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pcDNA3-FLAG-LKB1 Citations (19)
Originally described in: The tumor suppressor LKB1 kinase directly activates AMP-activated kinase and regulates apoptosis in response to energy stress.Shaw RJ, Kosmatka M, Bardeesy N, Hurley RL, Witters LA, DePinho RA, Cantley LC Proc Natl Acad Sci U S A 2004 Mar 9;101(10):3329-35. Epub 2004 Feb 25. PubMed Journal
Articles Citing pcDNA3-FLAG-LKB1
Showing 1 to 10 of 19 entries
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Redefining the role of AMPK in autophagy and the energy stress response. Park JM, Lee DH, Kim DH. Nat Commun. 2023 May 24;14(1):2994. doi: 10.1038/s41467-023-38401-z. PubMed |
Functional assessment of somatic STK11 variants identified in primary human non-small cell lung cancers. Donnelly LL, Hogan TC, Lenahan SM, Nandagopal G, Eaton JG, Lebeau MA, McCann CL, Sarausky HM, Hampel KJ, Armstrong JD, Cameron MP, Sidiropoulos N, Deming P, Seward DJ. Carcinogenesis. 2021 Dec 31;42(12):1428-1438. doi: 10.1093/carcin/bgab104. PubMed |
Suppression of m6A mRNA modification by DNA hypermethylated ALKBH5 aggravates the oncological behavior of KRAS mutation/LKB1 loss lung cancer. Zhang D, Ning J, Okon I, Zheng X, Satyanarayana G, Song P, Xu S, Zou MH. Cell Death Dis. 2021 May 20;12(6):518. doi: 10.1038/s41419-021-03793-7. PubMed |
LKB1 Deficiency Renders NSCLC Cells Sensitive to ERK Inhibitors. Caiola E, Iezzi A, Tomanelli M, Bonaldi E, Scagliotti A, Colombo M, Guffanti F, Micotti E, Garassino MC, Minoli L, Scanziani E, Broggini M, Marabese M. J Thorac Oncol. 2020 Mar;15(3):360-370. doi: 10.1016/j.jtho.2019.10.009. Epub 2019 Oct 18. PubMed |
Hyaluronidase2 (Hyal2) modulates low shear stress-induced glycocalyx impairment via the LKB1/AMPK/NADPH oxidase-dependent pathway. Yang H, Zhu L, Chao Y, Gu Y, Kong X, Chen M, Ye P, Luo J, Chen S. J Cell Physiol. 2018 Dec;233(12):9701-9715. doi: 10.1002/jcp.26944. Epub 2018 Aug 5. PubMed |
Concurrent regulation of LKB1 and CaMKK2 in the activation of AMPK in castrate-resistant prostate cancer by a well-defined polyherbal mixture with anticancer properties. MacDonald AF, Bettaieb A, Donohoe DR, Alani DS, Han A, Zhao Y, Whelan J. BMC Complement Altern Med. 2018 Jun 18;18(1):188. doi: 10.1186/s12906-018-2255-0. PubMed |
LKB1, Salt-Inducible Kinases, and MEF2C Are Linked Dependencies in Acute Myeloid Leukemia.
Tarumoto Y, Lu B, Somerville TDD, Huang YH, Milazzo JP, Wu XS, Klingbeil O, El Demerdash O, Shi J, Vakoc CR.
Mol Cell. 2018 Feb 28. pii: S1097-2765(18)30109-6. doi: 10.1016/j.molcel.2018.02.011.
PubMed
Associated Plasmids |
The PLAG1-GDH1 Axis Promotes Anoikis Resistance and Tumor Metastasis through CamKK2-AMPK Signaling in LKB1-Deficient Lung Cancer. Jin L, Chun J, Pan C, Kumar A, Zhang G, Ha Y, Li D, Alesi GN, Kang Y, Zhou L, Yu WM, Magliocca KR, Khuri FR, Qu CK, Metallo C, Owonikoko TK, Kang S. Mol Cell. 2018 Jan 4;69(1):87-99.e7. doi: 10.1016/j.molcel.2017.11.025. Epub 2017 Dec 14. PubMed |
Liver kinase B1 restoration promotes exosome secretion and motility of lung cancer cells. Zhang C, Xiao X, Chen M, Aldharee H, Chen Y, Long W. Oncol Rep. 2018 Jan;39(1):376-382. doi: 10.3892/or.2017.6085. Epub 2017 Nov 9. PubMed |
Class III phosphatidylinositol-3-OH kinase controls epithelial integrity through endosomal LKB1 regulation. O'Farrell F, Lobert VH, Sneeggen M, Jain A, Katheder NS, Wenzel EM, Schultz SW, Tan KW, Brech A, Stenmark H, Rusten TE. Nat Cell Biol. 2017 Dec;19(12):1412-1423. doi: 10.1038/ncb3631. Epub 2017 Oct 30. PubMed |
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