pLV-U6-gRNA-UbC-eGFP-P2A-Bsr Citations (8)
Originally described in: CRISPR-Cas9 epigenome editing enables high-throughput screening for functional regulatory elements in the human genome.Klann TS, Black JB, Chellappan M, Safi A, Song L, Hilton IB, Crawford GE, Reddy TE, Gersbach CA Nat Biotechnol. 2017 Apr 3. doi: 10.1038/nbt.3853. PubMed Journal
Articles Citing pLV-U6-gRNA-UbC-eGFP-P2A-Bsr
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| Screening Regulatory Element Function with CRISPR/Cas9-based Epigenome Editing. Klann TS, Crawford GE, Reddy TE, Gersbach CA. Methods Mol Biol. 2018;1767:447-480. doi: 10.1007/978-1-4939-7774-1_25. PubMed |
| Master Regulators and Cofactors of Human Neuronal Cell Fate Specification Identified by CRISPR Gene Activation Screens. Black JB, McCutcheon SR, Dube S, Barrera A, Klann TS, Rice GA, Adkar SS, Soderling SH, Reddy TE, Gersbach CA. Cell Rep. 2020 Dec 1;33(9):108460. doi: 10.1016/j.celrep.2020.108460. PubMed |
| Epigenome editing of the CFTR-locus for treatment of cystic fibrosis. Kabadi AM, Machlin L, Dalal N, Lee RE, McDowell I, Shah NN, Drowley L, Randell SH, Reddy TE. J Cyst Fibros. 2021 May 25. pii: S1569-1993(21)00118-1. doi: 10.1016/j.jcf.2021.04.008. PubMed |
| Chromatin Remodeling of Colorectal Cancer Liver Metastasis is Mediated by an HGF-PU.1-DPP4 Axis. Wang L, Wang E, Prado Balcazar J, Wu Z, Xiang K, Wang Y, Huang Q, Negrete M, Chen KY, Li W, Fu Y, Dohlman A, Mines R, Zhang L, Kobayashi Y, Chen T, Shi G, Shen JP, Kopetz S, Tata PR, Moreno V, Gersbach C, Crawford G, Hsu D, Huang E, Bu P, Shen X. Adv Sci (Weinh). 2021 Oct;8(19):e2004673. doi: 10.1002/advs.202004673. Epub 2021 Aug 10. PubMed |
| Antispacer peptide nucleic acids for sequence-specific CRISPR-Cas9 modulation. Economos NG, Quijano E, Carufe KEW, Perera JDR, Glazer PM. Nucleic Acids Res. 2022 Jun 10;50(10):e59. doi: 10.1093/nar/gkac095. PubMed |
| Activation of the imprinted Prader-Willi Syndrome locus by CRISPR-based epigenome editing. Rohm D, Black JB, McCutcheon SR, Barrera A, Morone DJ, Nuttle X, de Esch CE, Tai DJC, Talkowski ME, Iglesias N, Gersbach CA. bioRxiv [Preprint]. 2024 Mar 4:2024.03.03.583177. doi: 10.1101/2024.03.03.583177. PubMed |
| Enhancer-targeted CRISPR-Activation Rescues Haploinsufficient Autism Susceptibility Genes. Chen GT, Nair G, Osorio AJ, Holley SM, Ghassemzadeh K, Gonzalez J, Lu C, Sanjana NE, Cepeda C, Geschwind DH. bioRxiv [Preprint]. 2024 Mar 14:2024.03.13.584921. doi: 10.1101/2024.03.13.584921. PubMed |
| Integrated enhancer regulatory network by enhancer-promoter looping in gastric cancer. Zhu T, Okabe A, Usui G, Fujiki R, Komiyama D, Huang KK, Seki M, Fukuyo M, Abe H, Ning M, Okada T, Minami M, Matsumoto M, Fan Q, Rahmutulla B, Hoshii T, Tan P, Morikawa T, Ushiku T, Kaneda A. NAR Cancer. 2024 May 8;6(2):zcae020. doi: 10.1093/narcan/zcae020. eCollection 2024 Jun. PubMed |
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