pMRX-IP-GFP-LC3-RFP Citations (31)

Originally described in: An Autophagic Flux Probe that Releases an Internal Control.
Kaizuka T, Morishita H, Hama Y, Tsukamoto S, Matsui T, Toyota Y, Kodama A, Ishihara T, Mizushima T, Mizushima N Mol Cell. 2016 Nov 17;64(4):835-849. doi: 10.1016/j.molcel.2016.09.037. Epub 2016 Nov 3. PubMed Journal

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Articles Citing pMRX-IP-GFP-LC3-RFP

Articles
Autophagy impairment mediated by S-nitrosation of ATG4B leads to neurotoxicity in response to hyperglycemia. Li Y, Zhang Y, Wang L, Wang P, Xue Y, Li X, Qiao X, Zhang X, Xu T, Liu G, Li P, Chen C. Autophagy. 2017 Jul 3;13(7):1145-1160. doi: 10.1080/15548627.2017.1320467. PubMed
PKM1 Confers Metabolic Advantages and Promotes Cell-Autonomous Tumor Cell Growth. Morita M, Sato T, Nomura M, Sakamoto Y, Inoue Y, Tanaka R, Ito S, Kurosawa K, Yamaguchi K, Sugiura Y, Takizaki H, Yamashita Y, Katakura R, Sato I, Kawai M, Okada Y, Watanabe H, Kondoh G, Matsumoto S, Kishimoto A, Obata M, Matsumoto M, Fukuhara T, Motohashi H, Suematsu M, Komatsu M, Nakayama KI, Watanabe T, Soga T, Shima H, Maemondo M, Tanuma N. Cancer Cell. 2018 Mar 12;33(3):355-367.e7. doi: 10.1016/j.ccell.2018.02.004. PubMed
Isoscoparins R and S, two new ent-clerodane diterpenoids from Isodon scoparius. Li XR, Fu Q, Zhou M, Hu K, Du X, Li XN, Sun HD, Yue JB, Zhang HB, Puno PT. J Asian Nat Prod Res. 2018 Jun 6:1-8. doi: 10.1080/10286020.2018.1481054. PubMed
Subcellular Hsp70 Inhibitors Promote Cancer Cell Death via Different Mechanisms. Park SH, Baek KH, Shin I, Shin I. Cell Chem Biol. 2018 Oct 18;25(10):1242-1254.e8. doi: 10.1016/j.chembiol.2018.06.010. Epub 2018 Jul 26. PubMed
Complement Component C3 Is Highly Expressed in Human Pancreatic Islets and Prevents beta Cell Death via ATG16L1 Interaction and Autophagy Regulation. King BC, Kulak K, Krus U, Rosberg R, Golec E, Wozniak K, Gomez MF, Zhang E, O'Connell DJ, Renstrom E, Blom AM. Cell Metab. 2019 Jan 8;29(1):202-210.e6. doi: 10.1016/j.cmet.2018.09.009. Epub 2018 Oct 4. PubMed
Mitochondrial calcium dysfunction contributes to autophagic cell death induced by MPP(+) via AMPK pathway. Zhao M, Chen J, Mao K, She H, Ren Y, Gui C, Wu X, Zou F, Li W. Biochem Biophys Res Commun. 2019 Feb 5;509(2):390-394. doi: 10.1016/j.bbrc.2018.12.148. Epub 2018 Dec 26. PubMed
PRRSV activates lipophagy to facilitate viral replication through down-regulation of NDRG1 expression. Wang J, Liu JY, Shao KY, Han YQ, Li GL, Ming SL, Su BQ, Du YK, Liu ZH, Zhang GP, Yang GY, Chu BB. J Virol. 2019 Jun 12. pii: JVI.00526-19. doi: 10.1128/JVI.00526-19. PubMed
TRP14 promotes resistance to cisplatin by inducing autophagy in ovarian cancer. Tan WX, Xu TM, Zhou ZL, Lv XJ, Liu J, Zhang WJ, Cui MH. Oncol Rep. 2019 Aug 2. doi: 10.3892/or.2019.7258. PubMed
The RING-type E3 ligase RNF186 ubiquitinates Sestrin-2 and thereby controls nutrient sensing. Lear TB, Lockwood KC, Ouyang Y, Evankovich JW, Larsen MB, Lin B, Liu Y, Chen BB. J Biol Chem. 2019 Nov 8;294(45):16527-16534. doi: 10.1074/jbc.AC119.010671. Epub 2019 Oct 4. PubMed
Prolyl oligopeptidase inhibition activates autophagy via protein phosphatase 2A. Svarcbahs R, Jantti M, Kilpelainen T, Julku UH, Urvas L, Kivioja S, Norrbacka S, Myohanen TT. Pharmacol Res. 2020 Jan;151:104558. doi: 10.1016/j.phrs.2019.104558. Epub 2019 Nov 20. PubMed
The effect of prolyl oligopeptidase inhibitors on alpha-synuclein aggregation and autophagy cannot be predicted by their inhibitory efficacy. Kilpelainen TP, Hellinen L, Vrijdag J, Yan X, Svarcbahs R, Vellonen KS, Lambeir AM, Huttunen H, Urtti A, Wallen EAA, Myohanen TT. Biomed Pharmacother. 2020 Aug;128:110253. doi: 10.1016/j.biopha.2020.110253. Epub 2020 May 22. PubMed
Poly (ADP-ribose) polymerase 1 inhibition prevents neurodegeneration and promotes alpha-synuclein degradation via transcription factor EB-dependent autophagy in mutant alpha-synucleinA53T model of Parkinson's disease. Mao K, Chen J, Yu H, Li H, Ren Y, Wu X, Wen Y, Zou F, Li W. Aging Cell. 2020 Jun;19(6):e13163. doi: 10.1111/acel.13163. Epub 2020 May 31. PubMed
ULK1-ATG13 and their mitotic phospho-regulation by CDK1 connect autophagy to cell cycle. Li Z, Tian X, Ji X, Wang J, Chen H, Wang D, Zhang X. PLoS Biol. 2020 Jun 9;18(6):e3000288. doi: 10.1371/journal.pbio.3000288. eCollection 2020 Jun. PubMed
Deficiency of C-X-C chemokine receptor type 5 (CXCR5) gene causes dysfunction of retinal pigment epithelium cells. Lennikov A, Mukwaya A, Saddala MS, Huang H. Lab Invest. 2021 Feb;101(2):228-244. doi: 10.1038/s41374-020-00491-4. Epub 2020 Sep 29. PubMed
TLR9 Binding to Beclin 1 and Mitochondrial SIRT3 by a Sodium-Glucose Co-Transporter 2 Inhibitor Protects the Heart from Doxorubicin Toxicity. Wang CY, Chen CC, Lin MH, Su HT, Ho MY, Yeh JK, Tsai ML, Hsieh IC, Wen MS. Biology (Basel). 2020 Oct 29;9(11). pii: biology9110369. doi: 10.3390/biology9110369. PubMed
Assessing methods to quantitatively validate TGFbeta-dependent autophagy. Trelford CB, Di Guglielmo GM. Biol Open. 2020 Nov 23;9(11). pii: bio.055103. doi: 10.1242/bio.055103. PubMed
Maintenance of neural stem-progenitor cells by the lysosomal biosynthesis regulators TFEB and TFE3 in the embryonic mouse telencephalon. Yuizumi N, Harada Y, Kuniya T, Sunabori T, Koike M, Wakabayashi M, Ishihama Y, Suzuki Y, Kawaguchi D, Gotoh Y. Stem Cells. 2021 Jul;39(7):929-944. doi: 10.1002/stem.3359. Epub 2021 Mar 10. PubMed
MCOLN1/TRPML1 finely controls oncogenic autophagy in cancer by mediating zinc influx. Qi J, Xing Y, Liu Y, Wang MM, Wei X, Sui Z, Ding L, Zhang Y, Lu C, Fei YH, Liu N, Chen R, Wu M, Wang L, Zhong Z, Wang T, Liu Y, Wang Y, Liu J, Xu H, Guo F, Wang W. Autophagy. 2021 Dec;17(12):4401-4422. doi: 10.1080/15548627.2021.1917132. Epub 2021 Apr 23. PubMed
Minimized combinatorial CRISPR screens identify genetic interactions in autophagy. Diehl V, Wegner M, Grumati P, Husnjak K, Schaubeck S, Gubas A, Shah VJ, Polat IH, Langschied F, Prieto-Garcia C, Muller K, Kalousi A, Ebersberger I, Brandts CH, Dikic I, Kaulich M. Nucleic Acids Res. 2021 Jun 4;49(10):5684-5704. doi: 10.1093/nar/gkab309. PubMed
TGFbeta promotes fibrosis by MYST1-dependent epigenetic regulation of autophagy. Zehender A, Li YN, Lin NY, Stefanica A, Nuchel J, Chen CW, Hsu HH, Zhu H, Ding X, Huang J, Shen L, Gyorfi AH, Soare A, Rauber S, Bergmann C, Ramming A, Plomann M, Eckes B, Schett G, Distler JHW. Nat Commun. 2021 Jul 20;12(1):4404. doi: 10.1038/s41467-021-24601-y. PubMed
Stimulating TRPM7 suppresses cancer cell proliferation and metastasis by inhibiting autophagy. Xing Y, Wei X, Wang MM, Liu Y, Sui Z, Wang X, Zhang Y, Fei YH, Jiang Y, Lu C, Zhang P, Chen R, Liu N, Wu M, Ding L, Wang Y, Guo F, Cao JL, Qi J, Wang W. Cancer Lett. 2022 Jan 28;525:179-197. doi: 10.1016/j.canlet.2021.10.043. Epub 2021 Nov 6. PubMed
Autophagy inhibition mediated by MCOLN1/TRPML1 suppresses cancer metastasis via regulating a ROS-driven TP53/p53 pathway. Xing Y, Wei X, Liu Y, Wang MM, Sui Z, Wang X, Zhu W, Wu M, Lu C, Fei YH, Jiang Y, Zhang Y, Wang Y, Guo F, Cao JL, Qi J, Wang W. Autophagy. 2022 Aug;18(8):1932-1954. doi: 10.1080/15548627.2021.2008752. Epub 2021 Dec 8. PubMed
A clinically compatible drug-screening platform based on organotypic cultures identifies vulnerabilities to prevent and treat brain metastasis. Zhu L, Retana D, Garcia-Gomez P, Alvaro-Espinosa L, Priego N, Masmudi-Martin M, Yebra N, Miarka L, Hernandez-Encinas E, Blanco-Aparicio C, Martinez S, Sobrino C, Ajenjo N, Artiga MJ, Ortega-Paino E, Torres-Ruiz R, Rodriguez-Perales S, Soffietti R, Bertero L, Cassoni P, Weiss T, Munoz J, Sepulveda JM, Gonzalez-Leon P, Jimenez-Roldan L, Moreno LM, Esteban O, Perez-Nunez A, Hernandez-Lain A, Toldos O, Ruano Y, Alcazar L, Blasco G, Fernandez-Alen J, Caleiras E, Lafarga M, Megias D, Grana-Castro O, Nor C, Taylor MD, Young LS, Vareslija D, Cosgrove N, Couch FJ, Cusso L, Desco M, Mouron S, Quintela-Fandino M, Weller M, Pastor J, Valiente M. EMBO Mol Med. 2022 Mar 7;14(3):e14552. doi: 10.15252/emmm.202114552. Epub 2022 Feb 17. PubMed
Follicular lymphoma-associated mutations in the V-ATPase chaperone VMA21 activate autophagy creating a targetable dependency. Wang F, Yang Y, Boudagh G, Eskelinen EL, Klionsky DJ, Malek SN. Autophagy. 2022 Aug;18(8):1982-2000. doi: 10.1080/15548627.2022.2050663. Epub 2022 Mar 24. PubMed
EGCG Restricts PRRSV Proliferation by Disturbing Lipid Metabolism. Yu PW, Fu PF, Zeng L, Qi YL, Li XQ, Wang Q, Yang GY, Li HW, Wang J, Chu BB, Wang MD. Microbiol Spectr. 2022 Apr 27;10(2):e0227621. doi: 10.1128/spectrum.02276-21. Epub 2022 Apr 11. PubMed
Starvation after infection restricts enterovirus D68 replication. Jassey A, Wagner MA, Galitska G, Paudel B, Miller K, Jackson WT. Autophagy. 2022 Apr 21:1-14. doi: 10.1080/15548627.2022.2062888. PubMed
Integrated regulation of stress responses, autophagy and survival by altered intracellular iron stores. Wang Y, Wang M, Liu Y, Tao H, Banerjee S, Srinivasan S, Nemeth E, Czaja MJ, He P. Redox Biol. 2022 Jul 14;55:102407. doi: 10.1016/j.redox.2022.102407. PubMed
Tex2 is required for lysosomal functions at TMEM55-dependent ER membrane contact sites. Du Y, Chang W, Gao L, Deng L, Ji WK. J Cell Biol. 2023 Apr 3;222(4):e202205133. doi: 10.1083/jcb.202205133. Epub 2023 Jan 27. PubMed
Autophagy dictates sensitivity to PRMT5 inhibitor in breast cancer. Brobbey C, Yin S, Liu L, Ball LE, Howe PH, Delaney JR, Gan W. Sci Rep. 2023 Jul 3;13(1):10752. doi: 10.1038/s41598-023-37706-9. PubMed
CRISPR/Cas9-mediated inactivation of miR-34a and miR-34b/c in HCT116 colorectal cancer cells: comprehensive characterization after exposure to 5-FU reveals EMT and autophagy as key processes regulated by miR-34. Huang Z, Kaller M, Hermeking H. Cell Death Differ. 2023 Aug;30(8):2017-2034. doi: 10.1038/s41418-023-01193-2. Epub 2023 Jul 24. PubMed
Autophagy preferentially degrades non-fibrillar polyQ aggregates. Zhao DY, Bauerlein FJB, Saha I, Hartl FU, Baumeister W, Wilfling F. Mol Cell. 2024 May 16;84(10):1980-1994.e8. doi: 10.1016/j.molcel.2024.04.018. PubMed

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