pTRIP-CMV-GFP-FLAG-cGAS Citations (10)
Originally described in: ESCRT III repairs nuclear envelope ruptures during cell migration to limit DNA damage and cell death.Raab M, Gentili M, de Belly H, Thiam HR, Vargas P, Jimenez AJ, Lautenschlaeger F, Voituriez R, Lennon-Dumenil AM, Manel N, Piel M Science. 2016 Apr 15;352(6283):359-62. doi: 10.1126/science.aad7611. Epub 2016 Mar 24. PubMed Journal
Articles Citing pTRIP-CMV-GFP-FLAG-cGAS
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BAK/BAX macropores facilitate mitochondrial herniation and mtDNA efflux during apoptosis.
McArthur K, Whitehead LW, Heddleston JM, Li L, Padman BS, Oorschot V, Geoghegan ND, Chappaz S, Davidson S, San Chin H, Lane RM, Dramicanin M, Saunders TL, Sugiana C, Lessene R, Osellame LD, Chew TL, Dewson G, Lazarou M, Ramm G, Lessene G, Ryan MT, Rogers KL, van Delft MF, Kile BT.
Science. 2018 Feb 23;359(6378). pii: 359/6378/eaao6047. doi: 10.1126/science.aao6047.
PubMed
Associated Plasmids |
| Poxviruses Evade Cytosolic Sensing through Disruption of an mTORC1-mTORC2 Regulatory Circuit. Meade N, Furey C, Li H, Verma R, Chai Q, Rollins MG, DiGiuseppe S, Naghavi MH, Walsh D. Cell. 2018 Aug 23;174(5):1143-1157.e17. doi: 10.1016/j.cell.2018.06.053. Epub 2018 Aug 2. PubMed |
| Emerin induces nuclear breakage in Xenopus extract and early embryos. Dilsaver MR, Chen P, Thompson TA, Reusser T, Mukherjee RN, Oakey J, Levy DL. Mol Biol Cell. 2018 Oct 17:mbcE18050277. doi: 10.1091/mbc.E18-05-0277. PubMed |
| Chromatin-bound cGAS is an inhibitor of DNA repair and hence accelerates genome destabilization and cell death. Jiang H, Xue X, Panda S, Kawale A, Hooy RM, Liang F, Sohn J, Sung P, Gekara NO. EMBO J. 2019 Oct 4;38(21):e102718. doi: 10.15252/embj.2019102718. Epub 2019 Sep 23. PubMed |
| Heterochromatin-Driven Nuclear Softening Protects the Genome against Mechanical Stress-Induced Damage. Nava MM, Miroshnikova YA, Biggs LC, Whitefield DB, Metge F, Boucas J, Vihinen H, Jokitalo E, Li X, Garcia Arcos JM, Hoffmann B, Merkel R, Niessen CM, Dahl KN, Wickstrom SA. Cell. 2020 May 14;181(4):800-817.e22. doi: 10.1016/j.cell.2020.03.052. Epub 2020 Apr 16. PubMed |
| Expression of the Ebola Virus VP24 Protein Compromises the Integrity of the Nuclear Envelope and Induces a Laminopathy-Like Cellular Phenotype. Vidal S, Sanchez-Aparicio M, Seoane R, El Motiam A, Nelson EV, Bouzaher YH, Baz-Martinez M, Garcia-Dorival I, Gonzalo S, Vazquez E, Vidal A, Munoz-Fontela C, Garcia-Sastre A, Rivas C. mBio. 2021 Aug 31;12(4):e0097221. doi: 10.1128/mBio.00972-21. Epub 2021 Jul 6. PubMed |
| Deficiency in coatomer complex I causes aberrant activation of STING signalling. Steiner A, Hrovat-Schaale K, Prigione I, Yu CH, Laohamonthonkul P, Harapas CR, Low RRJ, De Nardo D, Dagley LF, Mlodzianoski MJ, Rogers KL, Zillinger T, Hartmann G, Gantier MP, Gattorno M, Geyer M, Volpi S, Davidson S, Masters SL. Nat Commun. 2022 Apr 28;13(1):2321. doi: 10.1038/s41467-022-29946-6. PubMed |
| Ambient PM2.5 exposure causes cellular senescence via DNA damage, micronuclei formation, and cGAS activation. Wu T, Xu S, Chen B, Bao L, Ma J, Han W, Xu A, Yu KN, Wu L, Chen S. Nanotoxicology. 2022 Aug-Oct;16(6-8):757-775. doi: 10.1080/17435390.2022.2147460. Epub 2022 Nov 20. PubMed |
MRE11 liberates cGAS from nucleosome sequestration during tumorigenesis.
Cho MG, Kumar RJ, Lin CC, Boyer JA, Shahir JA, Fagan-Solis K, Simpson DA, Fan C, Foster CE, Goddard AM, Lerner LM, Ellington SW, Wang Q, Wang Y, Ho AY, Liu P, Perou CM, Zhang Q, McGinty RK, Purvis JE, Gupta GP.
Nature. 2024 Jan 10. doi: 10.1038/s41586-023-06889-6.
PubMed
Associated Plasmids |
| African swine fever virus early protein pI73R suppresses the type-I IFN promoter activities. Lai DC, Chaudhari J, Vu HLX. Virus Res. 2024 May;343:199342. doi: 10.1016/j.virusres.2024.199342. Epub 2024 Mar 1. PubMed |
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