pUMVC Citations (99)
Originally described in: Lentivirus-delivered stable gene silencing by RNAi in primary cells.Stewart SA, Dykxhoorn DM, Palliser D, Mizuno H, Yu EY, An DS, Sabatini DM, Chen IS, Hahn WC, Sharp PA, Weinberg RA, Novina CD RNA 2003 Apr;9(4):493-501. PubMed Journal
Articles Citing pUMVC
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| Enhanced generation of induced pluripotent stem cells from a subpopulation of human fibroblasts. Byrne JA, Nguyen HN, Reijo Pera RA. PLoS One. 2009 Sep 23;4(9):e7118. doi: 10.1371/journal.pone.0007118. PubMed |
| Generation of induced pluripotent stem cells from neural stem cells. Kim JB, Zaehres H, Arauzo-Bravo MJ, Scholer HR. Nat Protoc. 2009;4(10):1464-70. doi: 10.1038/nprot.2009.173. Epub 2009 Sep 17. PubMed |
| Mouse and human induced pluripotent stem cells as a source for multipotent Isl1+ cardiovascular progenitors. Moretti A, Bellin M, Jung CB, Thies TM, Takashima Y, Bernshausen A, Schiemann M, Fischer S, Moosmang S, Smith AG, Lam JT, Laugwitz KL. FASEB J. 2010 Mar;24(3):700-11. doi: 10.1096/fj.09-139477. Epub 2009 Oct 22. PubMed |
| Reprogramming of human fibroblasts to induced pluripotent stem cells under xeno-free conditions. RodrÃguez-Pizà I, Richaud-Patin Y, Vassena R, González F, Barrero MJ, Veiga A, Raya A, Belmonte JC. Stem Cells. 2010 Jan . 28(1):36-44. PubMed |
Large intergenic non-coding RNA-RoR modulates reprogramming of human induced pluripotent stem cells.
Loewer S, Cabili MN, Guttman M, Loh YH, Thomas K, Park IH, Garber M, Curran M, Onder T, Agarwal S, Manos PD, Datta S, Lander ES, Schlaeger TM, Daley GQ, Rinn JL.
Nat Genet. 2010 Dec;42(12):1113-7. Epub 2010 Nov 7.
PubMed
Associated Plasmids |
| Feeder-dependent and feeder-independent iPS cell derivation from human and mouse adipose stem cells. Sugii S, Kida Y, Berggren WT, Evans RM. Nat Protoc. 2011 Mar;6(3):346-58. doi: 10.1038/nprot.2010.199. Epub 2011 Feb 24. PubMed |
| Generation of induced pluripotent stem cell lines from human fibroblasts via retroviral gene transfer. Miller JD, Schlaeger TM. Methods Mol Biol. 2011;767:55-65. doi: 10.1007/978-1-61779-201-4_5. PubMed |
| FGF signalling inhibits neural induction in human embryonic stem cells. Greber B, Coulon P, Zhang M, Moritz S, Frank S, Muller-Molina AJ, Arauzo-Bravo MJ, Han DW, Pape HC, Scholer HR. EMBO J. 2011 Nov 15;30(24):4874-84. doi: 10.1038/emboj.2011.407. PubMed |
| Small molecule-assisted, line-independent maintenance of human pluripotent stem cells in defined conditions. Frank S, Zhang M, Scholer HR, Greber B. PLoS One. 2012;7(7):e41958. doi: 10.1371/journal.pone.0041958. Epub 2012 Jul 30. PubMed |
| Calcium-permeable alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid receptors trigger neuronal nitric-oxide synthase activation to promote nerve cell death in an Src kinase-dependent fashion. Socodato R, Santiago FN, Portugal CC, Domingues AF, Santiago AR, Relvas JB, Ambrosio AF, Paes-de-Carvalho R. J Biol Chem. 2012 Nov 9;287(46):38680-94. doi: 10.1074/jbc.M112.353961. Epub 2012 Sep 19. PubMed |
| Hypertonic stress promotes autophagy and microtubule-dependent autophagosomal clusters. Nunes P, Ernandez T, Roth I, Qiao X, Strebel D, Bouley R, Charollais A, Ramadori P, Foti M, Meda P, Feraille E, Brown D, Hasler U. Autophagy. 2013 Apr;9(4):550-67. doi: 10.4161/auto.23662. Epub 2013 Feb 4. PubMed |
| Genetic correction of a LRRK2 mutation in human iPSCs links parkinsonian neurodegeneration to ERK-dependent changes in gene expression. Reinhardt P, Schmid B, Burbulla LF, Schondorf DC, Wagner L, Glatza M, Hoing S, Hargus G, Heck SA, Dhingra A, Wu G, Muller S, Brockmann K, Kluba T, Maisel M, Kruger R, Berg D, Tsytsyura Y, Thiel CS, Psathaki OE, Klingauf J, Kuhlmann T, Klewin M, Muller H, Gasser T, Scholer HR, Sterneckert J. Cell Stem Cell. 2013 Mar 7;12(3):354-67. doi: 10.1016/j.stem.2013.01.008. PubMed |
| Derivation and expansion using only small molecules of human neural progenitors for neurodegenerative disease modeling. Reinhardt P, Glatza M, Hemmer K, Tsytsyura Y, Thiel CS, Hoing S, Moritz S, Parga JA, Wagner L, Bruder JM, Wu G, Schmid B, Ropke A, Klingauf J, Schwamborn JC, Gasser T, Scholer HR, Sterneckert J. PLoS One. 2013;8(3):e59252. doi: 10.1371/journal.pone.0059252. Epub 2013 Mar 22. PubMed |
| IQGAP1 binds to estrogen receptor-alpha and modulates its function. Erdemir HH, Li Z, Sacks DB. J Biol Chem. 2014 Mar 28;289(13):9100-12. doi: 10.1074/jbc.M114.553511. Epub 2014 Feb 18. PubMed |
| A differential role for CXCR4 in the regulation of normal versus malignant breast stem cell activity. Ablett MP, O'Brien CS, Sims AH, Farnie G, Clarke RB. Oncotarget. 2014 Feb 15;5(3):599-612. PubMed |
| Cooperation of tyrosine kinase receptor TrkB and epidermal growth factor receptor signaling enhances migration and dispersal of lung tumor cells. Gotz R, Sendtner M. PLoS One. 2014 Jun 24;9(6):e100944. doi: 10.1371/journal.pone.0100944. eCollection 2014. PubMed |
| The novel organic arsenical darinaparsin induces MAPK-mediated and SHP1-dependent cell death in T-cell lymphoma and Hodgkin lymphoma cells and human xenograft models. Ravi D, Bhalla S, Gartenhaus RB, Crombie J, Kandela I, Sharma J, Mazar A, Evens AM. Clin Cancer Res. 2014 Dec 1;20(23):6023-33. doi: 10.1158/1078-0432.CCR-14-1532. Epub 2014 Oct 14. PubMed |
| c-Src function is necessary and sufficient for triggering microglial cell activation. Socodato R, Portugal CC, Domith I, Oliveira NA, Coreixas VS, Loiola EC, Martins T, Santiago AR, Paes-de-Carvalho R, Ambrosio AF, Relvas JB. Glia. 2015 Mar;63(3):497-511. doi: 10.1002/glia.22767. Epub 2014 Nov 24. PubMed |
| c-Src deactivation by the polyphenol 3-O-caffeoylquinic acid abrogates reactive oxygen species-mediated glutamate release from microglia and neuronal excitotoxicity. Socodato R, Portugal CC, Canedo T, Domith I, Oliveira NA, Paes-de-Carvalho R, Relvas JB, Cossenza M. Free Radic Biol Med. 2015 Feb;79:45-55. doi: 10.1016/j.freeradbiomed.2014.11.019. Epub 2014 Dec 5. PubMed |
| Progerin expression disrupts critical adult stem cell functions involved in tissue repair. Pacheco LM, Gomez LA, Dias J, Ziebarth NM, Howard GA, Schiller PC. Aging (Albany NY). 2014 Dec;6(12):1049-63. PubMed |
| ANKS6 is the critical activator of NEK8 kinase in embryonic situs determination and organ patterning. Czarnecki PG, Gabriel GC, Manning DK, Sergeev M, Lemke K, Klena NT, Liu X, Chen Y, Li Y, San Agustin JT, Garnaas MK, Francis RJ, Tobita K, Goessling W, Pazour GJ, Lo CW, Beier DR, Shah JV. Nat Commun. 2015 Jan 20;6:6023. doi: 10.1038/ncomms7023. PubMed |
| DNA damage response factors from diverse pathways, including DNA crosslink repair, mediate alternative end joining. Howard SM, Yanez DA, Stark JM. PLoS Genet. 2015 Jan 28;11(1):e1004943. doi: 10.1371/journal.pgen.1004943. eCollection 2015 Jan. PubMed |
Identification of an oncogenic RAB protein.
Wheeler DB, Zoncu R, Root DE, Sabatini DM, Sawyers CL.
Science. 2015 Oct 9;350(6257):211-7. doi: 10.1126/science.aaa4903. Epub 2015 Sep 3.
PubMed
Associated Plasmids |
| Human iPS cell model of type 3 long QT syndrome recapitulates drug-based phenotype correction. Malan D, Zhang M, Stallmeyer B, Muller J, Fleischmann BK, Schulze-Bahr E, Sasse P, Greber B. Basic Res Cardiol. 2016 Mar;111(2):14. doi: 10.1007/s00395-016-0530-0. Epub 2016 Jan 23. PubMed |
| Opposing Roles of JNK and p38 in Lymphangiogenesis in Melanoma. Puujalka E, Heinz M, Hoesel B, Friedl P, Schweighofer B, Wenzina J, Pirker C, Schmid JA, Loewe R, Wagner EF, Berger W, Petzelbauer P. J Invest Dermatol. 2016 May;136(5):967-77. doi: 10.1016/j.jid.2016.01.020. Epub 2016 Jan 30. PubMed |
| Characterization of Two-Pore Channel 2 by Nuclear Membrane Electrophysiology. Lee CS, Tong BC, Cheng CW, Hung HC, Cheung KH. Sci Rep. 2016 Feb 3;6:20282. doi: 10.1038/srep20282. PubMed |
| Phosphorylation-Dependent Regulation of the DNA Damage Response of Adaptor Protein KIBRA in Cancer Cells. Mavuluri J, Beesetti S, Surabhi R, Kremerskothen J, Venkatraman G, Rayala SK. Mol Cell Biol. 2016 Apr 15;36(9):1354-65. doi: 10.1128/MCB.01004-15. Print 2016 May 1. PubMed |
| Dysregulation of miRNA-9 in a Subset of Schizophrenia Patient-Derived Neural Progenitor Cells. Topol A, Zhu S, Hartley BJ, English J, Hauberg ME, Tran N, Rittenhouse CA, Simone A, Ruderfer DM, Johnson J, Readhead B, Hadas Y, Gochman PA, Wang YC, Shah H, Cagney G, Rapoport J, Gage FH, Dudley JT, Sklar P, Mattheisen M, Cotter D, Fang G, Brennand KJ. Cell Rep. 2016 May 3;15(5):1024-36. doi: 10.1016/j.celrep.2016.03.090. Epub 2016 Apr 21. PubMed |
| Familial Alzheimer's disease-associated presenilin 1 mutants promote gamma-secretase cleavage of STIM1 to impair store-operated Ca2+ entry. Tong BC, Lee CS, Cheng WH, Lai KO, Foskett JK, Cheung KH. Sci Signal. 2016 Sep 6;9(444):ra89. doi: 10.1126/scisignal.aaf1371. PubMed |
| Antigen Targeting to Human HLA Class II Molecules Increases Efficacy of DNA Vaccination. Grodeland G, Fredriksen AB, Loset GA, Vikse E, Fugger L, Bogen B. J Immunol. 2016 Nov 1;197(9):3575-3585. Epub 2016 Sep 26. PubMed |
| Merkel Cell Polyomavirus Small T Antigen Promotes Pro-Glycolytic Metabolic Perturbations Required for Transformation. Berrios C, Padi M, Keibler MA, Park DE, Molla V, Cheng J, Lee SM, Stephanopoulos G, Quackenbush J, DeCaprio JA. PLoS Pathog. 2016 Nov 23;12(11):e1006020. doi: 10.1371/journal.ppat.1006020. eCollection 2016 Nov. PubMed |
| Tuberous sclerosis complex inactivation disrupts melanogenesis via mTORC1 activation. Cao J, Tyburczy ME, Moss J, Darling TN, Widlund HR, Kwiatkowski DJ. J Clin Invest. 2017 Jan 3;127(1):349-364. doi: 10.1172/JCI84262. Epub 2016 Dec 5. PubMed |
| Dopamine promotes NMDA receptor hypofunction in the retina through D1 receptor-mediated Csk activation, Src inhibition and decrease of GluN2B phosphorylation. Socodato R, Santiago FN, Portugal CC, Domith I, Encarnacao TG, Loiola EC, Ventura AL, Cossenza M, Relvas JB, Castro NG, Paes-de-Carvalho R. Sci Rep. 2017 Jan 18;7:40912. doi: 10.1038/srep40912. PubMed |
| Integrin-beta4 identifies cancer stem cell-enriched populations of partially mesenchymal carcinoma cells. Bierie B, Pierce SE, Kroeger C, Stover DG, Pattabiraman DR, Thiru P, Liu Donaher J, Reinhardt F, Chaffer CL, Keckesova Z, Weinberg RA. Proc Natl Acad Sci U S A. 2017 Mar 21;114(12):E2337-E2346. doi: 10.1073/pnas.1618298114. Epub 2017 Mar 7. PubMed |
| Susceptibility of Human Oral Squamous Cell Carcinoma (OSCC) H103 and H376 cell lines to Retroviral OSKM mediated reprogramming. Verusingam ND, Yeap SK, Ky H, Paterson IC, Khoo SP, Cheong SK, Ong AHK, Kamarul T. PeerJ. 2017 Apr 13;5:e3174. doi: 10.7717/peerj.3174. eCollection 2017. PubMed |
| TAM Receptors Are Not Required for Zika Virus Infection in Mice. Hastings AK, Yockey LJ, Jagger BW, Hwang J, Uraki R, Gaitsch HF, Parnell LA, Cao B, Mysorekar IU, Rothlin CV, Fikrig E, Diamond MS, Iwasaki A. Cell Rep. 2017 Apr 18;19(3):558-568. doi: 10.1016/j.celrep.2017.03.058. PubMed |
| Defects in autophagosome-lysosome fusion underlie Vici syndrome, a neurodevelopmental disorder with multisystem involvement. Hori I, Otomo T, Nakashima M, Miya F, Negishi Y, Shiraishi H, Nonoda Y, Magara S, Tohyama J, Okamoto N, Kumagai T, Shimoda K, Yukitake Y, Kajikawa D, Morio T, Hattori A, Nakagawa M, Ando N, Nishino I, Kato M, Tsunoda T, Saitsu H, Kanemura Y, Yamasaki M, Kosaki K, Matsumoto N, Yoshimori T, Saitoh S. Sci Rep. 2017 Jun 14;7(1):3552. doi: 10.1038/s41598-017-02840-8. PubMed |
| Establishment and long-term culture of human cystic fibrosis endothelial cells. Plebani R, Tripaldi R, Lanuti P, Recchiuti A, Patruno S, Di Silvestre S, Simeone P, Anile M, Venuta F, Prioletta M, Mucilli F, Del Porto P, Marchisio M, Pandolfi A, Romano M. Lab Invest. 2017 Nov;97(11):1375-1384. doi: 10.1038/labinvest.2017.74. Epub 2017 Jul 31. PubMed |
| Palmitoylation-dependent activation of MC1R prevents melanomagenesis. Chen S, Zhu B, Yin C, Liu W, Han C, Chen B, Liu T, Li X, Chen X, Li C, Hu L, Zhou J, Xu ZX, Gao X, Wu X, Goding CR, Cui R. Nature. 2017 Sep 21;549(7672):399-403. doi: 10.1038/nature23887. Epub 2017 Sep 6. PubMed |
| 3-Decylcatechol induces autophagy-mediated cell death through the IRE1alpha/JNK/p62 in hepatocellular carcinoma cells. Go DH, Lee YG, Lee DH, Kim JA, Jo IH, Han YS, Jo YH, Kim KY, Seo YK, Moon JH, Jung CH, Jeon TI. Oncotarget. 2017 May 9;8(35):58790-58800. doi: 10.18632/oncotarget.17732. eCollection 2017 Aug 29. PubMed |
| Merkel cell polyomavirus recruits MYCL to the EP400 complex to promote oncogenesis. Cheng J, Park DE, Berrios C, White EA, Arora R, Yoon R, Branigan T, Xiao T, Westerling T, Federation A, Zeid R, Strober B, Swanson SK, Florens L, Bradner JE, Brown M, Howley PM, Padi M, Washburn MP, DeCaprio JA. PLoS Pathog. 2017 Oct 13;13(10):e1006668. doi: 10.1371/journal.ppat.1006668. eCollection 2017 Oct. PubMed |
| Evolution and clinical impact of co-occurring genetic alterations in advanced-stage EGFR-mutant lung cancers. Blakely CM, Watkins TBK, Wu W, Gini B, Chabon JJ, McCoach CE, McGranahan N, Wilson GA, Birkbak NJ, Olivas VR, Rotow J, Maynard A, Wang V, Gubens MA, Banks KC, Lanman RB, Caulin AF, St John J, Cordero AR, Giannikopoulos P, Simmons AD, Mack PC, Gandara DR, Husain H, Doebele RC, Riess JW, Diehn M, Swanton C, Bivona TG. Nat Genet. 2017 Dec;49(12):1693-1704. doi: 10.1038/ng.3990. Epub 2017 Nov 6. PubMed |
| The protective role of DOT1L in UV-induced melanomagenesis. Zhu B, Chen S, Wang H, Yin C, Han C, Peng C, Liu Z, Wan L, Zhang X, Zhang J, Lian CG, Ma P, Xu ZX, Prince S, Wang T, Gao X, Shi Y, Liu D, Liu M, Wei W, Wei Z, Pan J, Wang Y, Xuan Z, Hess J, Hayward NK, Goding CR, Chen X, Zhou J, Cui R. Nat Commun. 2018 Jan 17;9(1):259. doi: 10.1038/s41467-017-02687-7. PubMed |
| Rapid immunopurification of mitochondria for metabolite profiling and absolute quantification of matrix metabolites. Chen WW, Freinkman E, Sabatini DM. Nat Protoc. 2017 Oct;12(10):2215-2231. doi: 10.1038/nprot.2017.104. Epub 2017 Sep 29. PubMed |
| Amenable epigenetic traits of dental pulp stem cells underlie high capability of xeno-free episomal reprogramming. Thekkeparambil Chandrabose S, Sriram S, Subramanian S, Cheng S, Ong WK, Rozen S, Kasim NHA, Sugii S. Stem Cell Res Ther. 2018 Mar 20;9(1):68. doi: 10.1186/s13287-018-0796-2. PubMed |
| Hsa-miR-155-5p drives aneuploidy at early stages of cellular transformation. Pagotto S, Veronese A, Soranno A, Lanuti P, Di Marco M, Russo MV, Ramassone A, Marchisio M, Simeone P, Guanciali-Franchi PE, Palka G, Costantini RM, Croce CM, Visone R. Oncotarget. 2018 Feb 7;9(16):13036-13047. doi: 10.18632/oncotarget.24437. eCollection 2018 Feb 27. PubMed |
| Production of High-Titer Retrovirus and Lentivirus Vectors. Sena-Esteves M, Gao G. Cold Spring Harb Protoc. 2018 Apr 2;2018(4):pdb.prot095687. doi: 10.1101/pdb.prot095687. PubMed |
| Targeting the upstream transcriptional activator of PD-L1 as an alternative strategy in melanoma therapy. Zhu B, Tang L, Chen S, Yin C, Peng S, Li X, Liu T, Liu W, Han C, Stawski L, Xu ZX, Zhou G, Chen X, Gao X, Goding CR, Xu N, Cui R, Cao P. Oncogene. 2018 Sep;37(36):4941-4954. doi: 10.1038/s41388-018-0314-0. Epub 2018 May 22. PubMed |
| SHLD2/FAM35A co-operates with REV7 to coordinate DNA double-strand break repair pathway choice. Findlay S, Heath J, Luo VM, Malina A, Morin T, Coulombe Y, Djerir B, Li Z, Samiei A, Simo-Cheyou E, Karam M, Bagci H, Rahat D, Grapton D, Lavoie EG, Dove C, Khaled H, Kuasne H, Mann KK, Klein KO, Greenwood CM, Tabach Y, Park M, Cote JF, Masson JY, Marechal A, Orthwein A. EMBO J. 2018 Sep 14;37(18). pii: embj.2018100158. doi: 10.15252/embj.2018100158. Epub 2018 Aug 28. PubMed |
| Tbx1 represses Mef2c gene expression and is correlated with histone 3 deacetylation of the anterior heart field enhancer. Pane LS, Fulcoli FG, Cirino A, Altomonte A, Ferrentino R, Bilio M, Baldini A. Dis Model Mech. 2018 Aug 30;11(9). pii: 11/9/dmm029967. doi: 10.1242/dmm.029967. PubMed |
| SOX2 as a novel contributor of oxidative metabolism in melanoma cells. Andreucci E, Pietrobono S, Peppicelli S, Ruzzolini J, Bianchini F, Biagioni A, Stecca B, Calorini L. Cell Commun Signal. 2018 Nov 22;16(1):87. doi: 10.1186/s12964-018-0297-z. PubMed |
| Pharmacological Targeting of STK19 Inhibits Oncogenic NRAS-Driven Melanomagenesis. Yin C, Zhu B, Zhang T, Liu T, Chen S, Liu Y, Li X, Miao X, Li S, Mi X, Zhang J, Li L, Wei G, Xu ZX, Gao X, Huang C, Wei Z, Goding CR, Wang P, Deng X, Cui R. Cell. 2019 Feb 21;176(5):1113-1127.e16. doi: 10.1016/j.cell.2019.01.002. Epub 2019 Jan 31. PubMed |
| MST1 Suppresses Pancreatic Cancer Progression via ROS-Induced Pyroptosis. Cui J, Zhou Z, Yang H, Jiao F, Li N, Gao Y, Wang L, Chen J, Quan M. Mol Cancer Res. 2019 Jun;17(6):1316-1325. doi: 10.1158/1541-7786.MCR-18-0910. Epub 2019 Feb 22. PubMed |
| Oleic acid-induced defective autolysosome shows impaired lipid degradation. Lee DH, Ahn J, Jang YJ, Ha TY, Jung CH. Biochem Biophys Res Commun. 2019 Jun 4;513(3):553-559. doi: 10.1016/j.bbrc.2019.04.040. Epub 2019 Apr 10. PubMed |
| A Sensitive and Quantitative mKeima Assay for Mitophagy via FACS. Wang C. Curr Protoc Cell Biol. 2020 Mar;86(1):e99. doi: 10.1002/cpcb.99. PubMed |
| c-Src Phosphorylates and Inhibits the Function of the CIC Tumor Suppressor Protein. Bunda S, Heir P, Li ASC, Mamatjan Y, Zadeh G, Aldape K. Mol Cancer Res. 2020 May;18(5):774-786. doi: 10.1158/1541-7786.MCR-18-1370. Epub 2020 Feb 6. PubMed |
| Iridoids of Valeriana fauriei contribute to alleviating hepatic steatosis in obese mice by lipophagy. Lee DH, Park SH, Huh YH, Jung Kim M, Seo HD, Ha TY, Ahn J, Jang YJ, Jung CH. Biomed Pharmacother. 2020 May;125:109950. doi: 10.1016/j.biopha.2020.109950. Epub 2020 Feb 10. PubMed |
| Induction of Cross-Reactive and Protective Antibody Responses After DNA Vaccination With MHCII-Targeted Stem Domain From Influenza Hemagglutinin. Grodeland G, Baranowska-Hustad M, Abadejos J, Blane TR, Teijaro J, Nemazee D, Bogen B. Front Immunol. 2020 Mar 25;11:431. doi: 10.3389/fimmu.2020.00431. eCollection 2020. PubMed |
| HIGD2A is Required for Assembly of the COX3 Module of Human Mitochondrial Complex IV. Hock DH, Reljic B, Ang CS, Muellner-Wong L, Mountford HS, Compton AG, Ryan MT, Thorburn DR, Stroud DA. Mol Cell Proteomics. 2020 Jul;19(7):1145-1160. doi: 10.1074/mcp.RA120.002076. Epub 2020 Apr 21. PubMed |
| Generation of a human iPSC line (MPIi006-A) from a patient with Pelizaeus-Merzbacher disease. Kim KP, Yoon J, Shin B, Ropke A, Han DW, Scholer HR. Stem Cell Res. 2020 Jul;46:101839. doi: 10.1016/j.scr.2020.101839. Epub 2020 May 7. PubMed |
| Generation of two iPS cell lines (HIHDNDi001-A and HIHDNDi001-B) from a Parkinson's disease patient carrying the heterozygous p.A30P mutation in SNCA. Barbuti PA, Santos BFR, Dording CM, Cruciani G, Massart F, Hummel A, Kruger R. Stem Cell Res. 2020 Oct;48:101951. doi: 10.1016/j.scr.2020.101951. Epub 2020 Aug 8. PubMed |
| An Excitable Ras/PI3K/ERK Signaling Network Controls Migration and Oncogenic Transformation in Epithelial Cells. Zhan H, Bhattacharya S, Cai H, Iglesias PA, Huang CH, Devreotes PN. Dev Cell. 2020 Sep 14;54(5):608-623.e5. doi: 10.1016/j.devcel.2020.08.001. Epub 2020 Sep 1. PubMed |
| Decoding myofibroblast origins in human kidney fibrosis. Kuppe C, Ibrahim MM, Kranz J, Zhang X, Ziegler S, Perales-Paton J, Jansen J, Reimer KC, Smith JR, Dobie R, Wilson-Kanamori JR, Halder M, Xu Y, Kabgani N, Kaesler N, Klaus M, Gernhold L, Puelles VG, Huber TB, Boor P, Menzel S, Hoogenboezem RM, Bindels EMJ, Steffens J, Floege J, Schneider RK, Saez-Rodriguez J, Henderson NC, Kramann R. Nature. 2021 Jan;589(7841):281-286. doi: 10.1038/s41586-020-2941-1. Epub 2020 Nov 11. PubMed |
| Human mesenchymal stromal cells do not express ACE2 and TMPRSS2 and are not permissive to SARS-CoV-2 infection. Avanzini MA, Mura M, Percivalle E, Bastaroli F, Croce S, Valsecchi C, Lenta E, Nykjaer G, Cassaniti I, Bagnarino J, Baldanti F, Zecca M, Comoli P, Gnecchi M. Stem Cells Transl Med. 2021 Apr;10(4):636-642. doi: 10.1002/sctm.20-0385. Epub 2021 Jan 26. PubMed |
| Genome-wide Screens Identify Lineage- and Tumor-Specific Genes Modulating MHC-I- and MHC-II-Restricted Immunosurveillance of Human Lymphomas. Dersh D, Phelan JD, Gumina ME, Wang B, Arbuckle JH, Holly J, Kishton RJ, Markowitz TE, Seedhom MO, Fridlyand N, Wright GW, Huang DW, Ceribelli M, Thomas CJ, Lack JB, Restifo NP, Kristie TM, Staudt LM, Yewdell JW. Immunity. 2021 Jan 12;54(1):116-131.e10. doi: 10.1016/j.immuni.2020.11.002. Epub 2020 Dec 2. PubMed |
| Activation of Wnt/beta-catenin signalling and HIF1alpha stabilisation alters pluripotency and differentiation/proliferation properties of human-induced pluripotent stem cells. Wei H, Beeson GC, Ye Z, Zhang J, Yao H, Damon B, Morad M. Biol Cell. 2021 Mar;113(3):133-145. doi: 10.1111/boc.202000055. Epub 2020 Dec 16. PubMed |
| Sorting nexin 5 mediates virus-induced autophagy and immunity. Dong X, Yang Y, Zou Z, Zhao Y, Ci B, Zhong L, Bhave M, Wang L, Kuo YC, Zang X, Zhong R, Aguilera ER, Richardson RB, Simonetti B, Schoggins JW, Pfeiffer JK, Yu L, Zhang X, Xie Y, Schmid SL, Xiao G, Gleeson PA, Ktistakis NT, Cullen PJ, Xavier RJ, Levine B. Nature. 2021 Jan;589(7842):456-461. doi: 10.1038/s41586-020-03056-z. Epub 2020 Dec 16. PubMed |
| Adult-born granule cell mossy fibers preferentially target parvalbumin-positive interneurons surrounded by perineuronal nets. Briones BA, Pisano TJ, Pitcher MN, Haye AE, Diethorn EJ, Engel EA, Cameron HA, Gould E. Hippocampus. 2021 Apr;31(4):375-388. doi: 10.1002/hipo.23296. Epub 2021 Jan 12. PubMed |
| Laser Micro-Irradiation to Study DNA Recruitment During S Phase. Miwatani-Minter B, Rona G. J Vis Exp. 2021 Apr 16;(170). doi: 10.3791/62466. PubMed |
| The biochemical basis of mitochondrial dysfunction in Zellweger Spectrum Disorder. Nuebel E, Morgan JT, Fogarty S, Winter JM, Lettlova S, Berg JA, Chen YC, Kidwell CU, Maschek JA, Clowers KJ, Argyriou C, Chen L, Wittig I, Cox JE, Roh-Johnson M, Braverman N, Bonkowsky J, Gygi SP, Rutter J. EMBO Rep. 2021 Oct 5;22(10):e51991. doi: 10.15252/embr.202051991. Epub 2021 Aug 5. PubMed |
| ZFP423 controls EBF2 coactivator recruitment and PPARgamma occupancy to determine the thermogenic plasticity of adipocytes. Shao M, Zhang Q, Truong A, Shan B, Vishvanath L, Li L, Seale P, Gupta RK. Genes Dev. 2021 Nov 1;35(21-22):1461-1474. doi: 10.1101/gad.348780.121. Epub 2021 Oct 7. PubMed |
| Irisin Stimulates the Release of CXCL1 From Differentiating Human Subcutaneous and Deep-Neck Derived Adipocytes via Upregulation of NFkappaB Pathway. Shaw A, Toth BB, Kiraly R, Arianti R, Csomos I, Poliska S, Vamos A, Korponay-Szabo IR, Bacso Z, Gyory F, Fesus L, Kristof E. Front Cell Dev Biol. 2021 Oct 11;9:737872. doi: 10.3389/fcell.2021.737872. eCollection 2021. PubMed |
| Chromatin-accessibility estimation from single-cell ATAC-seq data with scOpen. Li Z, Kuppe C, Ziegler S, Cheng M, Kabgani N, Menzel S, Zenke M, Kramann R, Costa IG. Nat Commun. 2021 Nov 4;12(1):6386. doi: 10.1038/s41467-021-26530-2. PubMed |
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