cell Rep. 2024 May 28;43(5):114214. doi: 10.1016/j.celrep.2024.114214. Epub 2024 May 17. PubMed |
| PGC-1alpha repression dysregulates lipid metabolism and induces lipid droplet accumulation in retinal pigment epithelium. Zhou S, Taskintuna K, Hum J, Gulati J, Olaya S, Steinman J, Golestaneh N. Cell Death Dis. 2024 Jun 1;15(6):385. doi: 10.1038/s41419-024-06762-y. PubMed |
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