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Stat3 Y705F Flag pRc/CMV Citations (17)

Originally described in: Mapping of Stat3 serine phosphorylation to a single residue (727) and evidence that serine phosphorylation has no influence on DNA binding of Stat1 and Stat3.
Wen Z, Darnell JE Jr Nucleic Acids Res 1997 Jun 1;25(11):2062-7.
PubMed Journal

Articles Citing Stat3 Y705F Flag pRc/CMV

Articles
S100A7 (psoriasin) is induced by the proinflammatory cytokines oncostatin-M and interleukin-6 in human breast cancer. West NR, Watson PH. Oncogene. 2010 Apr 8;29(14):2083-92. doi: 10.1038/onc.2009.488. Epub 2010 Jan 18. PubMed
Gprc5a deletion enhances the transformed phenotype in normal and malignant lung epithelial cells by eliciting persistent Stat3 signaling induced by autocrine leukemia inhibitory factor. Chen Y, Deng J, Fujimoto J, Kadara H, Men T, Lotan D, Lotan R. Cancer Res. 2010 Nov 1;70(21):8917-26. doi: 10.1158/0008-5472.CAN-10-0518. Epub 2010 Oct 19. PubMed
JAK/STAT3 pathway inhibition blocks skeletal muscle wasting downstream of IL-6 and in experimental cancer cachexia. Bonetto A, Aydogdu T, Jin X, Zhang Z, Zhan R, Puzis L, Koniaris LG, Zimmers TA. Am J Physiol Endocrinol Metab. 2012 Aug 1;303(3):E410-21. doi: 10.1152/ajpendo.00039.2012. Epub 2012 Jun 5. PubMed
Targeting mitochondrial STAT3 with the novel phospho-valproic acid (MDC-1112) inhibits pancreatic cancer growth in mice. Mackenzie GG, Huang L, Alston N, Ouyang N, Vrankova K, Mattheolabakis G, Constantinides PP, Rigas B. PLoS One. 2013 May 1;8(5):e61532. doi: 10.1371/journal.pone.0061532. Print 2013. PubMed
Leptin regulation of Hsp60 impacts hypothalamic insulin signaling. Kleinridders A, Lauritzen HP, Ussar S, Christensen JH, Mori MA, Bross P, Kahn CR. J Clin Invest. 2013 Nov;123(11):4667-80. PubMed
Everolimus-induced epithelial to mesenchymal transition in immortalized human renal proximal tubular epithelial cells: key role of heparanase. Masola V, Zaza G, Granata S, Gambaro G, Onisto M, Lupo A. J Transl Med. 2013 Nov 20;11:292. doi: 10.1186/1479-5876-11-292. PubMed
Everolimus-induced human keratinocytes toxicity is mediated by STAT3 inhibition. Yamamoto K, Uda A, Mukai A, Yamashita K, Kume M, Makimoto H, Bito T, Nishigori C, Hirano T, Hirai M. J Exp Clin Cancer Res. 2013 Oct 25;32:83. doi: 10.1186/1756-9966-32-83. PubMed
HPV16 E2-mediated potentiation of NF-kappaB activation induced by TNF-alpha involves parallel activation of STAT3 with a reduction in E2-induced apoptosis. Prabhavathy D, Prabhakar BN, Karunagaran D. Mol Cell Biochem. 2014 Sep;394(1-2):77-90. doi: 10.1007/s11010-014-2083-6. Epub 2014 May 16. PubMed
Phosphoproteomic profiling reveals IL6-mediated paracrine signaling within the Ewing sarcoma family of tumors. Anderson JL, Titz B, Akiyama R, Komisopoulou E, Park A, Tap WD, Graeber TG, Denny CT. Mol Cancer Res. 2014 Dec;12(12):1740-54. doi: 10.1158/1541-7786.MCR-14-0159. Epub 2014 Aug 4. PubMed
IL-6/STAT3 promotes regeneration of airway ciliated cells from basal stem cells. Tadokoro T, Wang Y, Barak LS, Bai Y, Randell SH, Hogan BL. Proc Natl Acad Sci U S A. 2014 Sep 2;111(35):E3641-9. doi: 10.1073/pnas.1409781111. Epub 2014 Aug 18. PubMed
A noncanonical Frizzled2 pathway regulates epithelial-mesenchymal transition and metastasis. Gujral TS, Chan M, Peshkin L, Sorger PK, Kirschner MW, MacBeath G. Cell. 2014 Nov 6;159(4):844-56. doi: 10.1016/j.cell.2014.10.032. PubMed
A new minimally-invasive method for microinjection into the mouse spinal dorsal horn. Kohro Y, Sakaguchi E, Tashima R, Tozaki-Saitoh H, Okano H, Inoue K, Tsuda M. Sci Rep. 2015 Sep 21;5:14306. doi: 10.1038/srep14306. PubMed
MicroRNA 17-5p regulates autophagy in Mycobacterium tuberculosis-infected macrophages by targeting Mcl-1 and STAT3. Kumar R, Sahu SK, Kumar M, Jana K, Gupta P, Gupta UD, Kundu M, Basu J. Cell Microbiol. 2015 Oct 29. doi: 10.1111/cmi.12540. PubMed
Proline-rich tyrosine kinase 2 via enhancing signal transducer and activator of transcription 3-dependent cJun expression mediates retinal neovascularization. Kumar R, Singh NK, Rao GN. Sci Rep. 2016 May 23;6:26480. doi: 10.1038/srep26480. PubMed
STAT3 promotes IFNgamma/TNFalpha-induced muscle wasting in an NF-kappaB-dependent and IL-6-independent manner. Ma JF, Sanchez BJ, Hall DT, Tremblay AK, Di Marco S, Gallouzi IE. EMBO Mol Med. 2017 May;9(5):622-637. doi: 10.15252/emmm.201607052. PubMed
Interleukin-6 promotes a sustained loss of endothelial barrier function via Janus kinase-mediated STAT3 phosphorylation and de novo protein synthesis. Alsaffar H, Martino N, Garrett JP, Adam AP. Am J Physiol Cell Physiol. 2018 Jan 10. doi: 10.1152/ajpcell.00235.2017. PubMed

Associated Plasmids

Kruppel-like factor 4 upregulates matrix metalloproteinase 13 expression in chondrocytes via mRNA stabilization. Takeuchi Y, Tatsuta S, Kito A, Fujikawa J, Itoh S, Itoh Y, Akiyama S, Yamashiro T, Wakisaka S, Abe M. Cell Tissue Res. 2020 Jun 15. pii: 10.1007/s00441-020-03228-3. doi: 10.1007/s00441-020-03228-3. PubMed

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