p4458 FLAG-hPLIC-1 Citations (11)
Originally described in: The hPLIC proteins may provide a link between the ubiquitination machinery and the proteasome.Kleijnen MF, Shih AH, Zhou P, Kumar S, Soccio RE, Kedersha NL, Gill G, Howley PM Mol Cell 2000 Aug;6(2):409-19. PubMed Journal
Articles Citing p4458 FLAG-hPLIC-1
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Ubiquitination, localization, and stability of an anti-apoptotic BCL2-like protein, BCL2L10/BCLb, are regulated by Ubiquilin1. Beverly LJ, Lockwood WW, Shah PP, Erdjument-Bromage H, Varmus H. Proc Natl Acad Sci U S A. 2012 Jan 17;109(3):E119-26. doi: 10.1073/pnas.1119167109. Epub 2012 Jan 10. PubMed |
Association of UBQLN1 mutation with Brown-Vialetto-Van Laere syndrome but not typical ALS. Gonzalez-Perez P, Lu Y, Chian RJ, Sapp PC, Tanzi RE, Bertram L, McKenna-Yasek D, Gao FB, Brown RH Jr. Neurobiol Dis. 2012 Dec;48(3):391-8. doi: 10.1016/j.nbd.2012.06.018. Epub 2012 Jul 3. PubMed |
The TREX1 C-terminal region controls cellular localization through ubiquitination. Orebaugh CD, Fye JM, Harvey S, Hollis T, Wilkinson JC, Perrino FW. J Biol Chem. 2013 Oct 4;288(40):28881-92. doi: 10.1074/jbc.M113.503391. Epub 2013 Aug 26. PubMed |
The ubiquitin ligase HERC3 attenuates NF-kappaB-dependent transcription independently of its enzymatic activity by delivering the RelA subunit for degradation. Hochrainer K, Pejanovic N, Olaseun VA, Zhang S, Iadecola C, Anrather J. Nucleic Acids Res. 2015 Nov 16;43(20):9889-904. doi: 10.1093/nar/gkv1064. Epub 2015 Oct 17. PubMed |
Ubiquilin/Dsk2 promotes inclusion body formation and vacuole (lysosome)-mediated disposal of mutated huntingtin. Chuang KH, Liang F, Higgins R, Wang Y. Mol Biol Cell. 2016 Jul 1;27(13):2025-36. doi: 10.1091/mbc.E16-01-0026. Epub 2016 May 11. PubMed |
The STI and UBA Domains of UBQLN1 are Critical Determinants of Substrate Interaction and Proteostasis. Kurlawala Z, Shah PP, Shah C, Beverly LJ. J Cell Biochem. 2017 Jan 11. doi: 10.1002/jcb.25880. PubMed |
Autophagy and Ubiquitin-Proteasome System Coordinate to Regulate the Protein Quality Control of Neurodegenerative Disease-Associated DCTN1. Wang N, Ma Q, Peng P, Yu Y, Xu S, Wang G, Ying Z, Wang H. Neurotox Res. 2020 Jan;37(1):48-57. doi: 10.1007/s12640-019-00113-y. Epub 2019 Oct 25. PubMed |
Shared and divergent phase separation and aggregation properties of brain-expressed ubiquilins. Gerson JE, Linton H, Xing J, Sutter AB, Kakos FS, Ryou J, Liggans N, Sharkey LM, Safren N, Paulson HL, Ivanova MI. Sci Rep. 2021 Jan 11;11(1):287. doi: 10.1038/s41598-020-78775-4. PubMed |
Disrupting the Balance of Protein Quality Control Protein UBQLN2 Accelerates Tau Proteinopathy. Gerson JE, Sandoval-Pistorius S, Welday JP, Rodriguez A, Gregory JD, Liggans N, Schache K, Li X, Trzeciakiewicz H, Barmada S, Sharkey LM, Paulson HL. J Neurosci. 2022 Mar 2;42(9):1845-1863. doi: 10.1523/JNEUROSCI.1116-21.2021. Epub 2022 Jan 26. PubMed |
RTL8 promotes nuclear localization of UBQLN2 to subnuclear compartments associated with protein quality control. Mohan HM, Trzeciakiewicz H, Pithadia A, Crowley EV, Pacitto R, Safren N, Trotter B, Zhang C, Zhou X, Zhang Y, Basrur V, Paulson HL, Sharkey LM. Cell Mol Life Sci. 2022 Mar 5;79(3):176. doi: 10.1007/s00018-022-04170-z. PubMed |
Ubiquilin-2 regulates pathological alpha-synuclein. Sandoval-Pistorius SS, Gerson JE, Liggans N, Ryou JH, Oak K, Li X, Negron-Rios KY, Fischer S, Barsh H, Crowley EV, Skinner ME, Sharkey LM, Barmada SJ, Paulson HL. Sci Rep. 2023 Jan 6;13(1):293. doi: 10.1038/s41598-022-26899-0. PubMed |
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