pMH0001 Citations (25)
Originally described in: A Multiplexed Single-Cell CRISPR Screening Platform Enables Systematic Dissection of the Unfolded Protein Response.Adamson B, Norman TM, Jost M, Cho MY, Nunez JK, Chen Y, Villalta JE, Gilbert LA, Horlbeck MA, Hein MY, Pak RA, Gray AN, Gross CA, Dixit A, Parnas O, Regev A, Weissman JS Cell. 2016 Dec 15;167(7):1867-1882.e21. doi: 10.1016/j.cell.2016.11.048. PubMed Journal
Articles Citing pMH0001
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Components of genetic associations across 2,138 phenotypes in the UK Biobank highlight adipocyte biology. Tanigawa Y, Li J, Justesen JM, Horn H, Aguirre M, DeBoever C, Chang C, Narasimhan B, Lage K, Hastie T, Park CY, Bejerano G, Ingelsson E, Rivas MA. Nat Commun. 2019 Sep 6;10(1):4064. doi: 10.1038/s41467-019-11953-9. PubMed |
A curative combination cancer therapy achieves high fractional cell killing through low cross-resistance and drug additivity. Palmer AC, Chidley C, Sorger PK. Elife. 2019 Nov 19;8. pii: 50036. doi: 10.7554/eLife.50036. PubMed |
Targeted Perturb-seq enables genome-scale genetic screens in single cells. Schraivogel D, Gschwind AR, Milbank JH, Leonce DR, Jakob P, Mathur L, Korbel JO, Merten CA, Velten L, Steinmetz LM. Nat Methods. 2020 Jun;17(6):629-635. doi: 10.1038/s41592-020-0837-5. Epub 2020 Jun 1. PubMed |
Meningioma cells express primary cilia but do not transduce ciliary Hedgehog signals. Findakly S, Choudhury A, Daggubati V, Pekmezci M, Lang UE, Raleigh DR. Acta Neuropathol Commun. 2020 Jul 20;8(1):114. doi: 10.1186/s40478-020-00994-7. PubMed |
Genome-Scale Perturbation of Long Noncoding RNA Expression Using CRISPR Interference. Liu SJ, Horlbeck MA, Weissman JS, Lim DA. Methods Mol Biol. 2021;2254:323-338. doi: 10.1007/978-1-0716-1158-6_20. PubMed |
High-content imaging-based pooled CRISPR screens in mammalian cells.
Yan X, Stuurman N, Ribeiro SA, Tanenbaum ME, Horlbeck MA, Liem CR, Jost M, Weissman JS, Vale RD.
J Cell Biol. 2021 Feb 1;220(2). pii: 211696. doi: 10.1083/jcb.202008158.
PubMed
Associated Plasmids |
A CRISPR Competition Assay to Identify Cancer Genetic Dependencies. Girish V, Sheltzer JM. Bio Protoc. 2020 Jul 20;10(14):e3682. doi: 10.21769/BioProtoc.3682. eCollection 2020 Jul 20. PubMed |
Multiplex T-cell Stimulation Assay Utilizing a T-cell Activation Reporter-based Detection System.
Landry LG, Mann SE, Anderson AM, Nakayama M.
Bio Protoc. 2021 Jan 20;11(2):e3883. doi: 10.21769/BioProtoc.3883. eCollection 2021 Jan 20.
PubMed
Associated Plasmids |
CRISPRi/a Screening with Human iPSCs. Nishiga M, Qi LS, Wu JC. Methods Mol Biol. 2021;2320:261-281. doi: 10.1007/978-1-0716-1484-6_23. PubMed |
Ligation-assisted homologous recombination enables precise genome editing by deploying both MMEJ and HDR. Zhao Z, Shang P, Sage F, Geijsen N. Nucleic Acids Res. 2022 Jun 24;50(11):e62. doi: 10.1093/nar/gkac118. PubMed |
Meningioma DNA methylation groups identify biological drivers and therapeutic vulnerabilities. Choudhury A, Magill ST, Eaton CD, Prager BC, Chen WC, Cady MA, Seo K, Lucas CG, Casey-Clyde TJ, Vasudevan HN, Liu SJ, Villanueva-Meyer JE, Lam TC, Pu JK, Li LF, Leung GK, Swaney DL, Zhang MY, Chan JW, Qiu Z, Martin MV, Susko MS, Braunstein SE, Bush NAO, Schulte JD, Butowski N, Sneed PK, Berger MS, Krogan NJ, Perry A, Phillips JJ, Solomon DA, Costello JF, McDermott MW, Rich JN, Raleigh DR. Nat Genet. 2022 May;54(5):649-659. doi: 10.1038/s41588-022-01061-8. Epub 2022 May 9. PubMed |
SARS-CoV-2 Permissive glioblastoma cell line for high throughput antiviral screening. Vanhulle E, Stroobants J, Provinciael B, Camps A, Noppen S, Maes P, Vermeire K. Antiviral Res. 2022 Jul;203:105342. doi: 10.1016/j.antiviral.2022.105342. Epub 2022 May 18. PubMed |
Circadian lncRNA ADIRF-AS1 binds PBAF and regulates renal clear cell tumorigenesis. Brooks R, Monzy J, Aaron B, Zhang X, Kossenkov A, Hayden J, Keeney F, Speicher DW, Zhang L, Dang CV. Cell Rep. 2022 Oct 18;41(3):111514. doi: 10.1016/j.celrep.2022.111514. PubMed |
Systematic discovery and functional dissection of enhancers needed for cancer cell fitness and proliferation. Chen PB, Fiaux PC, Zhang K, Li B, Kubo N, Jiang S, Hu R, Rooholfada E, Wu S, Wang M, Wang W, McVicker G, Mischel PS, Ren B. Cell Rep. 2022 Nov 8;41(6):111630. doi: 10.1016/j.celrep.2022.111630. PubMed |
Maximizing CRISPRi efficacy and accessibility with dual-sgRNA libraries and optimal effectors.
Replogle JM, Bonnar JL, Pogson AN, Liem CR, Maier NK, Ding Y, Russell BJ, Wang X, Leng K, Guna A, Norman TM, Pak RA, Ramos DM, Ward ME, Gilbert LA, Kampmann M, Weissman JS, Jost M.
eLife. 2022 Dec 28;11:e81856. doi: 10.7554/eLife.81856.
PubMed
Associated Plasmids |
Oncogene-like addiction to aneuploidy in human cancers.
Girish V, Lakhani AA, Thompson SL, Scaduto CM, Brown LM, Hagenson RA, Sausville EL, Mendelson BE, Kandikuppa PK, Lukow DA, Yuan ML, Stevens EC, Lee SN, Schukken KM, Akalu SM, Vasudevan A, Zou C, Salovska B, Li W, Smith JC, Taylor AM, Martienssen RA, Liu Y, Sun R, Sheltzer JM.
Science. 2023 Jul 6:eadg4521. doi: 10.1126/science.adg4521.
PubMed
Associated Plasmids |
Translational fidelity screens in mammalian cells reveal eIF3 and eIF4G2 as regulators of start codon selectivity. She R, Luo J, Weissman JS. Nucleic Acids Res. 2023 Jul 7;51(12):6355-6369. doi: 10.1093/nar/gkad329. PubMed |
Selective Enhancer Dependencies in MYC -Intact and MYC -Rearranged Germinal Center B-cell Diffuse Large B-cell Lymphoma. Iyer AR, Gurumurthy A, Kodgule R, Aguilar AR, Saari T, Ramzan A, Rausch D, Gupta J, Hall CN, Runge JS, Weiss M, Rahmat M, Anyoha R, Fulco CP, Ghobrial IM, Engreitz J, Cieslik MP, Ryan RJH. bioRxiv. 2023 May 3:2023.05.02.538892. doi: 10.1101/2023.05.02.538892. Preprint. PubMed |
Spatial genomic, biochemical, and cellular mechanisms drive meningioma heterogeneity and evolution. Lucas CH, Mirchia K, Seo K, Najem H, Chen W, Zakimi N, Choudhury A, Liu SJ, Phillips J, Magill S, Horbinski C, Solomon D, Perry A, Vasudevan H, Heimberger A, Raleigh D. Res Sq [Preprint]. 2023 May 15:rs.3.rs-2921804. doi: 10.21203/rs.3.rs-2921804/v1. PubMed |
Systematic functional interrogation of SARS-CoV-2 host factors using Perturb-seq. Sunshine S, Puschnik AS, Replogle JM, Laurie MT, Liu J, Zha BS, Nunez JK, Byrum JR, McMorrow AH, Frieman MB, Winkler J, Qiu X, Rosenberg OS, Leonetti MD, Ye CJ, Weissman JS, DeRisi JL, Hein MY. Nat Commun. 2023 Oct 6;14(1):6245. doi: 10.1038/s41467-023-41788-4. PubMed |
ASCT2 is the primary serine transporter in cancer cells. Conger KO, Chidley C, Ozgurses ME, Zhao H, Kim Y, Semina SE, Burns P, Rawat V, Sheldon R, Ben-Sahra I, Frasor J, Sorger PK, DeNicola GM, Coloff JL. bioRxiv [Preprint]. 2023 Oct 11:2023.10.09.561530. doi: 10.1101/2023.10.09.561530. PubMed |
Functional interactions between neurofibromatosis tumor suppressors underlie Schwann cell tumor de-differentiation and treatment resistance. Vasudevan HN, Payne E, Delley CL, John Liu S, Mirchia K, Sale MJ, Lastella S, Nunez MS, Lucas CG, Eaton CD, Casey-Clyde T, Magill ST, Chen WC, Braunstein SE, Perry A, Jacques L, Reddy AT, Pekmezci M, Abate AR, McCormick F, Raleigh DR. Nat Commun. 2024 Jan 12;15(1):477. doi: 10.1038/s41467-024-44755-9. PubMed |
Improving prime editing with an endogenous small RNA-binding protein.
Yan J, Oyler-Castrillo P, Ravisankar P, Ward CC, Levesque S, Jing Y, Simpson D, Zhao A, Li H, Yan W, Goudy L, Schmidt R, Solley SC, Gilbert LA, Chan MM, Bauer DE, Marson A, Parsons LR, Adamson B.
Nature. 2024 Apr 3. doi: 10.1038/s41586-024-07259-6.
PubMed
Associated Plasmids |
A CRISPRi/a screening platform to study cellular nutrient transport in diverse microenvironments. Chidley C, Darnell AM, Gaudio BL, Lien EC, Barbeau AM, Vander Heiden MG, Sorger PK. Nat Cell Biol. 2024 May;26(5):825-838. doi: 10.1038/s41556-024-01402-1. Epub 2024 Apr 11. PubMed |
Nucleotide depletion promotes cell fate transitions by inducing DNA replication stress. Do BT, Hsu PP, Vermeulen SY, Wang Z, Hirz T, Abbott KL, Aziz N, Replogle JM, Bjelosevic S, Paolino J, Nelson SA, Block S, Darnell AM, Ferreira R, Zhang H, Milosevic J, Schmidt DR, Chidley C, Harris IS, Weissman JS, Pikman Y, Stegmaier K, Cheloufi S, Su XA, Sykes DB, Vander Heiden MG. Dev Cell. 2024 May 30:S1534-5807(24)00327-7. doi: 10.1016/j.devcel.2024.05.010. PubMed |
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