pAAV-U6-sgRNA-CMV-GFP Citations (16)
Originally described in: The CRISPR/Cas9-created MDM2 T309G enhances vitreous-induced expression of MDM2 and proliferation and survival of cells.Duan Y, Ma G, Huang X, D'Amore PA, Zhang F, Lei H J Biol Chem. 2016 May 31. pii: jbc.M116.729467. PubMed Journal
Articles Citing pAAV-U6-sgRNA-CMV-GFP
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| CRISPR Activation Enhances In Vitro Potency of AAV Vectors Driven by Tissue-Specific Promoters. McDougald DS, Duong TT, Palozola KC, Marsh A, Papp TE, Mills JA, Zhou S, Bennett J. Mol Ther Methods Clin Dev. 2019 Mar 28;13:380-389. doi: 10.1016/j.omtm.2019.03.004. eCollection 2019 Jun 14. PubMed |
| Ube2v1 Positively Regulates Protein Aggregation by Modulating Ubiquitin Proteasome System Performance Partially Through K63 Ubiquitination. Xu N, Gulick J, Osinska H, Yu Y, McLendon PM, Shay-Winkler K, Robbins J, Yutzey KE. Circ Res. 2020 Mar 27;126(7):907-922. doi: 10.1161/CIRCRESAHA.119.316444. Epub 2020 Feb 21. PubMed |
| Injury triggers fascia fibroblast collective cell migration to drive scar formation through N-cadherin. Jiang D, Christ S, Correa-Gallegos D, Ramesh P, Kalgudde Gopal S, Wannemacher J, Mayr CH, Lupperger V, Yu Q, Ye H, Muck-Hausl M, Rajendran V, Wan L, Liu J, Mirastschijski U, Volz T, Marr C, Schiller HB, Rinkevich Y. Nat Commun. 2020 Nov 6;11(1):5653. doi: 10.1038/s41467-020-19425-1. PubMed |
| AAV-mediated in vivo genome editing in vascular endothelial cells. Wu W, Yang Y, Yao F, Dong L, Xia X, Zhang S, Lei H. Methods. 2020 Dec 9. pii: S1046-2023(20)30263-2. doi: 10.1016/j.ymeth.2020.12.001. PubMed |
| Cul3 regulates cytoskeleton protein homeostasis and cell migration during a critical window of brain development. Morandell J, Schwarz LA, Basilico B, Tasciyan S, Dimchev G, Nicolas A, Sommer C, Kreuzinger C, Dotter CP, Knaus LS, Dobler Z, Cacci E, Schur FKM, Danzl JG, Novarino G. Nat Commun. 2021 May 24;12(1):3058. doi: 10.1038/s41467-021-23123-x. PubMed |
Targeted regulation of transcription in primary cells using CRISPRa and CRISPRi.
Jensen TI, Mikkelsen NS, Gao Z, Fosselteder J, Pabst G, Axelgaard E, Laustsen A, Konig S, Reinisch A, Bak RO.
Genome Res. 2021 Nov;31(11):2120-2130. doi: 10.1101/gr.275607.121. Epub 2021 Aug 18.
PubMed
Associated Plasmids |
| Traumatic-noise-induced hair cell death and hearing loss is mediated by activation of CaMKKbeta. Wu F, Hill K, Fang Q, He Z, Zheng H, Wang X, Xiong H, Sha SH. Cell Mol Life Sci. 2022 Apr 19;79(5):249. doi: 10.1007/s00018-022-04268-4. PubMed |
| The Hippo pathway links adipocyte plasticity to adipose tissue fibrosis. Shen H, Huang X, Zhao Y, Wu D, Xue K, Yao J, Wang Y, Tang N, Qiu Y. Nat Commun. 2022 Oct 13;13(1):6030. doi: 10.1038/s41467-022-33800-0. PubMed |
| Gene editing of Duchenne muscular dystrophy using biomineralization-based spCas9 variant nanoparticles. Li S, Du M, Deng J, Deng G, Li J, Song Z, Han H. Acta Biomater. 2022 Dec;154:597-607. doi: 10.1016/j.actbio.2022.10.015. Epub 2022 Oct 13. PubMed |
| Heterozygous mutations in SOX2 may cause idiopathic hypogonadotropic hypogonadism via dominant-negative mechanisms. Cassin J, Stamou MI, Keefe KW, Sung KE, Bojo CC, Tonsfeldt KJ, Rojas RA, Ferreira Lopes V, Plummer L, Salnikov KB, Keefe DL Jr, Ozata M, Genel M, Georgopoulos NA, Hall JE, Crowley WF Jr, Seminara SB, Mellon PL, Balasubramanian R. JCI Insight. 2023 Feb 8;8(3):e164324. doi: 10.1172/jci.insight.164324. PubMed |
An AAV-CRISPR/Cas9 strategy for gene editing across divergent rodent species: Targeting neural oxytocin receptors as a proof of concept.
Boender AJ, Boon M, Albers HE, Eck SR, Fricker BA, Kelly AM, LeDoux JE, Motta SC, Shrestha P, Taylor JH, Trainor BC, Triana-Del Rio R, Young LJ.
Sci Adv. 2023 Jun 2;9(22):eadf4950. doi: 10.1126/sciadv.adf4950. Epub 2023 May 31.
PubMed
Associated Plasmids |
| PE-STOP: A versatile tool for installing nonsense substitutions amenable for precise reversion. Song Z, Zhang G, Huang S, Liu Y, Li G, Zhou X, Sun J, Gao P, Chen Y, Huang X, Liu J, Wang X. J Biol Chem. 2023 Aug;299(8):104942. doi: 10.1016/j.jbc.2023.104942. Epub 2023 Jun 19. PubMed |
| Scalable, cell type-selective, AAV-based in vivo CRISPR screening in the mouse brain. Ramani B, Rose IVL, Pan A, Tian R, Ma K, Palop JJ, Kampmann M. bioRxiv [Preprint]. 2023 Jun 27:2023.06.13.544831. doi: 10.1101/2023.06.13.544831. PubMed |
| Transcriptional repression of beige fat innervation via a YAP/TAZ-S100B axis. Huang X, Li X, Shen H, Zhao Y, Zhou Z, Wang Y, Yao J, Xue K, Wu D, Qiu Y. Nat Commun. 2023 Nov 4;14(1):7102. doi: 10.1038/s41467-023-43021-8. PubMed |
| N(G) ,N(G) -Dimethylarginine Dimethylaminohydrolase 1 Expression Is Dispensable for Cold- or Diet-Induced Thermogenesis. Park MJ, Lee J, Bagon BB, Matienzo ME, Lim S, Kim K, Lee CM, Wu J, Kim DI. Adv Biol (Weinh). 2024 Feb;8(2):e2300192. doi: 10.1002/adbi.202300192. Epub 2024 Jan 2. PubMed |
| Rapid in vivo evaluation system for cholestasis-related genes in mice with humanized bile acid profiles. Wakasa K, Tamura R, Osaka S, Takei H, Asai A, Nittono H, Kusuhara H, Hayashi H. Hepatol Commun. 2024 Mar 22;8(4):e0382. doi: 10.1097/HC9.0000000000000382. eCollection 2024 Apr 1. PubMed |
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