p4455 FLAG-hPLIC-2 Citations (12)

Originally described in: The hPLIC proteins may provide a link between the ubiquitination machinery and the proteasome.
Kleijnen MF, Shih AH, Zhou P, Kumar S, Soccio RE, Kedersha NL, Gill G, Howley PM Mol Cell 2000 Aug;6(2):409-19. PubMed Journal

---

Articles Citing p4455 FLAG-hPLIC-2

Articles
Differential recruitment of UBQLN2 to nuclear inclusions in the polyglutamine diseases HD and SCA3. Zeng L, Wang B, Merillat SA, N Minakawa E, Perkins MD, Ramani B, Tallaksen-Greene SJ, Costa MD, Albin RL, Paulson HL. Neurobiol Dis. 2015 Jun 30;82:281-288. doi: 10.1016/j.nbd.2015.06.017. PubMed
Ubiquilin/Dsk2 promotes inclusion body formation and vacuole (lysosome)-mediated disposal of mutated huntingtin. Chuang KH, Liang F, Higgins R, Wang Y. Mol Biol Cell. 2016 Jul 1;27(13):2025-36. doi: 10.1091/mbc.E16-01-0026. Epub 2016 May 11. PubMed
Mutant UBQLN2 promotes toxicity by modulating intrinsic self-assembly. Sharkey LM, Safren N, Pithadia AS, Gerson JE, Dulchavsky M, Fischer S, Patel R, Lantis G, Ashraf N, Kim JH, Meliki A, Minakawa EN, Barmada SJ, Ivanova MI, Paulson HL. Proc Natl Acad Sci U S A. 2018 Oct 30;115(44):E10495-E10504. doi: 10.1073/pnas.1810522115. Epub 2018 Oct 17. PubMed
Ubiquilins regulate autophagic flux through mTOR signalling and lysosomal acidification. Senturk M, Lin G, Zuo Z, Mao D, Watson E, Mikos AG, Bellen HJ. Nat Cell Biol. 2019 Mar;21(3):384-396. doi: 10.1038/s41556-019-0281-x. Epub 2019 Feb 25. PubMed
Autophagy and Ubiquitin-Proteasome System Coordinate to Regulate the Protein Quality Control of Neurodegenerative Disease-Associated DCTN1. Wang N, Ma Q, Peng P, Yu Y, Xu S, Wang G, Ying Z, Wang H. Neurotox Res. 2020 Jan;37(1):48-57. doi: 10.1007/s12640-019-00113-y. Epub 2019 Oct 25. PubMed
Amyotrophic lateral sclerosis-linked UBQLN2 mutants inhibit endoplasmic reticulum to Golgi transport, leading to Golgi fragmentation and ER stress. Halloran M, Ragagnin AMG, Vidal M, Parakh S, Yang S, Heng B, Grima N, Shahheydari H, Soo KY, Blair I, Guillemin GJ, Sundaramoorthy V, Atkin JD. Cell Mol Life Sci. 2019 Dec 4. pii: 10.1007/s00018-019-03394-w. doi: 10.1007/s00018-019-03394-w. PubMed
Ubiquilin-2 differentially regulates polyglutamine disease proteins. Gerson JE, Safren N, Fischer S, Patel R, Crowley EV, Welday JP, Windle AK, Barmada S, Paulson HL, Sharkey LM. Hum Mol Genet. 2020 Jul 18. pii: 5873245. doi: 10.1093/hmg/ddaa152. PubMed
The Impact of ALS-Associated Genes hnRNPA1, MATR3, VCP and UBQLN2 on the Severity of TDP-43 Aggregation. Bajc Cesnik A, Motaln H, Rogelj B. Cells. 2020 Jul 28;9(8). pii: cells9081791. doi: 10.3390/cells9081791. PubMed
Shared and divergent phase separation and aggregation properties of brain-expressed ubiquilins. Gerson JE, Linton H, Xing J, Sutter AB, Kakos FS, Ryou J, Liggans N, Sharkey LM, Safren N, Paulson HL, Ivanova MI. Sci Rep. 2021 Jan 11;11(1):287. doi: 10.1038/s41598-020-78775-4. PubMed
Disrupting the Balance of Protein Quality Control Protein UBQLN2 Accelerates Tau Proteinopathy. Gerson JE, Sandoval-Pistorius S, Welday JP, Rodriguez A, Gregory JD, Liggans N, Schache K, Li X, Trzeciakiewicz H, Barmada S, Sharkey LM, Paulson HL. J Neurosci. 2022 Mar 2;42(9):1845-1863. doi: 10.1523/JNEUROSCI.1116-21.2021. Epub 2022 Jan 26. PubMed
RTL8 promotes nuclear localization of UBQLN2 to subnuclear compartments associated with protein quality control. Mohan HM, Trzeciakiewicz H, Pithadia A, Crowley EV, Pacitto R, Safren N, Trotter B, Zhang C, Zhou X, Zhang Y, Basrur V, Paulson HL, Sharkey LM. Cell Mol Life Sci. 2022 Mar 5;79(3):176. doi: 10.1007/s00018-022-04170-z. PubMed
Ubiquilin-2 regulates pathological alpha-synuclein. Sandoval-Pistorius SS, Gerson JE, Liggans N, Ryou JH, Oak K, Li X, Negron-Rios KY, Fischer S, Barsh H, Crowley EV, Skinner ME, Sharkey LM, Barmada SJ, Paulson HL. Sci Rep. 2023 Jan 6;13(1):293. doi: 10.1038/s41598-022-26899-0. PubMed

If you have published an article using this material, please email us at to have your article added to this page.